Neurology, 35(10), 1466-1468
We describe 16 patients with neuropathy associated with pyridoxine abuse. The clinical picture of a pure sensory central-peripheral distal axonopathy was consistent. Pyridoxine dose was 0.2 to 5 g/d, and duration of consumption before symptoms was inversely proportional to the daily intake. In all patients with adequate follow-up, improvement followed discontinuation of pyridoxine. The ready availability of up to 1-gram tablets makes it likely that this neuropathy will continue to be seen.
Parry, G. J., & Bredesen, D. E. (1985). Sensory neuropathy with low-dose pyridoxine. *Neurology*, *35*(10), 1466-1468. https://doi.org/10.1212/wnl.35.10.1466
Parry GJ, Bredesen DE. Sensory neuropathy with low-dose pyridoxine. Neurology. 1985;35(10):1466-1468. doi:10.1212/wnl.35.10.1466
Parry, Gareth J., and Dale E. Bredesen. "Sensory neuropathy with low-dose pyridoxine." *Neurology*, vol. 35, no. 10, 1985, pp. 1466-1468.
Adult, Female, Humans, Male, Middle Aged, Peripheral Nervous System Diseases/chemically Induced, Pyridoxine/adverse Effects, Sensation, Substance-Related Disorders/physiopathology, Pyridoxine,