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The Billings method of family planning: an assessment

Betts K, 1984 Studies in Family Planning

The Billings/ovulation method is a periodic abstinence method of regulating births based on the client's interpretation of changing patterns in secretions of cervical mucus monitored by external self-...

Fertility Awareness > Billings Ovulation Method > EffectivenessFertility Awareness > Billings Ovulation Method > Physiological BasisFertility Awareness > Program Evaluation > Acceptability

Intrauterine contraception with copper and with levonorgestrel: a randomized study of the TCu 380Ag and levonorgestrel 20 mcg/day devices

Sivin I et al., 1984 Contraception

First year results of a randomized study of 1509 users of the Copper T380Ag with a silver core or of an IUD releasing 20 mcg day of levonorgestrel are reported. The cumulative gross pregnancy rate for...

Contraception/Comparison > Intrauterine Devices > Copper vs Hormonal IUDContraception/Comparison > Side Effects > Bleeding and AmenorrheaResearch Methodology > Randomized Controlled Trials > Contraceptive Devices

Endometriosis and corpus luteum function. Is there a relationship?

Pittaway DE et al., 1984 The Journal of Reproductive Medicine

More than 100 years after the first description of endometriosis, the pathophysiology of the disorder still remains an enigma. In addition to infertility, an increased frequency of clinically apparent...

Endometriosis > Pathophysiology > Corpus Luteum DysfunctionEndometriosis > Reproductive Outcomes > Spontaneous AbortionInfertility > Endometriosis > Prostaglandin-Mediated Mechanisms

The effect of medroxyprogesterone acetate (Depo-Provera) on prenatal development in the baboon (Papio anubis): a preliminary study

Tarara R, 1984 Teratology

Six female olive baboons (Papio cynocephalus anubis) were treated with a single dose of 150 mg of Depo-Provera i.m. at day 30 of pregnancy, approximately three times the human dose equivalent on a bod...

Reproductive Endocrinology > Progestogens > Fetal EffectsContraception/Comparison > Injectable Contraceptives > Safety in PregnancyResearch Methodology > Animal Studies > Teratology

Natural family planning in Mauritius, Indian Ocean: utilization patterns and continuance predictors

Conner GL et al., 1984 Journal of Social Service Research

Factors associated with discontinuation from an island-wide natural family planning program in Mauritius were examined in 2 stratified random samples of 300 (1976) and 350 (1980) acceptors. The data w...

Fertility Awareness > Program Evaluation > Continuation and DiscontinuationFertility Awareness > Symptothermal Method > Developing Country ProgramsFertility Awareness > Education > Educator-Client Relationship

Endocrine profiles in tamoxifen-induced conception cycles

Tajima C, 1984 Fertility and Sterility

Twenty-five infertile women conceived while taking tamoxifen (TMX). Daily serum profiles of 5 of the 25 TMX-induced conception cycles were elucidated and compared with those found in 5 normal cycles. ...

Infertility > Ovulation Induction > TamoxifenReproductive Endocrinology > Hormonal Profiles > Conception CyclesInfertility > Medical Management > Anti-Estrogen Therapy

Causes of preterm delivery

Gravett MG, 1984 Seminars in Perinatology

Although major advances have been made in both obstetric care of the high-risk patient and in neonatal care, prematurity and its consequences remain the major contributor to perinatal mortality. The i...

Pregnancy > Preterm Birth > Etiology and Risk FactorsPregnancy > Complications > Genital InfectionsGeneral OB/GYN > High-Risk Pregnancy > Preterm Delivery Prevention

Induction of ovulation with an estrogen antagonist, tamoxifen

Tsuiki A et al., 1984 The Tohoku Journal of Experimental Medicine

Tamoxifen (Norvadex), synthesized by the Imperial Chemical Industries Ltd., is a triphenylethylene derivative having a clomiphene-like structure and displays anti-estrogenic activities. In this study ...

