Obstetrics and Gynecology, 57(5), 661-665
Marked improvement in the severe hypertension (250/150 mmHg) and hirsutism of a patient suffering from polycystic ovary syndrome was quickly achieved by the use of spironolactone 200 mg per day. Substitution of spironolactone with bromocriptine induced further amelioration of these symptoms and renewal of ovulatory cycles. These drugs may afford another mode of therapy in patients with polycystic ovary syndrome.
Blum, I., Kaufman, H., Marilus, R., Rusecki, Y., & Chovers, I. (1981). Successful treatment of polycystic ovary syndrome with spironolactone or bromocriptine. *Obstetrics and gynecology*, *57*(5), 661-665.
Blum I, Kaufman H, Marilus R, Rusecki Y, Chovers I. Successful treatment of polycystic ovary syndrome with spironolactone or bromocriptine. Obstet Gynecol. 1981;57(5):661-665.
Blum, I., et al. "Successful treatment of polycystic ovary syndrome with spironolactone or bromocriptine." *Obstetrics and gynecology*, vol. 57, no. 5, 1981, pp. 661-665.
Adult, Bromocriptine/therapeutic Use, Female, Hirsutism/drug Therapy/etiology, Hormones/analysis, Humans, Hypertension/drug Therapy/etiology, Polycystic Ovary Syndrome/complications/drug Therapy, Spironolactone/therapeutic Use, Hormones, Spironolactone, Bromocriptine