Intrauterine contraception with copper and with levonorgestrel: a randomized  study of the TCu 380Ag and levonorgestrel 20 mcg/day devices

Irving Sivin; Francisco Alvarez; Juan Diaz; Soledad Diaz; Sayed El Mahgoub; Elsimar Coutinho; Vivian Brache; M. Margarita Diaz; Anibal Faundes; Margarita Pavez; Carlos E. R. Mattos; Janet Stern

doi:10.1016/0010-7824(84)90036-2

Contraception · Long Acting Methods

Intrauterine contraception with copper and with levonorgestrel: a randomized study of the TCu 380Ag and levonorgestrel 20 mcg/day devices

Sivin I, Alvarez F, Diaz J, Diaz S, Mahgoub SE, Coutinho E, Brache V, Margarita Diaz M, Faundes A, Pavez M, Mattos CER, Stern J

Published November 1984 Contraception, 30(5), 443-456

DOI 10.1016/0010-7824(84)90036-2 PMID 6440740

Abstract

First year results of a randomized study of 1509 users of the Copper T380Ag with a silver core or of an IUD releasing 20 mcg day of levonorgestrel are reported. The cumulative gross pregnancy rate for each device was 0.3 per 100 at one year, with more than 490 women having one year of use with each device. The levonorgestrel-releasing device was associated with significantly fewer bleeding days and significantly increased hemoglobin levels when compared with pre-admission values or the one year values observed among users of the TCu380Ag. Terminations attributable to amenorrhea were significantly more frequent among users of the levonorgestrel-releasing device. The TCu 380Ag was associated with increased frequency and severity of dysmenorrhea compared with pre-admission levels or with the steroid-releasing device. Hemoglobin levels were somewhat reduced among users of the TCu 380Ag device. Terminations attributable to pain were, however, not significantly different by device. Continuation rates at the end of the first year were not significantly different by device.

Topics

Contraception Long Acting Methods Intrauterine Devices

Contraception › Long Acting Methods › Intrauterine Devices

Irving Sivin, Francisco Alvarez, Juan Diaz, Soledad Diaz, Sayed El Mahgoub, Elsimar Coutinho, Vivian Brache, M. Margarita Diaz, Anibal Faundes, Margarita Pavez, Carlos E. R. Mattos, Janet Stern

I Sivin, F Alvarez, J Diaz, S Diaz, S Mahgoub, E Coutinho, V Brache, A Faundes, M Pavez, C Mattos, J Stern

PMID 6440740 6440740 DOI 10.1016/0010-7824(84)90036-2 10.1016/0010-7824(84)90036-2 Sivin et al. 1984, Sivin 1984

Keywords

Contraceptives, Oral, Combined, Norgestrel, Levonorgestrel

Intrauterine contraception with copper and with levonorgestrel: a randomized study of the TCu 380Ag and levonorgestrel 20 mcg/day devices

Abstract

Topics

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