Infertility > Ovulation Induction > TamoxifenInfertility > Ovulation Induction > Anti-Estrogen TherapyReproductive Endocrinology > Pharmacology > Estrogen Antagonists

Reduced frequency of pulsatile luteinizing hormone secretion in the luteal phase of the rhesus monkey. Involvement of endogenous opiates

Van Vugt DA et al., 1984 Endocrinology

Pulsatile secretion of LH in women has been shown to vary during the menstrual cycle. LH pulse frequency during the luteal phase is markedly reduced compared to that in the follicular phase. The objec...

Reproductive Endocrinology > Gonadotropin Regulation > LH PulsatilityMenstrual Cycle > Luteal Phase > Neuroendocrine RegulationReproductive Endocrinology > Neuroendocrinology > Opioid Modulation

Preliminary results on the scanning electron microscopic structure of infertile human cervical mucus

Faccioli G, 1984 Acta Europaea Fertilitatis

Interesting data on infertile human membranous mucus compared with infertile filamentous mucus have emerged from previous studies using scanning electron microscopy (SEM). The aim of this study was to...

Fertility Awareness > Cervical Mucus > UltrastructureDiagnostics > Cervical Mucus Analysis > Scanning Electron MicroscopyMenstrual Cycle > Follicular Phase > Cervical Mucus Changes

Antiestrogenic effect of clomiphene citrate: correlation with serum estradiol concentrations

Maxson WS et al., 1984 Fertility and Sterility

The antiestrogenic effect of clomiphene citrate (CC) on cervical mucus was evaluated in women receiving 150 mg CC daily for 5 days. Daily cervical mucus scores and serum estradiol (E2) concentrations ...

Infertility > Ovulation Induction > Clomiphene Citrate Side EffectsFertility Awareness > Cervical Mucus > Hormonal InfluencesReproductive Endocrinology > Pharmacology > Anti-Estrogenic Effects

Canalization of human cervical mucus

Garcea N et al., 1984 Obstetrics and Gynecology

Cervical mucus forms channels when dried under a coverslip. The aim of the present work was: 1) to prove mucus canalization both in spontaneous ovulatory cycles and during ovulation induction with gon...

Fertility Awareness > Cervical Mucus > Canalization PhenomenonDiagnostics > Cervical Mucus Analysis > Ferning and Channel FormationInfertility > Ovulation Induction > Monitoring Methods

Luteotropic effects of tamoxifen in infertile women

Tajima C, 1984 Fertility and Sterility

Tamoxifen at a dose of 10 mg/day for 5 days was given to five infertile women in the luteal phase. Daily serum samples were obtained during the luteal phase for radioimmunoassay of progesterone (P), e...

Reproductive Endocrinology > Luteal Phase > Pharmacological SupportInfertility > Luteal Phase Defect > Tamoxifen TreatmentReproductive Endocrinology > Pharmacology > Anti-Estrogen Luteotropic Effects

A randomized controlled trial of cervical cerclage in women at high risk of spontaneous preterm delivery

Rush RW et al., 1984 British Journal of Obstetrics and Gynaecology

The effect of cervical suture on pregnancy outcome was studied in 194 women with a high risk (approximately 30%) of having a late abortion or a preterm delivery. The women were randomly allocated eith...

Pregnancy > Preterm Birth Prevention > Cervical CerclagePregnancy > Cervical Incompetence > Surgical InterventionResearch Methodology > Randomized Controlled Trials > Obstetric Interventions

Retrograde menstruation in healthy women and in patients with endometriosis

Halme J et al., 1984 Obstetrics and Gynecology

Blood was found in the peritoneal fluid in 90% of women with patent tubes at laparoscopy during perimenstrual time. If the fallopian tubes were occluded, then only 15% of patients had evidence of bloo...

