Measurement of serum LH, FSH, estradiol and progesterone in disorders of the human menstrual cycle: the inadequate luteal phase

Sherman BM, Korenman SG

doi:10.1210/jcem-39-1-145

Measurement of serum LH, FSH, estradiol and progesterone in disorders of the human menstrual cycle: the inadequate luteal phase

Sherman BM et al., 1974

The Journal of Clinical Endocrinology and Metabolism, 39(1), 145-149

DOI 10.1210/jcem-39-1-145

Abstract

The irregular menses experienced by obese and/or hirsute women were studied by daily measurement of serum LH, FSH, estradiol (E2) and progesterone (P). During 8 cycles of 24 to 157 days, each episode of menstrual bleeding was preceded by hormonal evidence of follicular maturation and corpus luteum formation. The premenstrual fluctuations of LH and E2 were not different from those observed in normal cycles. Although the luteal phase was of more than 10 days' duration, progesterone secretion was subnormal during each cycle. Serum FSH was low throughout the time preceding the LH/FSH surge. These data suggest that inadequate corpus luteum progesterone secretion may be characteristic of the menstrual cycles in oligomenorrheic, obese infertile women.

Topics

Reproductive Endocrinology > Luteal Phase > Deficiency Reproductive Endocrinology > Progesterone > Assays Diagnostics > Hormone Assays > Progesterone Infertility > Female Factor > Ovulatory Dysfunction

luteal phase deficiency diagnosis, inadequate luteal phase progesterone, daily hormone monitoring menstrual cycle, progesterone deficiency oligomenorrhea, luteal phase insufficiency obese women, corpus luteum dysfunction, daily lh fsh measurement, progesterone secretion luteal phase, oligomenorrhea infertility hormonal evaluation, inadequate progesterone infertility, luteal phase defect biomarkers, daily estradiol monitoring cycle

Cite this article

Sherman, B. M., & Korenman, S. G. (1974). Measurement of serum LH, FSH, estradiol and progesterone in disorders of the human menstrual cycle: the inadequate luteal phase. *The Journal of clinical endocrinology and metabolism*, *39*(1), 145-149. https://doi.org/10.1210/jcem-39-1-145

Keywords

Adult, Amenorrhea/blood/physiopathology, Corpus Luteum/metabolism/physiopathology, Estradiol/blood, Female, Follicle Stimulating Hormone/blood, Hirsutism/complications, Humans, Luteinizing Hormone/blood, Menstruation, Obesity/complications, Progesterone/blood/metabolism, Time Factors, Progesterone, Estradiol, Luteinizing Hormone, Follicle Stimulating Hormone,

Measurement of serum LH, FSH, estradiol and progesterone in disorders of the human menstrual cycle: the inadequate luteal phase

Abstract

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Cite this article

Keywords

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