# Fertility treatment 2023: trends and figures
Preliminary UK statistics for IVF and DI treatment, storage, and donation
Published: June 2025
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IVF Outcomes and StatisticsFrozen Embryo TransferPopulation-Level Data
Some medical professional organizations have advocated for including the menstrual cycle as a vital sign in adolescence, but not in adulthood. However, documenting menstrual cycle patterns is not rout...
Palmore M et al.2025
Open Access
Environmental epigenetics
Prenatal exposure to air pollution is an important risk factor for child health outcomes, including asthma. Identification of DNA methylation changes associated with air pollutant exposure can provide...
Air Pollution EpigeneticsAsthma and Allergy RiskDNA Methylation
Importance: Identifying atypical body mass index (BMI) trajectories in children and understanding associated, modifiable early-life factors may help prevent childhood obesity.
Objective: To character...
Mortazavi V et al.2025
Open Access
BMC Oral Health
A cell-free particulate enzyme preparation of Mycobacterium smegmatis ATCC 607 catalyzed the transfer of labeled mannose from GDP[14C] mannose to methyl-alpha-D-mannopyranoside (an exogenously added a...
Background: Ovarian hormones affect cardiovascular health yet few sufficient-sized studies with reliable ovulatory documentation have assessed the QTc-hormonal relationship. This study investigated QT...
Breast tenderness and swelling are associated with premenstrual symptoms but are not well described in healthy women. In this 1-year prospective observational study, we examined daily breast tendernes...
The use of hormonal treatments for endometriosis has increased in recent years. Their effectiveness lies in creating a stable hormonal environment, reducing peripheral estrogen levels, and suppressing...
Several studies have associated seminal microbiota abnormalities with male infertility but have yielded differing results owing to their limited sizes or depths of analyses. The semen microbiota durin...
Importance: Medical gaslighting, in which a patient's concerns are dismissed without proper evaluation, has been described anecdotally in vulvovaginal patient care, but has not been quantified.
Objec...
Patient ExperienceGaslighting and DismissalVulvovaginal Conditions
Objectives: This study aimed to elucidate the effects of messenger RNA (mRNA) and inactivated coronavirus disease 2019 (COVID-19) vaccines on ovarian histology and reserve in rats.
Methods: Thirty fe...
Davis CP et al.2025Human Reproduction (Oxford, England)
STUDY Question: Are dietary patterns associated with age at menarche after accounting for BMI-for-age (BMIz) and height?
SUMMARY ANSWER: We observed associations between both the Alternative Healthy ...
Bouchard T et al.2025
Open Access
Journal of Restorative Reproductive Medicine
Objective: There is considerable individual day-to-day variation within the menstrual cycle and between cycles in women. Average hormone curves inadequately describe the individual hormone patterns ex...
Objectives: The objective of this study is to test the association between preconception polycystic ovary syndrome (PCOS) and gestational diabetes mellitus (GDM) using Utah's Pregnancy Risk Assessment...
Gestational DiabetesMetabolic DisordersPCOS and Pregnancy Risk
Urtica dioica is widely distributed across temperate regions of the world and is highly beneficial and packed with nutritional value including a rich profile of phytochemicals, amino acids, and essent...
Traditionally, taste receptors (TRs) have been understood to reside within the taste buds on the tongue, serving as initiators for different taste perceptions. However, recent research has expanded ou...
Chung HF et al.2025
Open Access
Human Reproduction (Oxford, England)
STUDY Question: What is the association between endometriosis and the type and age of menopause?
SUMMARY ANSWER: Women with endometriosis had a 7-fold increased risk of undergoing surgical menopause ...
There is growing interest in the use of microbial-seeding interventions to mitigate the impacts of prenatal antibiotics, C-section, and lack of breastfeeding on mother-child microbe sharing. However, ...
Maternal-Infant TransmissionGut Health DevelopmentECHO Microbiome
Yeung P2025
Open Access
Journal of Restorative Reproductive Medicine
Restorative reproductive surgery has emerged to become an exciting and promising field of surgery that can transform the way that we treat patients, especially regarding fertility. As a prime example ...
The gut microbiome influences the metabolism and health of several organs beyond the gut and has recently gained considerable attention. The gut plays a central role in food digestion, absorption, nut...
Testosterone MetabolismMicrobiome InfluenceMale Reproductive Health
Senthilkumar H et al.2025Journal of translational medicine
Polycystic ovary syndrome (PCOS) is an endocrine disorder that affects reproductive-aged women worldwide, causing hormonal imbalances and ovarian dysfunction. PCOS affects metabolic health and increas...
Arraztoa JA2025
Open Access
Journal of Restorative Reproductive Medicine
In 1972, a seminal article was published demonstrating that women, adequately trained, could detect the approach of ovulation in the fertile window of their menstrual cycle. It was demonstrated that t...
Textile products contain various chemicals, making safety evaluation complex. We conducted an exploratory investigation of aryl hydrocarbon receptor (AhR) agonists in textile products using effect-dir...
