American Journal of Public Health, 104(9), 1783-1787
Increasing 25-hydroxyvitamin D serum levels can prevent a wide range of diseases. There is a concern about increasing kidney stone risk with vitamin D supplementation. We used GrassrootsHealth data to examine the relationship between vitamin D status and kidney stone incidence.
The study included 2012 participants followed prospectively for a median of 19 months. Thirteen individuals self-reported kidney stones during the study period. Multivariate logistic regression was applied to assess the association between vitamin D status and kidney stones.
We found no statistically significant association between serum 25-hydroxyvitamin D and kidney stones (P = .42). Body mass index was significantly associated with kidney stone risk (odds ratio = 3.5; 95% confidence interval = 1.1, 11.3).
We concluded that a serum 25-hydroxyvitamin D level of 20 to 100 nanograms per milliliter has no significant association with kidney stone incidence.
Nguyen, S., Baggerly, L., French, C., Heaney, R. P., Gorham, E. D., & Garland, C. F. (2014). 25-Hydroxyvitamin D in the range of 20 to 100 ng/mL and incidence of kidney stones. *American journal of public health*, *104*(9), 1783-1787. https://doi.org/10.2105/AJPH.2013.301368
Nguyen S, Baggerly L, French C, Heaney RP, Gorham ED, Garland CF. 25-Hydroxyvitamin D in the range of 20 to 100 ng/mL and incidence of kidney stones. Am J Public Health. 2014;104(9):1783-1787. doi:10.2105/AJPH.2013.301368
Nguyen, S., et al. "25-Hydroxyvitamin D in the range of 20 to 100 ng/mL and incidence of kidney stones." *American journal of public health*, vol. 104, no. 9, 2014, pp. 1783-1787.
Adult, Age Factors, Body Mass Index, Dietary Supplements, Female, Humans, Incidence, Kidney Calculi/blood/epidemiology, Male, Middle Aged, Risk Factors, Sex Factors, Vitamin D/analogs & Derivatives/blood, Vitamin D, 25-hydroxyvitamin D