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Current strategies for the assessment and treatment of recurrent pregnancy loss are discussed. This replaces the previous document, titled, "Evaluation and treatment of recurrent pregnancy loss: a com...

BACKGROUND: The human placenta consumes, on average, one third of the glucose from maternal blood. However, the role of placental glucose consumption in the production of estradiol and progesterone re...

PURPOSE: Adenomyosis is a chronic uterine disorder characterised by ectopic endometrial tissue within the myometrium, frequently associated with dysmenorrhea, abnormal uterine bleeding (AUB), chronic ...

This secondary analysis examined two independent U.S. surveys (J.L. Partners, N=1002; McLaughlin & Associates, N=1000) investigating public perspectives on fertility treatments. Initial support for IV...

IMPORTANCE: Restorative Reproductive Medicine (RRM) aims to restore fertility by diagnosing and treating the underlying causes of infertility. RRM is frequently promoted as an alternative to assisted ...

Endometriosis is an estrogen-dependent inflammatory disorder frequently associated with infertility and characterized by progesterone resistance and impaired endometrial receptivity. While ectopic les...

BACKGROUND: Migraine is a neurologic disorder that disproportionately affects women and undergoes important changes across the menopausal transition. Estrogen fluctuations contribute to migraine expre...

Objective: To evaluate the extent to which a history of infertility is associated with adherence to specific diets among reproductive-aged females. Design: Cross-sectional analysis. Subjects: Between ...

Background Polycystic ovary syndrome (PCOS) is a heterogeneous endocrine-metabolic disorder characterized by reproductive, hormonal, and metabolic disturbances. This study aimed to evaluate the associ...

INTRODUCTION: Postvasectomy pain syndrome (PVPS) is a poorly understood, chronic condition affecting up to 5% of men post vasectomy. With limited evidence guiding its management, vasectomy reversal (V...

Polycystic ovary syndrome (PCOS) is the most common endocrine disorder among women of reproductive age, typically characterized by irregular menstrual cycles. Our study found that postpartum menstrual...

Background: Endometriosis has been linked to cardiometabolic alterations, but whether these associations vary by disease severity or phenotype is unclear. We examined lipid profiles across endometrios...

Objective: To examine birth outcomes between children conceived with in vitro fertilization (IVF) or intrauterine insemination (IUI) and sibling births from unassisted conceptions. Design: Retrospect...

For many patients with endometriosis, laparoscopic surgery is the most effective treatment to alleviate severe chronic pelvic pain and improve quality of life. Because endometriosis is common among in...

This systematic review and meta-analysis examined the relationship between menstrual cycle phases and the incidence of muscle injuries in female team sport athletes, following PRISMA 2020 and PERSiST ...

Infertility affects 1 in 6 people globally (and up to a third of physicians) and is recognized by the World Health Organization and the American Medical Association as a disease. Since 1978, the devel...

Background: Endometriosis is a chronic, gynecologic condition in which tissue similar to the lining of the uterus implants throughout the body. Women with endometriosis have a higher prevalence of inf...

STUDY OBJECTIVE: To study whether bilateral nonpatency of fallopian tubes is correlated with a lower recurrence rate of endometriosis. DESIGN: Retrospective 2:1 matched case-control study. SETTING: Un...

Objective: Disordered eating behaviors may impact the gynecologic health of adolescents through effects on menstrual cycle function and body size; however, few studies have evaluated these association...

Normal uterine function depends on cyclical regeneration and the capacity to sustain pregnancy. A cesarean incision represents an injury to this remarkable organ. Although the uterus possesses excepti...

Peipert et al. (1) claim that restorative reproductive medicine (RRM) originated as a political and religious movement with the purpose to limit access to in vitro fertilization (IVF). In so doing, th...

OBJECTIVE: This debate paper aims to examine the effects of glucagon-like peptide-1 receptor agonists (GLP-1 RAs), whose use in obesity and diabetes management has rapidly expanded, on fertility, cont...

INTRODUCTION: Vulvodynia is a chronic vulvar pain condition significantly affecting the quality of life. Its multifactorial etiology is not fully understood, and comprehensive pooled data on associate...

BACKGROUND: Down's syndrome (DS) is the most common chromosomal congenital condition diagnosed in pregnancy. Antenatal screening for DS is available in Scotland, and in September 2020, non-invasive pr...

A portable, universal, easy-to-preserve alternative of human red blood cells (RBC) has been pursued for decades in order to expand the limited blood supply, with Hemoglobin-Based Oxygen Carrier (HBOC)...

Curcumin, a bioactive polyphenol derived from turmeric (Curcuma longa), has garnered substantial attention for its potent anti-inflammatory, antioxidant, and antineoplastic properties. This review exp...

Serum progesterone (P) levels are critical for endometrial receptivity and implantation in frozen-thawed embryo transfer (FET) cycles. However, the prognostic role of P levels measured on the day of t...

Ursolic Acid (UA), a naturally occurring pentacyclic triterpene, was isolated from Ochrosia elliptica. Polycystic Ovary Syndrome (PCOS) a prevalent endocrine disorder characterized by hyperandrogenism...

BACKGROUND: Postpartum depression (PPD) affects 10% to 20% of mothers, with higher rates among marginalized communities. Mental health issues contribute to 22.7% of pregnancy-related deaths. Doulas pr...

BACKGROUND: Social Egg Freezing (SEF), often promoted in Western contexts as a means to enhance reproductive autonomy, has seen varied uptake in countries with wider gender disparities. In such settin...

Spermatogenesis relies on the intricate interactions between testicular somatic cells and germ cells. While follicle-stimulating hormone (FSH) and testosterone (T) are considered pivotal regulatory fa...

Objectives. To quantify the impact of state abortion bans on trends in fertility and preterm birth following the June 2022 US Supreme Court decision in Dobbs v Jackson Women's Health Organization. Met...

INTRODUCTION: Hyperbaric oxygen therapy (HBOT) is used for various medical conditions. HBOT is demanding and varies in effectiveness. This intensity combined with logistical challenges may lead to pat...

BACKGROUND: Denmark's publicly funded routine HPV vaccination program has included boys born from 2005 onward, leaving earlier birth cohorts of young men potentially unprotected. METHODS: A published...

OBJECTIVE: To assess the combined role of prenatal imaging and stepwise genetic testing in diagnosing fetal congenital heart defects (CHDs) over a 30-year period, focusing on CHD subtypes, extracardia...

BACKGROUND: Healthcare professionals' and students' willingness to provide abortion influences access to care and workforce readiness. OBJECTIVE: We conducted a literature synthesis to identify patte...

Regular welfare assessments are essential for identifying and addressing the physical, behavioral, and emotional needs of shelter dogs, thereby ensuring their well-being and improving chances for adop...

STUDY QUESTION: Is there a difference in live birth rates at 24 months between infertile women with polycystic ovary syndrome (PCOS) who have normal versus abnormal glucose metabolism? SUMMARY ANSWER...

OBJECTIVES: Congenital uterine anomalies are the result of abnormal development of the Müllerian ducts and occur in approximately 5% of the general female population. These malformations often remain ...

PURPOSE: To evaluate the clinical relevance of serum progesterone levels on the day of frozen embryo transfer (FET) and the dose of vaginal progesterone gel (Crinone) used for early luteal phase suppo...