Risk factors for anxiety and depression among pregnant women during the COVID-19 pandemic: Results of a web-based multinational cross-sectional study

Kajdy A, Sys D, Pokropek A, Shaw SW, Chang TY, Calda P, Acharya G, Ben-Zion M, Biron-Shental T, Borowski D, Czuba B, Etchegaray A, Feduniw S, Garcia-Mandujano R, Santacruz MG, Gil MM, Hassan S, Kwiatkowski S, Martin-Arias A, Martinez-Portilla RJ, Prefumo F, Rabijewski M, Salomon LJ, Tiller H, Verlohren S, Voon HY, Yanque-Robles OF, Yong SL, Poon LC, Mind-COVID Collaborative Team

Published January 2023 International Journal of Gynaecology and Obstetrics: the Official Organ of the International Federation of Gynaecology and Obstetrics, 160(1), 167-186
DOI 10.1002/ijgo.14388 PMID 35932096 PMC PMC9538861

Abstract

Objective

To assess risk factors for anxiety and depression among pregnant women during the COVID-19 pandemic using Mind-COVID, a prospective cross-sectional study that compares outcomes in middle-income economies and high-income economies.

Methods

A total of 7102 pregnant women from 12 high-income economies and nine middle-income economies were included. The web-based survey used two standardized instruments, General Anxiety Disorder-7 (GAD-7) and Patient Health Questionnaire-9 (PHQ-9).

Result

Pregnant women in high-income economies reported higher PHQ-9 (0.18 standard deviation [SD], P < 0.001) and GAD-7 (0.08 SD, P = 0.005) scores than those living in middle-income economies. Multivariate regression analysis showed that increasing PHQ-9 and GAD-7 scales were associated with mental health problems during pregnancy and the need for psychiatric treatment before pregnancy. PHQ-9 was associated with a feeling of burden related to restrictions in social distancing, and access to leisure activities. GAD-7 scores were associated with a pregnancy-related complication, fear of adverse outcomes in children related to COVID-19, and feeling of burden related to finances.

Conclusions

According to this study, the imposed public health measures and hospital restrictions have left pregnant women more vulnerable during these difficult times. Adequate partner and family support during pregnancy and childbirth can be one of the most important protective factors against anxiety and depression, regardless of national economic status.

By this author

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Anna Kajdy, Dorota Sys, Artur Pokropek, Steven W Shaw, Tung-Yao Chang, Pavel Calda, Ganesh Acharya, Maya Ben-Zion, Tal Biron-Shental, Dariusz Borowski, Bartosz Czuba, Adolfo Etchegaray, Stepan Feduniw, Rosario Garcia-Mandujano, Monica Garcia Santacruz, Maria M Gil, Sonia Hassan, Sebastian Kwiatkowski, Arancha Martin-Arias, Raigam Jafet Martinez-Portilla, Federico Prefumo, Michał Rabijewski, Laurent J Salomon, Heidi Tiller, Stefan Verlohren, Hian Yan Voon, Omar Fernando Yanque-Robles, Soon Leong Yong, Liona C Poon
A Kajdy, D Sys, A Pokropek, Steve Shaw, S Shaw, T Chang, P Calda, G Acharya, M Ben-Zion, T Biron-Shental, D Borowski, B Czuba, A Etchegaray, S Feduniw, R Garcia-Mandujano, M Santacruz, M Gil, S Hassan, S Kwiatkowski, A Martin-Arias, R Martinez-Portilla, F Prefumo, M Rabijewski, L Salomon, H Tiller, S Verlohren, H Voon, O Yanque-Robles, S Yong, L Poon
PMID 35932096 35932096 DOI 10.1002/ijgo.14388 10.1002/ijgo.14388 Kajdy et al. 2023, Kajdy 2023