Therapeutics · Emerging Therapies

Effects of 660-nm Photobiomodulation Therapy on Pain and Healing of Nipple Trauma in Lactating Women: A Pilot Randomized Double-Blind Controlled Trial

Moraes BHM, Rocha HC, Melo MSF, Xavier DM, Baracho VdS, Oliveira MX

Research Square (preprint), 2026
DOI 10.21203/rs.3.rs-10362193/v1

Abstract

Objective

To evaluate the effects of PBMT (λ = 660 nm) on pain, breastfeeding quality, and healing of nipple injuries.

Method

This randomized, double-blind, controlled pilot trial included 20 lactating postpartum women with nipple trauma. Participants were divided into PBMT (standard care + active PBMT) and Placebo (standard care + sham) groups. Interventions occurred up to seven sessions over 15 days. PBMT parameters: 660 nm, 40 mW, 10 J/cm², and 0.4 W/cm² for 10s per point (one central and four peripheral points). Assessments included the Visual Analogue Scale (VAS), LATCH Scale, Nipple Trauma Score (NTS), and photogrammetry.

Results

Most participants (90%) presented bilateral excoriations or fissures. The PBMT group showed significantly greater pain reduction from the third session onward (p < 0.05), achieving total analgesia by the seventh, whereas the Placebo group maintained higher VAS scores. Although both groups improved their breastfeeding technique, the PBMT group showed superior post-intervention LATCH scores. Furthermore, PBMT significantly accelerated tissue repair from the third session onward. The PBMT group reached complete lesion regression (NTS = 0), while the Placebo group maintained residual trauma (NTS = 1).

Conclusion

PBMT combined with clinical management is effective for pain relief, tissue repair, and improving breastfeeding quality. It serves as a promising adjuvant resource to prevent complications and support the maintenance of exclusive breastfeeding.

Topics

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Therapeutics › Emerging Therapies › Light Therapy · Postpartum › Infant Feeding › Breastfeeding Support · General Gynecology › Breast Health › Benign Breast Conditions
Bruna Heloísa Miranda de Moraes, Helenice Cordeiro Rocha, Marcela Soares França Melo, Diêgo Mendes Xavier, Murilo Xavier Oliveira
B Moraes, H Rocha, M Melo, D Xavier, M Oliveira
DOI 10.21203/rs.3.rs-10362193/v1 10.21203/rs.3.rs-10362193/v1 Moraes et al. 2026, Moraes 2026