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Ovarian cancer and infertility: a genetic link?

Nieto JJ et al. 1999 Lancet (London, England)

A genetic mechanism may be responsible for the increased incidence of ovarian cancer in some infertile women (ie, those who failed to conceive despite treatment).

Ovarian Cancer RiskOvarian Cancer Genetics

Amniotic fluid concentrations of interleukin-1beta, interleukin-6 and TNF-alpha in chorioamnionitis before 32 weeks of gestation: histological associations and neonatal outcome

Baud O et al. 1999 British Journal of Obstetrics and Gynaecology

OBJECTIVES: To test the association between cytokine levels in the amniotic fluid and (i) the vascular invasion phase of intrauterine infection, (ii) the occurrence of periventricular leukomalacia; to...

ChorioamnionitisCytokine MarkersInflammatory Cytokines

[Polycystic ovary syndrome--only relevant in reproductive medicine?]

Heim SC et al. 1999 Therapeutische Umschau. Revue Therapeutique

The Polycystic Ovary Disease (PCOD) is one of the most common endocrine disorders in women with a prevalence of 5%. Affected women often consult a gynecologist because of menstrual irregularities, fer...

Cardiovascular RiskInterdisciplinary ApproachLong-term Health Outcomes

Adjuvant L-arginine treatment for in-vitro fertilization in poor responder patients

Battaglia C et al. 1999 Human Reproduction (Oxford, England)

The objective of the present study was prospectively and randomly to evaluate the role of L-arginine in improving uterine and follicular Doppler flow and in improving ovarian response to gonadotrophin...

L-Arginine SupplementationTreatment StrategiesUterine and Follicular Blood Flow

Change in cervical length after prophylactic cerclage

Funai EF et al. 1999 Open Access Obstetrics and Gynecology

OBJECTIVE: To determine changes in length of incompetent cervices after cerclage, using transvaginal ultrasound. METHODS: Patients were enrolled in a prospective, observational study under an Institu...

CerclagePreventionCervical Length Measurement

Running and ovulation positively change cancellous bone in premenopausal women

Petit MA et al. 1999 Medicine and Science in Sports and Exercise

Purpose: Exercise is understood to exert positive effects on bone. However cancellous bone has not been shown to increase with exercise. Previous results of our 1-yr observational prospective study in...

Exercise and Ovulation EffectsBone Density ImpactSkeletal Health

Amniotic fluid concentrations of adrenomedullin in preterm labor

Marinoni E et al. 1999 Obstetrics and Gynecology

OBJECTIVE: To determine whether adrenomedullin levels in amniotic fluid were associated with preterm labor. METHODS: We measured immunoreactive adrenomedullin in amniotic fluid collected by amniocent...

BiomarkersPremature Rupture of MembranesPeptide Markers

The differential risk of oral contraceptives: the impact of full exposure history

Lewis MA et al. 1999 Human Reproduction (Oxford, England)

Previous discussions have indicated that the small increases of risk of venous thromboembolism (VTE) associated with newer combined oral contraceptives (third generation, containing desogestrel and ge...

Venous Thromboembolism RiskThird vs Second Generation PillsBias Adjustment

The epidemiology of polycystic ovary syndrome. Prevalence and associated disease risks

Solomon CG 1999 Endocrinology and Metabolism Clinics of North America

Polycystic ovary syndrome is a common problem affecting approximately 5% of women of reproductive age when defined by clinical features of anovulation and hyperandrogenism. Metabolic derangements asso...

Prevalence and Disease AssociationsMetabolic and Cardiovascular RiskLifestyle and Pharmacological Approaches

Uses of progesterone in clinical practice

Warren MP et al. 1999 International Journal of Fertility and Women's Medicine

Progesterone is the natural progestagen produced by the corpus luteum during the luteal phase. It is absorbed when administered orally, but is greater than 90% metabolized during the first hepatic pas...

Routes of AdministrationClinical ApplicationsVaginal Progesterone

Pathophysiology and management of proximal tubal blockage

Honoré GM et al. 1999 Fertility and Sterility

OBJECTIVE: To review the physiology, pathology, and treatment of proximal tubal disease. DATA IDENTIFICATION: Relevant reports on the pathophysiology of proximal tubal disease were reviewed. All stud...

Proximal Tubal ObstructionTubal CannulationSurgical Outcomes

Oral-contraceptive use and risk of hip fracture: a case-control study

Michaëlsson K et al. 1999 Lancet

Background: Epidemiological studies indicate a protective effect of postmenopausal oestrogen therapy on the risk of osteoporotic fractures. Whether premenopausal oestrogen exposure in the form of oral...

