Adediran E et al.2025
Open Access
Oxford Open Digital Health
Black/African American individuals face twice the risk of hypertension compared to non-Hispanic Whites in the United States (US). A synergistic strategy integrating primary care with Electronic Health...
Hypertension ManagementDigital Health InterventionsmHealth EHR Integration
Objective: To determine whether endometriosis typology, namely ovarian endometriomas (OE), deep infiltrating endometriosis (DIE), or superficial endometriosis (SE), correlates with fertility history.
...
Typology and StagingInfertility RiskEndometriosis Staging
Upadhye JJ et al.2025Journal of family medicine and primary care
BACKGROUND: Women are highly motivated and receptive to accepting family planning methods during the antenatal period. Hence, we conducted this study to evaluate the refusal rate and reasons for the r...
Prostaglandin E2 (PGE2) is a key driver of endometriosis pathogenesis. Vipoglanstat selectively inhibits mPGES-1 enzyme activity. A Phase I trial involved 72 healthy volunteers receiving single or rep...
Ahsan M et al.2025The Indian journal of medical research
Background & objectives Polycystic ovary syndrome (PCOS) is a common endocrinopathy characterised by menstrual irregularities, hirsutism, acne, obesity, infertility, and other features adversely affec...
Brand KM et al.2025Women's health (London, England)
Influential guidelines have supported the role of metformin in the management of polycystic ovary syndrome (PCOS) for a number of years. However, regulatory approvals for this therapeutic indication a...
BACKGROUND: Endometrial cancer (EC) is one of the most common cancers in women, with a short overall survival and poor prognosis. Besides the biologically aggressive EC properties, Cancer-associated c...
STUDY QUESTION: What are the effects of three-times-a-day 10 mg oral dydrogesterone (DYD), initiated in the late follicular phase of natural menstrual cycles to induce endometrial receptivity for froz...
Farris M et al.2025Expert review of clinical pharmacology
INTRODUCTION: Pincus and his group's initial research on hormonal contraception focused on progesterone. However, the natural compound could not be utilized in clinical practice because of the high in...
ABSTRACTBackgroundChronic prurigo (CP) is a condition characterised by chronic pruritus and pruriginous lesions. While frequently associated with atopic dermatitis (AD), its link with allergic contact...
Kanbak AR et al.2025Revista da Associacao Medica Brasileira (1992)
OBJECTIVE: The aim of this study was to investigate the effect of vaginal progesterone used to prevent spontaneous preterm birth in the development of gestational diabetes mellitus.
METHODS: This is ...
STUDY QUESTION: What were the rates of utilization, effectiveness, and safety for assisted reproductive technology (ART) throughout the world in 2017 and 2018, and what trends were observed?
SUMMARY ...
Malcom CA et al.2025Journal of assisted reproduction and genetics
PURPOSE: Prior studies in fresh embryo transfer IVF cycles have associated elevated serum progesterone level on day of ovulatory trigger, particularly if ≥ 1.5 ng/ml, with decreased pregnancy rates. A...
GBD 2023 Disease and Injury and Risk Factor Collaborators2025Lancet (London, England)
BACKGROUND: For more than three decades, the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) has provided a framework to quantify health loss due to diseases, injuries, and associate...
Delanerolle G et al.2025Academia Mental Health and Well-Being
Background: Polycystic ovary syndrome (PCOS) is a common, chronic gynaecological condition impacting women of reproductive age. Women with PCOS have hormonal, ovulatory, and metabolic dysfunction resu...
Michaelsen MP et al.2025BJOG: An International Journal of Obstetrics and Gynaecology
OBJECTIVE: To study the association between previous use of levonorgestrel intrauterine system (LNG-IUS) and endometrial thickness (EMT) in women undergoing in vitro fertilisation (IVF)/intracytoplasm...
The human menopause is hypothesized to be an adaptive trait that allows post-reproductive females to invest in, and avoid reproductive conflict with, their existing offspring and grand-offspring, ther...
Abstract
Per- and polyfluoroalkyl substances (PFAS), previously known as perfluorinated compounds (PFC), are a group of synthetic chemicals widely used over the past decades. Their extensive...
BACKGROUND: Endometrial hepatoid adenocarcinoma (HAC) is an exceedingly rare tumor. Histologically, the tumor is predominantly characterized by HAC with additional components, as documented in previou...
