The Journal of Reproductive Medicine, 44(2 Suppl), 141-147, 2001
Pharmacokinetics of progesterone administered by the oral and parenteral routes
Author affiliations
- University of Southern California ROR
Abstract
Progestogens, which include the natural hormone, progesterone, and synthetic steroid derivatives, are used to treat a variety of reproductive disorders. Since synthetic progestogens are often associated with undesirable side effects, improved formulations and modes of administration of progesterone have been sought. In order to find an optimal therapeutic agent, different progesterone formulations and routes of administration have been studied. This paper explains several methods of measuring progesterone levels and summarizes clinical data on the pharmacokinetic profiles of natural progesterone administered by the oral, intramuscular, vaginal, intranasal, percutaneous, sublingual and rectal routes.
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Cite this article
Stanczyk, F. Z. (1999). Pharmacokinetics of progesterone administered by the oral and parenteral routes. *The Journal of reproductive medicine*, *44*(2 Suppl), 141-147.
Stanczyk FZ. Pharmacokinetics of progesterone administered by the oral and parenteral routes. J Reprod Med. 1999;44(2 Suppl):141-147.
Stanczyk, Frank Z. "Pharmacokinetics of progesterone administered by the oral and parenteral routes." *The Journal of reproductive medicine*, vol. 44, no. 2 Suppl, 1999, pp. 141-147.
Keywords
Administration, Oral, Biological Assay, Chemistry, Pharmaceutical, Drug Administration Routes, Female, Humans, Progesterone/administration & Dosage/analysis/pharmacokinetics, Progesterone