Buskmiller, C. (2018). The Ethics of Interstitial and Cesarean Scar Ectopic Pregnancies: Four Case Studies and a Review of the Literature. The Linacre Quarterly, 85(3), 252-269. https://doi.org/10.1177/0024363918788858
Buskmiller C. The Ethics of Interstitial and Cesarean Scar Ectopic Pregnancies: Four Case Studies and a Review of the Literature. Linacre Q. 2018;85(3):252-269. doi:10.1177/0024363918788858
Buskmiller, Cara. "The Ethics of Interstitial and Cesarean Scar Ectopic Pregnancies: Four Case Studies and a Review of the Literature." The Linacre Quarterly, vol. 85, no. 3, 2018, pp. 252-269.
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Department of Obstetrics, Gynecology, and Women’s Health, St. Louis University, St. Louis, MO, USA01p7jjy08
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RRM Academy Synopsis
Catholic review rates two ectopic surgeries morally acceptable
A Catholic ethics review rates cornual wedge resection and scar excision as morally acceptable for two rare ectopic pregnancies. The author studied published care and four cases from one Catholic hospital. Methotrexate was less clear. Potassium chloride was ruled out.
Study at a glance, ethics review of four cases: A Catholic ethics review rates two ectopic surgeries acceptable. Source: Buskmiller C, 2018, PMID 30275610.
Key Findings
The author rated cornual wedge resection, vasopressin use and scar excision morally acceptable. Less clearly licit were aspiration of gestational sac contents, cornuostomy, gestational excision for cesarean scar pregnancies and methotrexate.
The author called techniques that lead to direct abortion certainly illicit. The examples were D&Cs on live embryos or fetuses, potassium chloride and the double-balloon catheter.
Ectopic pregnancies outside the extrauterine fallopian tube make up 7–10 percent of the total. Interstitial pregnancies are 2.5 percent of ectopic pregnancies, and cesarean scar pregnancies are 4.2 percent.
For cesarean scar pregnancy, one review found systemic methotrexate successful in 8.7 percent of cases, with a 13 percent complication rate. Surgical resection by any approach succeeded in 92 percent of cases.
Two cases ended in hysterectomy: a ruptured interstitial pregnancy at seventeen weeks (seven liters blood loss), and a salvaged scar pregnancy delivered live at thirty weeks and six days (sixteen liters).
Interpretation
This review uses Catholic moral theology, mainly the rule of double effect, to rate each approach to these ectopic pregnancies. The ratings reflect the author's own reading of published case reports and hospital records. The author notes that no study yet compares the more than thirty proposed approaches to cesarean scar pregnancy. The findings support larger studies of these surgical approaches.
RRM Context
Restorative reproductive medicine values a woman's future fertility and treating the root cause. This review says doctors should generally avoid hysterectomy to protect fertility. For a repeat interstitial pregnancy, it calls surgery the best way to treat the likely cause in the mother.
Our editorial summary of this paper, not the article's abstract.
Abstract
Catholic bioethicists have extensively addressed extrauterine tubal pregnancies, which represent the great majority of ectopic pregnancies. However, additional management options have been developed for the other 7-10 percent of ectopic pregnancies. Using two cases of interstitial pregnancy and two cases of cesarean scar pregnancy (CSP) seen at a Catholic tertiary care center, this article discusses options including expectant management, systemic methotrexate, intragestational methotrexate, intragestational potassium chloride, uterine artery embolization, dilation and curettage (D&C), vasopressin use, cornuostomy, cornual wedge resection, CSP evacuation, CSP scar excision, CSP salvage, and hysterectomy. Cornual wedge resection, vasopressin use, and CSP scar excision are morally acceptable; less clearly licit are aspiration of gestational sac contents, cornuostomy, gestational excision for CSPs, and methotrexate. Certainly illicit are any techniques leading to direct abortion such as D&Cs on live embryos or fetuses, double-balloon catheter placement, and use of potassium chloride.
Summary
An ectopic pregnancy is any pregnancy outside the uterus. These are dangerous because the pregnancy can burst out of its abnormal location and cause life-threatening internal bleeding. Most are in the part of the fallopian tube outside the uterus, but there are other types, including interstitial pregnancies (located in the part of the tube tunneling through the uterine wall) and cesarean scar pregnancies (buried in the uterine scar where the cut for a C-section was made). This article lists the ways that physicians prevent women from dying from interstitial and cesarean scar pregnancies and proposes which treatments are morally acceptable.
A uterine isthmocele is a pouch-like defect at the cesarean scar that causes postmenstrual spotting, pelvic pain, and secondary infertility. Diagnosis, repair options, and the restorative approach.