Changes in circulating hormone levels after ovarian wedge resection in patients with polycystic ovary syndrome

Archives of Gynecology and Obstetrics, 248(1), 31-35

DOI 10.1007/BF02389587 PMID 2124095

Abstract

Serum gonadotropin, prolactin, estradiol, sex hormone binding globulin (SHBG) and androgen levels were measured before, 5 days and 6 weeks following ovarian wedge resection in 9 patients with polycystic ovary syndrome. Elevated levels of LH, androstenedione, testosterone and dehydroepiandrosterone-sulphate (DHEA-S) were found before surgery. There was a marked decrease in androstenedione and DHEA-S levels 5 days following wedge resection, but a rebound effect could be observed 6 weeks later. Serum gonadotropin, prolactin, testosterone and SHBG concentrations were practically unaffected by surgery. At 6-12 months follow up patients showed regular, mainly ovulatory cycles, but pregnancy occurred only in two cases.

Topics

ovarian wedge resection polycystic ovary syndrome hormonal changes, PCOS wedge resection androgen levels gonadotropins, surgical treatment polycystic ovary syndrome ovulation restoration, ovarian wedge resection androstenedione DHEA-S decrease, PCOS wedge resection ovulatory cycles pregnancy outcomes, Szilágyi PCOS ovarian wedge resection hormones, polycystic ovary surgery rebound androgen effect, SHBG testosterone LH after ovarian wedge resection, PCOS surgical treatment hormonal follow-up, bilateral ovarian wedge resection fertility outcomes
PMID 2124095 2124095 DOI 10.1007/BF02389587 10.1007/BF02389587

Cite this article

Szilágyi, A., Rossmanith, W., Csermely, T., & Csaba, I. (1990). Changes in circulating hormone levels after ovarian wedge resection in patients with polycystic ovary syndrome. *Archives of gynecology and obstetrics*, *248*(1), 31-35. https://doi.org/10.1007/BF02389587

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