Endometriosis > Pathogenesis > Retrograde MenstruationMenstrual Cycle > Menstruation > Retrograde FlowGeneral OB/GYN > Laparoscopy > Peritoneal Fluid Findings

Silent chorioamnionitis as a cause of preterm labor refractory to tocolytic therapy

Hameed C et al., 1984 American Journal of Obstetrics and Gynecology

Thirty-seven consecutive patients with singleton pregnancies in "uncomplicated" preterm labor with intact membranes suitable for tocolysis were evaluated for evidence of silent chorioamnionitis by mea...

Pregnancy > Preterm Birth > Subclinical ChorioamnionitisPregnancy > Preterm Labor > Tocolysis FailureDiagnostics > Infectious Markers > Amniotic Fluid Analysis

Multicentred controlled trial of cervical cerclage in women at moderate risk of preterm delivery

Lazar P et al., 1984 British Journal of Obstetrics and Gynaecology

A total of 506 women at moderate risk of preterm delivery were randomly allocated to either cervical cerclage or a control group. Significantly more women in the group allocated to cerclage were admit...

Pregnancy > Preterm Birth Prevention > Cervical CerclageResearch Methodology > Randomized Controlled Trials > Multicenter StudiesPregnancy > Cervical Incompetence > Cerclage Effectiveness

Normal variation in the length of the luteal phase of the menstrual cycle: identification of the short luteal phase

Lenton EA et al., 1984 British Journal of Obstetrics and Gynaecology

Normal probability plots were used to assess the homogeneity of a population of 327 luteal phases from apparently ovulatory menstrual cycles. The length of the luteal phase was defined as the interval...

Menstrual Cycle > Luteal Phase > Normal VariationMenstrual Cycle > Luteal Phase > Short Luteal PhaseDiagnostics > Luteal Phase Assessment > Luteal Phase Length

Use-effectiveness of fertility awareness among the urban poor

Dorairaj K, 1984 Social Action

The efficacy, the ability of Indian women to use the Billings' Ovulation Method, and its effectiveness in helping them to control their fertility was studied in a sample of urban poor living in the De...

Fertility Awareness > Billings Ovulation Method > Use-EffectivenessFertility Awareness > Natural Family Planning > Developing CountriesBody Literacy > Cervical Mucus Observation > Fertility Identification

Endometriosis and spontaneous abortion

Groll M, 1984 Fertility and Sterility

There seems to be an association of first-trimester spontaneous abortion and untreated endometriosis. In this report, 52% of an untreated group of patients with endometriosis aborted. However, 12% of ...

Endometriosis > Pregnancy Outcomes > Spontaneous AbortionEndometriosis > Treatment > Medical and Surgical TherapyPregnancy > Complications > Recurrent Pregnancy Loss

A randomized study of dexamethasone in ovulation induction with clomiphene citrate

Daly DC et al., 1984 Fertility and Sterility

Improved understanding of follicular dynamics has led to a reevaluation of suppression of adrenal androgens in ovulation induction. To test whether adrenal suppression during clomiphene citrate (CC) t...

Infertility > Ovulation Induction > Clomiphene CitrateInfertility > Ovulation Induction > Adjunctive DexamethasoneReproductive Endocrinology > Adrenal Androgens > DHEA-S and Ovulation

Outcome of progesterone treatment of luteal phase inadequacy

Wentz AC et al., 1984 Fertility and Sterility

Diagnosis, choice of therapy, and pregnancy outcome were analyzed in 79 women evaluated for luteal phase inadequacy. Criteria for the diagnosis were established, and groups at risk for luteal inadequa...

Infertility > Luteal Phase Defect > Progesterone TreatmentReproductive Endocrinology > Luteal Phase > Progesterone SupplementationInfertility > Luteal Phase Defect > Diagnosis and Management

Adhesion prevention by solutions of sodium carboxymethylcellulose in the rat. I

Elkins TE et al., 1984 Fertility and Sterility

Solutions of sodium carboxymethylcellulose (SCMC) were studied in rats to determine their longevity within the peritoneal cavity and their potential for prevention of postoperative intraperitoneal adh...

