Hormone-related risk factors for breast cancer in women under age 50 years by estrogen and progesterone receptor status: results from a case-control and a case-case comparison

Breast Cancer Research : BCR, 8(4), R39

DOI 10.1186/bcr1514 PMID 16846528

Abstract

Introduction

It has been suggested that hormonal risk factors act predominantly on estrogen receptor and progesterone receptor (ER/PR)-positive breast cancers. However, the data have been inconsistent, especially in younger women.

Methods

We evaluated the impact of age at menarche, pregnancy history, duration of breastfeeding, body mass index, combined oral contraceptive use, and alcohol consumption on breast cancer risk by ER/PR status in 1,725 population-based case patients and 440 control subjects aged 20 to 49 years identified within neighborhoods of case patients. We used multivariable unconditional logistic regression methods to conduct case-control comparisons overall as well as by

Topics

breast cancer hormone-related risk, ER PR receptor status cancer, oral contraceptive breast cancer young women, reproductive factors cancer subtype, age at menarche breast cancer, breastfeeding cancer protection, BMI breast cancer risk, population-based case-control cancer, estrogen receptor-positive cancer, progesterone receptor breast cancer
PMID 16846528 16846528 DOI 10.1186/bcr1514 10.1186/bcr1514

Cite this article

Ma, H., Bernstein, L., Ross, R. K., & Ursin, G. (2006). Hormone-related risk factors for breast cancer in women under age 50 years by estrogen and progesterone receptor status: results from a case-control and a case-case comparison. *Breast cancer research : BCR*, *8*(4), R39. https://doi.org/10.1186/bcr1514

Related articles