Chen TY et al.2025Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
OBJECTIVE: Despite certain studies indicating hearing impairments in individuals with polycystic ovary syndrome (PCOS), the correlation between PCOS and sensorineural hearing loss (SNHL) remains incon...
Fang R et al.2025
Open Access
Aerosol and Air Quality Research
Background Low-cost sensors (LCS) are widely used for air quality monitoring, but their accuracy depends on proper calibration. This study compares linear regression (LR) and machine learning (ML) tec...
Bouchard TP et al.2025
Open Access
Women's health reports (New Rochelle, N.Y.)
Background: Measuring quantitative menstrual cycle hormones at home may help women better understand their postpartum and perimenopause fertility transitions, but these quantitative fertility monitors...
Ectopic pregnancy occurs when a fertilized egg implants outside the uterine cavity, a condition that affects approximately 1% to 2% of pregnancies in the United States. Ectopic pregnancy is a potentia...
Frey Nascimento A et al.2025
Open Access
BMJ Evidence-based Medicine
Objective: To investigate the efficacy and safety of open-label placebos (OLP) in premenstrual syndrome (PMS).
Design: Randomised controlled trial.
Setting: Switzerland, 2018-2020.
Participants: 150 ...
Davenport MH et al.2025British journal of sports medicine
This consensus aims to provide guidance for postpartum women and people, healthcare providers and exercise professionals on physical activity, sedentary behaviour and sleep throughout the first year p...
Deneer JJM et al.2025
Open Access
Reproductive Sciences
Four possible metabolic approaches to improving cardiac function in the presence of myocardial hypoxia have been considered. 1. It appears that there is increasing evidence which suggests that free fa...
BACKGROUND: Antiphospholipid syndrome (APS) is an autoimmune disorder associated with thrombotic events and adverse obstetric outcomes, particularly in its obstetric form (OAPS). Affecting approximate...
Bragg MG et al.2025
Open Access
The Journal of Nutrition
Background: Previous research on the role of maternal diet in relation to autism has focused on examining individual nutrient associations. Few studies have examined associations with multiple nutrien...
Neurodevelopmental DisordersMaternal Diet and Child HealthMixtures Analysis
Introduction: Endometriosis, affecting 11% of reproductive-aged persons, is characterized by ectopic endometrial tissue and chronic inflammation. Prior research suggests those with endometriosis have ...
Inflammatory MarkersStaging and TypologyCytokine Profiling
Background:
Individuals with endometriosis, a gynecologic condition affecting approximately 11% of people with a uterus, may have an elevated risk for developing cardiovascular disease (CVD) later in ...
Cardiovascular RiskStaging and TypologyLipid Biomarkers
Mayo Clinic patient overview of vasectomy, a permanent male contraceptive procedure that cuts and seals the vas deferens. Covers indications, the no-scalpel technique, risks, recovery, and semen testi...
Tapia-Pizarro A et al.2025Reproduction (Cambridge, England)
IN BRIEF: Progesterone supplementation reverses 83% of transcript changes in the secretory endometrium induced by postovulatory mifepristone, potentially mitigating its antiprogestogenic effects. ABST...
Self-reported dietary intake varies across menstrual cycle phases, but objective assessments of dietary intake together with appetite and resting metabolic rate (RMR) are limited. This study aimed to ...
Lyall K et al.2025Autism research : official journal of the International Society for Autism Research
Prevalence of autism diagnosis has historically differed by demographic factors. Using data from 8224 participants drawn from the Environmental influences on Child Health Outcomes (ECHO) Program, we e...
Combined oral contraceptives (COCs) possess the ability to alter the normal composition of the gut microbiome and the permeability of the gastrointestinal (GI) tract, which may cause both gut-related ...
Brito J et al.2025Journal of applied physiology (Bethesda, Md. : 1985)
Understanding changes to gut microbiota composition in response to hormonal birth control (HBC) may provide insight into the microbial mechanisms underlying the metabolic effects of HBC, for example, ...
Yonis H et al.2025
Open Access
BMJ (Clinical Research Ed.)
Objective: To evaluate the association between contemporary hormonal contraceptive use and the risk of incident ischaemic stroke and myocardial infarction.
Design: Real-world, nationwide, prospective ...
Stanford JB2025
Open Access
Journal of Restorative Reproductive Medicine
Welcome to the Journal of Restorative Reproductive Medicine, the official journal of the International Institute for Restorative Reproductive Medicine! JRRM is a peer-reviewed, open-access medical jou...
Restorative Reproductive Medicine OverviewDefinition and FrameworkBiomarker-Based Medical Evaluation
Garmendia JV et al.2025International journal of molecular sciences
Recurrent pregnancy loss (RPL) is defined as the occurrence of two or more consecutive pregnancy losses before 24 weeks of gestation. It affects 3-5% of women who are attempting to conceive. RPL can s...
Zhang S et al.2025American journal of preventive medicine
INTRODUCTION: Polycystic ovary syndrome is associated with hypertension in women, but few population studies have examined findings among adolescents. This retrospective study examines PCOS and hypert...