Physiologic effects of lowering caloric intake in nonhuman primates and nonobese humans

Roberts SB; Pi-Sunyer X; Kuller L; Lane MA; Ellison P; Prior JC; Shapses S

doi:10.1093/gerona/56.suppl_1.66

Lifestyle and Environment Nutrition and Metabolic Health

Physiologic effects of lowering caloric intake in nonhuman primates and nonobese humans

Roberts SB, Pi-Sunyer X, Kuller L, Lane MA, Ellison P, Prior JC, Shapses S

Published March 2001 J Gerontol A Biol Sci Med Sci, 56 Spec No 1(Supplement 1), 66-75

DOI 10.1093/gerona/56.suppl_1.66 PMID 12088214

Abstract

Caloric restriction (CR) reduces the rate of aging and increases life span in all small animal species studied to date, but the effects of CR in humans remain uncertain. This review summarizes current knowledge of the effects of CR in nonhuman primates and humans. The results suggest that CR has a range of beneficial effects in nonhuman primates studied under laboratory conditions, and short-term markers of CR seen in animal models appear to occur in humans subject to CR also. However, the overall benefit of CR in human populations remains to be established, and studies in human populations are needed.

Topics

Lifestyle and Environment

Nutrition and Metabolic Health Dietary Patterns

Lifestyle and Environment › Nutrition and Metabolic Health › Dietary Patterns

Lewis H Kuller, Mark A Lane, Jerilynn C Prior

L Kuller, M Lane, J Prior

PMID 12088214 12088214 DOI 10.1093/gerona/56.suppl_1.66 10.1093/gerona/56.suppl_1.66 Roberts et al. 2001, Roberts 2001

Physiologic effects of lowering caloric intake in nonhuman primates and nonobese humans

Abstract

Topics

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