We studied endometrial luteal phase in specimens from 660 biopsies done in 300 patients from our infertility clinic. A minimum of two (240 women) or three (60 women) endometrial biopsy specimens from separate cycles were taken regardless of the previous histologic findings in all patients. Statistical analysis of results by the McNemar and the Cochran Q tests for the significance of changes leads us to conclude that a minimum of two, and even three, endometrial biopsy specimens are needed for diagnosis of luteal phase deficiency.
Balasch, J. C., Vanrell, J. A., Creus, M., Márquez, M., & González-Merlo, J. (1985). The endometrial biopsy for diagnosis of luteal phase deficiency. *Fertility and sterility*, *44*(5), 699-701. https://doi.org/10.1016/s0015-0282(16)48990-9
Balasch JC, Vanrell JA, Creus M, Márquez M, González-Merlo J. The endometrial biopsy for diagnosis of luteal phase deficiency. Fertil Steril. 1985;44(5):699-701. doi:10.1016/s0015-0282(16)48990-9
Balasch, Joan Carles, et al. "The endometrial biopsy for diagnosis of luteal phase deficiency." *Fertility and sterility*, vol. 44, no. 5, 1985, pp. 699-701.
Sixty-three endometrial biopsies were dated histologically by using the standard criteria on two separate occasions by the same observer. Overall, it was found that exact agreement occurred in 15 (24%...
Introduction: Luteal phase deficiency (LPD), while commonly observed and managed in stimulated in-vitro fertilisation cycles, is a more contentious phenomenon in natural cycles. The challenge arises i...
OBJECTIVE: To assess the sensitivity and specificity of common clinical tests used for the diagnosis of luteal phase defect (LPD).
DESIGN: The sensitivity and specificity of these tests for predicti...