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Background: Perand polyfluoroalkyl substances (PFAS) exposure is widespread and has been linked with gynecologic disease. To our knowledge, no study has measured PFAS in endometrial tissue. Methods: ...

# Fertility treatment 2023: trends and figures Preliminary UK statistics for IVF and DI treatment, storage, and donation Published: June 2025 You have chosen not to allow videos from the 3rd party str...

Prenatal exposure to air pollution is an important risk factor for child health outcomes, including asthma. Identification of DNA methylation changes associated with air pollutant exposure can provide...

Importance: Identifying atypical body mass index (BMI) trajectories in children and understanding associated, modifiable early-life factors may help prevent childhood obesity. Objective: To character...

Background: Ovarian hormones affect cardiovascular health yet few sufficient-sized studies with reliable ovulatory documentation have assessed the QTc-hormonal relationship. This study investigated QT...

Breast tenderness and swelling are associated with premenstrual symptoms but are not well described in healthy women. In this 1-year prospective observational study, we examined daily breast tendernes...

Importance: Medical gaslighting, in which a patient's concerns are dismissed without proper evaluation, has been described anecdotally in vulvovaginal patient care, but has not been quantified. Objec...

Objectives: This study aimed to elucidate the effects of messenger RNA (mRNA) and inactivated coronavirus disease 2019 (COVID-19) vaccines on ovarian histology and reserve in rats. Methods: Thirty fe...

STUDY Question: Are dietary patterns associated with age at menarche after accounting for BMI-for-age (BMIz) and height? SUMMARY ANSWER: We observed associations between both the Alternative Healthy ...

Objective: There is considerable individual day-to-day variation within the menstrual cycle and between cycles in women. Average hormone curves inadequately describe the individual hormone patterns ex...

Objectives: The objective of this study is to test the association between preconception polycystic ovary syndrome (PCOS) and gestational diabetes mellitus (GDM) using Utah's Pregnancy Risk Assessment...

Urtica dioica is widely distributed across temperate regions of the world and is highly beneficial and packed with nutritional value including a rich profile of phytochemicals, amino acids, and essent...

STUDY Question: What is the association between endometriosis and the type and age of menopause? SUMMARY ANSWER: Women with endometriosis had a 7-fold increased risk of undergoing surgical menopause ...

There is growing interest in the use of microbial-seeding interventions to mitigate the impacts of prenatal antibiotics, C-section, and lack of breastfeeding on mother-child microbe sharing. However, ...

Restorative reproductive surgery has emerged to become an exciting and promising field of surgery that can transform the way that we treat patients, especially regarding fertility. As a prime example ...

The gut microbiome influences the metabolism and health of several organs beyond the gut and has recently gained considerable attention. The gut plays a central role in food digestion, absorption, nut...

In 1972, a seminal article was published demonstrating that women, adequately trained, could detect the approach of ovulation in the fertile window of their menstrual cycle. It was demonstrated that t...

Background Low-cost sensors (LCS) are widely used for air quality monitoring, but their accuracy depends on proper calibration. This study compares linear regression (LR) and machine learning (ML) tec...

Background: Measuring quantitative menstrual cycle hormones at home may help women better understand their postpartum and perimenopause fertility transitions, but these quantitative fertility monitors...

Ectopic pregnancy occurs when a fertilized egg implants outside the uterine cavity, a condition that affects approximately 1% to 2% of pregnancies in the United States. Ectopic pregnancy is a potentia...

Objective: To investigate the efficacy and safety of open-label placebos (OLP) in premenstrual syndrome (PMS). Design: Randomised controlled trial. Setting: Switzerland, 2018-2020. Participants: 150 ...

Background: Previous research on the role of maternal diet in relation to autism has focused on examining individual nutrient associations. Few studies have examined associations with multiple nutrien...

Introduction: Endometriosis, affecting 11% of reproductive-aged persons, is characterized by ectopic endometrial tissue and chronic inflammation. Prior research suggests those with endometriosis have ...

Background: Individuals with endometriosis, a gynecologic condition affecting approximately 11% of people with a uterus, may have an elevated risk for developing cardiovascular disease (CVD) later in ...

IN BRIEF: Progesterone supplementation reverses 83% of transcript changes in the secretory endometrium induced by postovulatory mifepristone, potentially mitigating its antiprogestogenic effects. ABST...

Self-reported dietary intake varies across menstrual cycle phases, but objective assessments of dietary intake together with appetite and resting metabolic rate (RMR) are limited. This study aimed to ...

Prevalence of autism diagnosis has historically differed by demographic factors. Using data from 8224 participants drawn from the Environmental influences on Child Health Outcomes (ECHO) Program, we e...

Objective: To evaluate the association between contemporary hormonal contraceptive use and the risk of incident ischaemic stroke and myocardial infarction. Design: Real-world, nationwide, prospective ...

Welcome to the Journal of Restorative Reproductive Medicine, the official journal of the International Institute for Restorative Reproductive Medicine! JRRM is a peer-reviewed, open-access medical jou...

Black/African American individuals face twice the risk of hypertension compared to non-Hispanic Whites in the United States (US). A synergistic strategy integrating primary care with Electronic Health...

Objective: To determine whether endometriosis typology, namely ovarian endometriomas (OE), deep infiltrating endometriosis (DIE), or superficial endometriosis (SE), correlates with fertility history. ...

# National Patient Survey 2024 Survey of UK fertility patients: 2 September - 9 October 2024 Published: March 2025 [Download the underlying dataset as .xlsx](https://www.hfea.gov.uk/media/vf5bxixp/nat...

BACKGROUND: For more than three decades, the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) has provided a framework to quantify health loss due to diseases, injuries, and associate...

OBJECTIVE: To evaluate the outcomes of embryo donation compared with those of double gamete donation with cryopreserved donor oocytes. DESIGN: Retrospective cohort study. SUBJECTS: The 2016-2019 Soc...

BACKGROUND: Timely and comprehensive analyses of causes of death stratified by age, sex, and location are essential for shaping effective health policies aimed at reducing global mortality. The Global...

BACKGROUND: Reproductive tract disorders are increasingly recognized in aging captive cheetahs (Acinonyx jubatus), a species listed as vulnerable by the International Union for Conservation of Nature....

BACKGROUND: Endometrial hepatoid adenocarcinoma (HAC) is an exceedingly rare tumor. Histologically, the tumor is predominantly characterized by HAC with additional components, as documented in previou...

INTRODUCTION: Attention-Deficit/Hyperactivity Disorder (ADHD) in girls and women is under-recognised and under-researched, despite increasing awareness of clinical challenges and unmet needs. This rev...

Influential guidelines have supported the role of metformin in the management of polycystic ovary syndrome (PCOS) for a number of years. However, regulatory approvals for this therapeutic indication a...

BACKGROUND: Women are highly motivated and receptive to accepting family planning methods during the antenatal period. Hence, we conducted this study to evaluate the refusal rate and reasons for the r...

The human menopause is hypothesized to be an adaptive trait that allows post-reproductive females to invest in, and avoid reproductive conflict with, their existing offspring and grand-offspring, ther...