Fertility and Sterility, 42(4), 548-553
Twenty-five infertile women conceived while taking tamoxifen (TMX). Daily serum profiles of 5 of the 25 TMX-induced conception cycles were elucidated and compared with those found in 5 normal cycles. In spite of lower levels of follicle-stimulating hormone and luteinizing hormone during the follicular phases, estradiol concentrations were higher in the TMX-induced conception cycles. It is suggested that this may be due to a direct ovarian effect of TMX as one of its major mechanisms in the course of folliculogenesis. On the other hand, progesterone concentrations on days 6 and 7 during the luteal phases were also higher in the TMX-induced conception cycles. It is suggested that this may be due to a luteotropic influence at the blastocyst stage.
Tajima, C. (1984). Endocrine profiles in tamoxifen-induced conception cycles. *Fertility and sterility*, *42*(4), 548-553. https://doi.org/10.1016/s0015-0282(16)48137-9
Tajima C. Endocrine profiles in tamoxifen-induced conception cycles. Fertil Steril. 1984;42(4):548-553. doi:10.1016/s0015-0282(16)48137-9
Tajima, C. "Endocrine profiles in tamoxifen-induced conception cycles." *Fertility and sterility*, vol. 42, no. 4, 1984, pp. 548-553.
Adult, Estradiol/blood, Female, Follicle Stimulating Hormone/blood, Humans, Infertility, Female/blood/drug Therapy, Luteinizing Hormone/blood, Progesterone/blood, Tamoxifen/therapeutic Use, Tamoxifen, Progesterone, Estradiol, Luteinizing Hormone, Follicle Stimulating Hormone,