General Gynecology · Breast Health

Estrogen carcinogenesis in breast cancer

Yager JD, Davidson NE

Published January 19, 2006 The New England Journal of Medicine, 354(3), 270-282
DOI 10.1056/NEJMra050776 PMID 16421368

Abstract

Estrogen exposure is a major determinant of the risk of breast cancer. This article reviews how genotoxic, mutagenic metabolites of estrogen and stimulation of tissue growth by the hormone participate in the pathogenesis of breast cancer.

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General Gynecology › Breast Health › Breast Cancer Risk
James D Yager, Nancy E Davidson
Jim Yager, Jimmy Yager, J Yager, N Davidson
PMID 16421368 16421368 DOI 10.1056/NEJMra050776 10.1056/NEJMra050776 Yager et al. 2006, Yager 2006