Surgery > Adhesion Prevention > Barrier AgentsSurgery > Adhesion Prevention > Animal ModelsInfertility > Surgical Management > Adhesion Prevention

Failure of human oocyte release at ovulation

Stanger JD et al., 1984 Fertility and Sterility

Among 150 patients admitted for ovum aspiration, in vitro fertilization, and embryo transfer in Perth, Western Australia, 14 were found to have had at least one ovulated follicle at the time of laparo...

Infertility > Ovulation Disorders > Oocyte Release FailureReproductive Endocrinology > Ovulation > Follicle Rupture DynamicsInfertility > Assisted Reproduction > IVF Oocyte Recovery

The single woman and artificial insemination by donor

Strong C et al., 1984 The Journal of Reproductive Medicine

Requests by single women for artificial insemination by donor (AID) raise important ethical issues concerning the obligations of physicians and the well-being of the children who would be conceived. S...

Ethics/Philosophy > Reproductive Ethics > Donor InseminationEthics/Philosophy > Physician Obligations > Patient Selection

Assessment and hormonal treatment of the luteal phase of in vitro fertilization cycles

Yovich JL et al., 1984 The Australian & New Zealand Journal of Obstetrics & Gynaecology

Luteal phase lengths and hormonal profiles (progesterone, oestradiol-17 beta, beta HCG and prolactin) have been documented in 77 cases derived from a series of patients undergoing IVF. Nineteen pregna...

Reproductive Endocrinology > Luteal Phase > IVF Luteal SupportInfertility > Assisted Reproduction > Luteal Phase ManagementReproductive Endocrinology > Progesterone > Luteal Phase Deficiency

The ovulation method of family planning

Muzzerall L, 1984 Canadian Family Physician Medecin De Famille Canadien

With the Billings Ovulation Method of natural family planning, women chart the symptoms of changes of their cervical mucus to determine when they are ovulating. The Ovulation Method is simple to learn...

Fertility Awareness > Billings Ovulation Method > EffectivenessFertility Awareness > Cervical Mucus Monitoring > Patient EducationBody Literacy > Cervical Mucus > Ovulation Detection

Psychiatric disorder in pregnancy and the first postnatal year

Watson JP et al., 1984 The British Journal of Psychiatry : the Journal of Mental Science

We interviewed 128 women regularly during pregnancy and the first postnatal year. Psychiatric interviews identified eight 'cases' of psychiatric disorder (6 per cent) in early pregnancy and twenty 'ca...

Pregnancy > Mental Health > Perinatal Psychiatric DisordersPostpartum > Mental Health > Postnatal DepressionPregnancy > Complications > Affective Disorders

Prolactin production from proliferative phase leiomyoma

Daly DC et al., 1984 American Journal of Obstetrics and Gynecology

In vivo and in vitro endometrial stromal synthesis of prolactin occurs after progesterone-induced decidualization. Synthesis of prolactin by myometrium in vitro suggests that cells whose embryologic o...

Reproductive Endocrinology > Prolactin > Ectopic ProductionGeneral OB/GYN > Uterine Fibroids > Prolactin SynthesisReproductive Endocrinology > Hormonal Regulation > Progesterone Effects

Hormonal bases of the correspondence between microscopic and ultramicroscopic features of human cervical mucus

Faccioli G, 1984 Acta Europaea Fertilitatis

By studying the changes of microscopic and ultramicroscopic structure of cervical mucus and the corresponding changes of ovarian hormone levels throughout the cycle, a close correspondence was found b...

Menstrual Cycle > Cervical Mucus > Ultrastructural AnalysisReproductive Endocrinology > Ovarian Hormones > Cervical Mucus EffectsBody Literacy > Cervical Mucus > Hormonal Correlates

Natural family planning in the Philippines

Laing JE, 1984 Studies in Family Planning

The calendar rhythm method of natural family planning (NFP) is one of the most popular contraceptive methods in the Philippines. As a result, the Philippines has one of the highest NFP prevalence rate...

