Indispensability of the human corpus luteum in the maintenance of early pregnancy. Luteectomy evidence

Obstetrical & Gynecological Survey, 33(2), 69-81

DOI 10.1097/00006254-197802000-00001 PMID 341008

Abstract

Following Fraenkel's discovery, demonstrating that the rabbit corpora lutea are indispensable in pregnancy maintenance, Corner and Allen showed (1) in a series of now classic studies that luteectomy predictably terminates pregnancy, except when progesterone is provided as substitution therapy. Despite the clarity of these demonstrations and the accumulation of complementary data over 40 years (2, 3, 4), many investigators held the view that the studies in the rabbit model failed to establish a basic biological law of broad …

Topics

corpus luteum indispensable early pregnancy maintenance, luteectomy early pregnancy progesterone substitution therapy, Csapo Pulkkinen corpus luteum pregnancy maintenance, corpus luteum removal pregnancy termination evidence, progesterone support early pregnancy corpus luteum function, luteal phase progesterone essential pregnancy maintenance human, Fraenkel Corner Allen corpus luteum pregnancy classic studies, luteectomy evidence human pregnancy corpus luteum requirement, early pregnancy luteal progesterone dependence, corpus luteum progesterone pregnancy biological law
PMID 341008 341008 DOI 10.1097/00006254-197802000-00001 10.1097/00006254-197802000-00001

Cite this article

Csapo, A. I., & Pulkkinen, M. (1978). Indispensability of the human corpus luteum in the maintenance of early pregnancy. Luteectomy evidence. *Obstetrical & gynecological survey*, *33*(2), 69-81. https://doi.org/10.1097/00006254-197802000-00001

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