Fertility and Sterility, 62(4), 708-710
To investigate the efficacy of hCG in the management of recurrent early pregnancy loss.
A prospective, randomized, controlled trial.
Miscarriage Clinic, Women's Hospital, Liverpool, United Kingdom.
Eighty-one women attending the miscarriage clinic with idiopathic recurrent pregnancy loss were randomized to receive hCG supplementation or placebo in early pregnancy.
The success rate or live birth rate.
In women with regular menstrual cycles it was found that hCG had no beneficial effect, the pregnancy success rate being 86% in both groups. However, women with oligomenorrhea had a pregnancy success rate of 40% in the placebo group but a statistically significant improvement to 86% if hCG was given.
Human chorionic gonadotropin can be recommended for idiopathic recurrent pregnancy loss in women with oligomenorrhea.
Quenby, S., & Farquharson, R. G. (1994). Human chorionic gonadotropin supplementation in recurring pregnancy loss: a controlled trial. *Fertility and sterility*, *62*(4), 708-710. https://doi.org/10.1016/s0015-0282(16)56992-1
Quenby S, Farquharson RG. Human chorionic gonadotropin supplementation in recurring pregnancy loss: a controlled trial. Fertil Steril. 1994;62(4):708-710. doi:10.1016/s0015-0282(16)56992-1
Quenby, S., and R. G. Farquharson. "Human chorionic gonadotropin supplementation in recurring pregnancy loss: a controlled trial." *Fertility and sterility*, vol. 62, no. 4, 1994, pp. 708-710.
Abortion, Habitual/complications/drug Therapy, Adult, Chorionic Gonadotropin/therapeutic Use, Female, Humans, Menstrual Cycle, Oligomenorrhea/complications, Pregnancy, Pregnancy Outcome, Prospective Studies, Reference Values, Chorionic Gonadotropin,