Bone EffectsOral Contraceptive AssociationPopulation-Based

Pitfalls in ultrasonic cervical length measurement for predicting preterm birth

Yost NP et al. 1999 Obstetrics and Gynecology

OBJECTIVE: To describe the anatomic and technical difficulties encountered with transvaginal ultrasound imaging of the cervix in a consecutive series of women at risk for preterm delivery. METHODS: T...

Cervical Length AssessmentCervical Imaging PitfallsPreterm Delivery Prediction

Endometriosis: a clinically malignant disease

Henkel A et al. 1999 European Journal of Obstetrics, Gynecology, and Reproductive Biology

According to the literature this is the first patient with the primary diagnosis of an endometriosis (EMT) based on the cardinal symptom of an uremia in combination with a colorectal ileus. Operative ...

Organ InvolvementHormonal SuppressionDeep Infiltrating Disease

Human assisted conception: a cautionary tale. Lessons from domestic animals

Leese HJ et al. 1999 Human Reproduction (Oxford, England)

A variety of embryo-based technologies used in farm animal reproduction, including embryo culture, nuclear transfer, embryo-somatic cell co-culture and asynchronous embryo transfer can lead to the pro...

Safety Concerns and RisksPrecautionary PrinciplesEmbryo Development

The prevalence of polycystic ovaries in healthy women

Koivunen R et al. 1999 Acta Obstetricia Et Gynecologica Scandinavica

BACKGROUND: To study the prevalence of polycystic ovaries (PCO) in women of reproductive age. METHODS: A total of 189 healthy volunteers aged 20-45 years were examined. The subjects were divided into...

Ultrasound CriteriaPrevalence StudiesTransvaginal Ultrasound

Relationship between endometriosis and ovarian cancer

Erzen M et al. 1999 European Journal of Gynaecological Oncology

PURPOSE: To investigate the occurrence of ovarian cancer (OC) arising in ovarian endometriosis (OE) diagnosed in our laboratory, and the relation of the disease to patient age. METHODS: Histopatholog...

Malignant TransformationOvarian CancerOvarian Endometriosis

Cesarean section scar as a cause of abnormal vaginal bleeding: diagnosis by sonohysterography

Thurmond AS et al. 1999 Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine

A previously undescribed cause of abnormal uterine bleeding is presented. Nine of 310 women evaluated by sonohysterography for abnormal bleeding demonstrated an 8 to 17 mm gap in the anterior lower ut...

Cesarean Scar DefectSonohysterographyPostmenstrual Spotting

Effect of opioid blockade on insulin and growth hormone (GH) secretion in patients with polycystic ovary syndrome: the heterogeneity of impaired GH secretion is related to both obesity and hyperinsulinism

Villa P et al. 1999 Fertility and Sterility

OBJECTIVE: To investigate the involvement of opioid tone, obesity, and hyperinsulinemia in GH secretion in women with polycystic ovary syndrome (PCOS). DESIGN: Controlled clinical study. SETTING: Ca...

Growth Hormone SecretionOpioid AntagonistsPCOS Hyperinsulinemia

Grief, depression, and coping in women undergoing infertility treatment

Lukse MP et al. 1999 Obstetrics and Gynecology

OBJECTIVE: To identify the levels of grief and depression and the coping mechanisms of women with infertility problems who participated in in vitro fertilization (IVF) or ovulation-induction medicatio...

Grief and DepressionCounseling InterventionsCoping Strategies

Female infertility

Hull MG et al. 1999 Endocrinology and Metabolism Clinics of North America

This article has provided outcome-based evidence using easily understood graphic representation of cumulative pregnancy rates whenever possible for the methods used to investigate and treat female inf...

Diagnostic InvestigationEvidence-Based OutcomesInfertility Management

Ovarian cancer in infertility patients

Burmeister L et al. 1999 Annals of Medicine

The possibility that ovulation induction increases the risk of ovarian cancer remains unproven. However, recent studies suggest that both infertility and endometriosis may be independent risk factors....

Ovarian CancerOvarian Cancer Risk FactorsCancer Risk

The influence of oral contraceptives on the risk of multiple sclerosis

Thorogood M et al. 1999 British Journal of Obstetrics and Gynaecology

Objective: To examine the risk of multiple sclerosis in users of combined oral contraceptives. Design: Cohort study conducted between 1968 and 1996 using diagnostic data supplied by general practition...

Neurological DiseaseAutoimmune RiskProspective Cohort