Boostanfar, R., Jain, J. K., Mishell, D. R., Jr., & Paulson, R. J. (2001). A prospective randomized trial comparing clomiphene citrate with tamoxifen citrate for ovulation induction. Fertility and Sterility, 75(5), 1024-1026. https://doi.org/10.1016/s0015-0282(01)01749-6
Boostanfar R, Jain JK, Mishell DR Jr, Paulson RJ. A prospective randomized trial comparing clomiphene citrate with tamoxifen citrate for ovulation induction. Fertil Steril. 2001;75(5):1024-1026. doi:10.1016/s0015-0282(01)01749-6
Boostanfar, Robert, et al. "A prospective randomized trial comparing clomiphene citrate with tamoxifen citrate for ovulation induction." Fertility and Sterility, vol. 75, no. 5, 2001, pp. 1024-1026.
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To compare the rates of ovulation and pregnancy after tamoxifen citrate (TMX) or clomiphene citrate (CC) among anovulatory women with infertility.
Design
Prospective randomized trial.
Setting
Infertility clinic in a university teaching hospital.
Patients
Eighty-six anovulatory women under 40 years of age undergoing ovulation induction.
Interventions
The women were assigned randomly to receive either TMX or CC on cycle days 5-9.
Main Outcome Measures
Rates of ovulation and pregnancy for the two treatment modalities.
Results
The overall rate of ovulation in the TMX group was 50 of 113 (44.2%) and in the CC group, 41 of 91 (45.1%). There were 10 pregnancies in the TMX group and 6 pregnancies in the CC group. The cycle fecundity per ovulatory cycle was 20.0% in the TMX group and 14.6% in the CC group.
Conclusions
The overall rate of ovulation and pregnancy were similar with TMX and CC. TMX is a suitable alternative agent to CC in the management of anovulatory infertility.
Robert Boostanfar, John K Jain, Daniel R Mishell Jr, Richard J Paulson
Bob Boostanfar, Rob Boostanfar, Bobby Boostanfar, R Boostanfar, Jack Jain, J Jain, Dan Mishell, Danny Mishell, D Mishell, Rick Paulson, Dick Paulson, Rich Paulson, R Paulson
PMID 11334921 11334921 DOI 10.1016/s0015-0282(01)01749-6 10.1016/s0015-0282(01)01749-6 Boostanfar et al. 2001, Boostanfar 2001