Fertility Awareness > Calendar Rhythm Method > Program ImplementationFertility Awareness > Global Programs > Developing CountriesResearch Methodology > Program Evaluation > Family Planning

Attitudes toward the rhythm method in the Philippines

Verzosa CC et al., 1984 Studies in Family Planning

Two sets of focus group discussions on the advantages and disadvantages of the rhythm method were carried out in the Philippines in 1980 and 1981. The first discussions were held among 30 women and ni...

Fertility Awareness > Calendar Rhythm Method > User AttitudesFertility Awareness > Global Programs > PhilippinesResearch Methodology > Qualitative Research > Focus Groups

Preventing postoperative pelvic adhesions with intraperitoneal treatment

DeCherney AH, 1984 The Journal of Reproductive Medicine

Postoperative pelvic adhesions represent a major challenge to the surgeon operating to correct or prevent infertility. Many approaches have been tried, but intraperitoneal treatment seems to be the mo...

Surgery > Adhesion Prevention > Intraperitoneal TherapySurgery > Reproductive Surgery > Postoperative ManagementInfertility > Surgical Management > Adhesion Prevention

Effect of treatment regimens for Neisseria gonorrhoeae on simultaneous infection with Chlamydia trachomatis

Stamm WE et al., 1984 The New England Journal of Medicine

We evaluated the effect of treatment of gonorrhea on simultaneous Chlamydia trachomatis infection by randomly assigning 293 heterosexual men and 246 heterosexual women with gonorrhea to receive one of...

General OB/GYN > Sexually Transmitted Infections > Gonorrhea and Chlamydia TreatmentInfertility > Risk Factors > Sexually Transmitted InfectionsResearch Methodology > Randomized Controlled Trial > Antibiotic Comparison

High-molecular weight dextran in human infertility surgery

Rosenberg SM et al., 1984 American Journal of Obstetrics and Gynecology

The use of intraperitoneal 32% high-molecular weight dextran 70 (Hyskon, Pharmacia Inc.) has been reported to reduce the incidence of surgical adhesions in several species. The present study was under...

Surgery > Adhesion Prevention > High Molecular Weight DextranInfertility > Surgical Management > Adhesion ReductionResearch Methodology > Randomized Controlled Trial > Double-Blind Study

Cervical mucus as a biological sign of fertility and infertility

Billings JJ, 1984 Contraception, Fertilite, Sexualite

The ovulation method makes women aware of certain changes in their cervical mucus. These modifications help to distinguish the beginning and end of the cycle's fertile period and indicate the time of ...

Fertility Awareness > Cervical Mucus Monitoring > Ovulation MethodBody Literacy > Fertility Signs > Cervical Mucus PatternsFertility Awareness > Natural Family Planning > Periodic Abstinence Rules

High affinity progesterone binding sites of human uterine microsomal membranes

Haukkamaa M, 1984 Journal of Steroid Biochemistry

Microsomal membranes sedimented at 40 000 g were prepared from human myometrium samples. The progesterone binding properties of microsomal suspensions were determined by incubating microsomes and [3H]...

Reproductive Endocrinology > Progesterone > Receptor Binding MechanismsReproductive Endocrinology > Uterine Physiology > Microsomal Membrane Receptors

Correlation of maternal serum C-reactive protein with outcome of tocolysis

Handwerker SM et al., 1984 Obstetrics and Gynecology

Subclinical intrauterine infection is an important cause of preterm labor, specifically where tocolysis has failed. Fifty patients in preterm labor with singleton pregnancies were studied prospectivel...

Pregnancy > Preterm Labor > Tocolysis OutcomesPregnancy > Preterm Labor > Infection BiomarkersDiagnostics > Inflammatory Markers > C-Reactive Protein Pregnancy

High testosterone and low progesterone circulating levels in premenopausal patients with hyperplasia and cancer of the breast

Secreto G et al., 1984 Cancer Research

Serum testosterone, progesterone, luteinizing hormone, prolactin, and sex hormone-binding globulin levels were measured in 55 normal controls, in 31 patients with hyperplastic alterations of breast ep...

