American Journal of Obstetrics and Gynecology, 156(2), 449-454
C-reactive protein has been used to identify patients at high risk for infectious morbidity with preterm labor or preterm rupture of membranes. In this article we report on 104 patients with preterm labor symptoms (n = 45) or preterm rupture of the membranes (n = 59) and serial evaluations of C-reactive protein measured by latex agglutination and laser nephelometry. The simple, inexpensive latex method appears comparable to the laser method in predicting infectious morbidity and can be used clinically. Elevated C-reactive protein values before delivery predict infectious morbidity in only 8% to 29% of patients, and up to 18% of patients with serious infections may be misdiagnosed as having normal C-reactive protein values before delivery.
Ernest, J. M., Swain, M., Block, S. M., Nelson, L. H., Hatjis, C. G., & Meis, P. J. (1987). C-reactive protein: a limited test for managing patients with preterm labor or preterm rupture of membranes?. *American journal of obstetrics and gynecology*, *156*(2), 449-454. https://doi.org/10.1016/0002-9378(87)90306-1
Ernest JM, Swain M, Block SM, Nelson LH, Hatjis CG, Meis PJ. C-reactive protein: a limited test for managing patients with preterm labor or preterm rupture of membranes?. Am J Obstet Gynecol. 1987;156(2):449-454. doi:10.1016/0002-9378(87)90306-1
Ernest, J. M., et al. "C-reactive protein: a limited test for managing patients with preterm labor or preterm rupture of membranes?." *American journal of obstetrics and gynecology*, vol. 156, no. 2, 1987, pp. 449-454.
C-Reactive Protein/analysis, Chorioamnionitis/diagnosis, Female, Fetal Diseases/diagnosis, Fetal Membranes, Premature Rupture/therapy, Humans, Infections/diagnosis, Obstetric Labor, Premature/therapy, Pregnancy, C-Reactive Protein