Reports on clinical uses of platelet-rich plasma (PRP) have dramatically increased in the last decade. Indications for PRP therapy range from muscle and skeletal injuries to hair re-growth. More recently evidences have shown its positive effects in promoting endometrial and follicular growth and gestation in assisted reproduction cycles. We discuss the putative role of PRP on endometrial receptivity, with a brief history of its applications in research and clinical therapies. Despite its widespread uses in medicine, the mechanisms through which PRP exerts its regenerative effects are only postulated, not based on scientific data. There is an unmet need for advanced research to corroborate present findings in the clinical scenario.
Bos-Mikich, A., De Oliveira, R., & Frantz, N. (2018). Platelet-rich plasma therapy and reproductive medicine. *Journal of assisted reproduction and genetics*, *35*(5), 753-756. https://doi.org/10.1007/s10815-018-1159-8
Bos-Mikich A, De Oliveira R, Frantz N. Platelet-rich plasma therapy and reproductive medicine. J Assist Reprod Genet. 2018;35(5):753-756. doi:10.1007/s10815-018-1159-8
Bos-Mikich, Adriana, et al. "Platelet-rich plasma therapy and reproductive medicine." *Journal of assisted reproduction and genetics*, vol. 35, no. 5, 2018, pp. 753-756.
Vitagliano A et al., 2022
Open Access
Diagnostics (Basel, Switzerland)
This systematic review and meta-analysis aims to evaluate the impact of chronic endometritis (CE) and its therapy on in vitro fertilization (IVF) outcome. Additionally, we aim to investigate whether v...
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Vitagliano A et al., 2021
Open Access
Diagnostics (Basel, Switzerland)
Background: Chronic endometritis (CE) and endometrial polyps (EPs) are common conditions in reproductive age women. CE is an infectious disorder of the endometrium characterized by signs of chronic in...