Reproductive Endocrinology > Progesterone > Breast Cancer RiskReproductive Endocrinology > Androgens > Testosterone and Breast DiseaseGeneral OB/GYN > Breast Health > Hormonal Risk Factors

Treatment of infertile women with a deficient postcoital test with two antiestrogens: clomiphene and tamoxifen

Roumen FJ et al., 1984 Fertility and Sterility

Twenty-two infertile women with repeated deficient results in the postcoital test received clomiphene citrate or tamoxifen. The patterns of luteinizing hormone, follicle-stimulating hormone, prolactin...

Infertility > Medical Management > Antiestrogen TherapyInfertility > Cervical Factor > Postcoital Test TreatmentReproductive Endocrinology > Ovulation Induction > Clomiphene vs Tamoxifen

Pelvic sonography to help determine the appropriate therapy for luteal phase defects

Check JH et al., 1984 International Journal of Fertility

In some series the most appropriate therapy for luteal phase defects is supplemental progesterone in the luteal phase. Clomiphene's efficacy is more controversial since in one series only 8% achieved ...

Infertility > Luteal Phase Defect > Ultrasound-Guided TherapyDiagnostics > Pelvic Ultrasound > Follicular Development AssessmentInfertility > Medical Management > Progesterone Supplementation

Oral administration of micronized natural progesterone in late human pregnancy. Effects on progesterone and estrogen concentrations in the plasma, placenta, and myometrium

Ferre F et al., 1984 American Journal of Obstetrics and Gynecology

A single dose of micronized oral progesterone was administered to 15 pregnant women immediately prior to elective cesarean section. Levels of progesterone, 17 beta-estradiol, and estrone were measured...

Reproductive Endocrinology > Progesterone > Oral Micronized PharmacokineticsPregnancy > Hormonal Physiology > Progesterone Tissue DistributionReproductive Endocrinology > Progesterone > Myometrial Concentration

The effect of progesterone administration on sex hormone binding globulin binding capacity in women with severe premenstrual syndrome

Dalton ME, 1984 Journal of Steroid Biochemistry

Thirty-one women with severe premenstrual syndrome had low sex hormone binding globulin (SHBG) binding capacities 30.2 +/- 9.4 nmol DHT bound/l. The SHBG binding capacities rose when they were treated...

Reproductive Endocrinology > Progesterone > SHBG ModulationMenstrual Cycle > Premenstrual Syndrome > Progesterone TreatmentReproductive Endocrinology > Hormonal Interactions > Progesterone and SHBG

Delayed endometrial maturation in women with normal progesterone levels. The dysharmonic luteal phase syndrome

Zorn JR et al., 1984 Gynecologic and Obstetric Investigation

In 121 women attending the infertility clinic between 1978 and 1982, 127 cycles with luteal phases of 10 days or more were investigated by a complete basal body temperature (BBT) chart, three plasma p...

Reproductive Endocrinology > Luteal Phase > Dysharmonic Luteal Phase SyndromeInfertility > Luteal Phase Defect > Endometrial Maturation DiscordanceDiagnostics > Endometrial Biopsy > Luteal Phase Assessment

Selection of morphologically abnormal sperm by human cervical mucus

Barros C et al., 1984 Archives of andrology

The important role of cervical mucus from a reproduction standpoint is the transport and selection of spermatozoa. The study of the fertilizing ability of human spermatozoa by the use of zona-free ham...

Andrology > Sperm Function > Sperm MorphologyAndrology > Sperm Function > Cervical Mucus InteractionInfertility > Cervical Factor > Sperm Selection

Uterine contractions during pregnancy

Zahn V, 1984 Journal of Perinatal Medicine

The principal function of muscular tissue is contraction. This is also true for the uterus this function begins with sexual maturation. During pregnancy special conditions are brought about by the inc...

Pregnancy > Preterm Labor > Uterine MonitoringPregnancy > Normal Physiology > Uterine ContractionsDiagnostics > Monitoring Techniques > Tocography