DIR Jahrbuch 2024 des Deutschen IVF-Registers. ENGLISH SUMMARY: 2024 Annual Report of the German IVF Registry (Deutsches IVF-Register, DIR). Reports German ART cycle counts, treatment indications, emb...
GBD 2023 Causes of Death Collaborators2025Lancet (London, England)
BACKGROUND: Timely and comprehensive analyses of causes of death stratified by age, sex, and location are essential for shaping effective health policies aimed at reducing global mortality. The Global...
OBJECTIVE: To evaluate the outcomes of embryo donation compared with those of double gamete donation with cryopreserved donor oocytes.
DESIGN: Retrospective cohort study.
SUBJECTS: The 2016-2019 Soc...
Per- and polyfluoroalkyl substances (PFAS) are synthetic chemicals widely used in consumer and industrial products due to their unique physicochemical properties. However, their persistence and bioacc...
BACKGROUND: Endometriosis affects approximately 10% of women of reproductive age and is associated with increased risks of infertility and miscarriage. Although the spontaneous miscarriage rate in wom...
Per- and polyfluoroalkyl substances (PFASs) have been widely used in the production of consumer products globally due to the excellent water and oil resistance and anti-fouling properties. The multipl...
Nationwide survey of JSOG-registered ART facilities on perceptions of disclosing institutional success rates for IVF. Provides context for the JSOG registry's reporting model and clinic-level transpar...
1. Define premature ovarian insufficiency, diagnostic criteria, risk factors and comorbidities.
2. Discuss health concerns, as well as health and hormone management of patients suffering with POI.
3. ...
Canadian Fertility and Andrology Society et al.2025Canadian Fertility and Andrology Society - CARTR Plus
CARTR Plus 2025 annual report covering Canadian ART activity for treatment cycles completed in 2024. Reports cycles performed, single-embryo transfer rates, clinical pregnancy and live-birth rates, AR...
# National Patient Survey 2024
Survey of UK fertility patients: 2 September - 9 October 2024
Published: March 2025
[Download the underlying dataset as .xlsx](https://www.hfea.gov.uk/media/vf5bxixp/nat...
Sweden national IVF registry report covering 2023 treatments. 26,500 treatments started at 23 clinics (6 public, 17 private). 5,804 live born children (5,508 IVF + 296 IUI-D). Fresh IVF delivery rate ...
BACKGROUND: Reproductive tract disorders are increasingly recognized in aging captive cheetahs (Acinonyx jubatus), a species listed as vulnerable by the International Union for Conservation of Nature....
INTRODUCTION: Among the religious factors that significantly contribute to believers' well-being, research on the personal experience of divine forgiveness (DF) remains in its infancy. The aim of this...
Tian W et al.2025Journal of Colloid and Interface Science
Transition-metal phosphates/phosphides showcase significant promise for energy-related applications because of their high theoretical electrochemical characteristics. However, sluggish electro/ion tra...
PURPOSE: To evaluate the effectiveness and safety of the novel protocol-progestin-primed ovarian stimulation (PPOS) protocol during controlled ovarian hyperstimulation (COH), in patients undergoing in...
Ovarian hyperstimulation syndrome (OHSS) is a serious complication commonly encountered in patients with infertility undergoing ovulation induction therapy. This study investigates histomorphological ...
Kooij JJS et al.2025Frontiers in global women's health
INTRODUCTION: Attention-Deficit/Hyperactivity Disorder (ADHD) in girls and women is under-recognised and under-researched, despite increasing awareness of clinical challenges and unmet needs. This rev...
INTRODUCTION: Insulin resistance and hyperinsulinaemia significantly influence female hormone regulation and reproductive health. Despite increasing research, the complex pathways by which nutritional...
INTRODUCTION: The design and functionality of injection devices for controlled ovarian stimulation (COS) significantly influence dose accuracy and patient comfort, affecting adherence and treatment su...
BACKGROUND: Intrauterine insemination (IUI) is the first line treatment for conditions such as unexplained or mild male factor infertility. Endometrial thickness (EMT) is an important indicator for pr...
During early pregnancy, human endometrial stromal cells differentiate into secretory decidual cells via a process regulated by ovarian steroid hormones. Decidual cells play a crucial role by secreting...