A genetic mechanism may be responsible for the increased incidence of ovarian cancer in some infertile women (ie, those who failed to conceive despite treatment).
Infertility > Complications > Ovarian Cancer RiskGeneral OB/GYN > Gynecologic Oncology > Ovarian Cancer Genetics
OBJECTIVE: To describe a computerized pelvic mapping system for pelvic and intestinal endometriosis and preliminary insights gained from it with respect to the effects of ovarian disease.
DESIGN: Con...
OBJECTIVE: To determine effectiveness of transdermal progesterone cream for controlling vasomotor symptoms and preventing postmenopausal bone loss.
METHODS: We randomly assigned 102 healthy women wit...
Perimenopause/Menopause > Vasomotor Symptoms > Progesterone TreatmentBone Health > Postmenopausal Bone Loss > Progesterone TherapyPerimenopause/Menopause > Hormone Therapy > Transdermal Progesterone
OBJECTIVE: To compare the effectiveness of finasteride and flutamide in the treatment of idiopathic hirsutism.
DESIGN: Randomized study.
SETTING: Department of Gynecological Endocrinology, Universit...
OBJECTIVE: To assess the intratubal pressure (ITP) and patency status of the fallopian tubes before and after transcervical catheterization of the fallopian tubes (TCFT).
DESIGN: Prospective procedur...
Surgery > Tubal Surgery > Transcervical CatheterizationNaProTECHNOLOGY > Surgical Interventions > Tubal AssessmentInfertility > Tubal Factor > Proximal Tubal Obstruction
DESIGN OF THE PROJECT: This study is the result of a detailed examination of numerous historical documents as well as several contemporary works describing endometriosis. The historic texts are housed...
Endometriosis > History > Historical DescriptionsResearch Methodology > Historical Analysis > Medical History
Baud O et al., 1999British Journal of Obstetrics and Gynaecology
OBJECTIVES: To test the association between cytokine levels in the amniotic fluid and (i) the vascular invasion phase of intrauterine infection, (ii) the occurrence of periventricular leukomalacia; to...
Heim SC et al., 1999Therapeutische Umschau. Revue Therapeutique
The Polycystic Ovary Disease (PCOD) is one of the most common endocrine disorders in women with a prevalence of 5%. Affected women often consult a gynecologist because of menstrual irregularities, fer...
Battaglia C et al., 1999Human Reproduction (Oxford, England)
The objective of the present study was prospectively and randomly to evaluate the role of L-arginine in improving uterine and follicular Doppler flow and in improving ovarian response to gonadotrophin...
Locksmith GJ et al., 1999Obstetrics and Gynecology
OBJECTIVE: To determine the accuracy of amniotic fluid (AF) matrix metalloproteinase-9 measurements for diagnosing intra-amniotic infection in women with preterm labor.
METHODS: We performed amniocen...
Funai EF et al., 1999
Open Access
Obstetrics and Gynecology
OBJECTIVE: To determine changes in length of incompetent cervices after cerclage, using transvaginal ultrasound.
METHODS: Patients were enrolled in a prospective, observational study under an Institu...
Petit MA et al., 1999Medicine and Science in Sports and Exercise
Purpose: Exercise is understood to exert positive effects on bone. However cancellous bone has not been shown to increase with exercise. Previous results of our 1-yr observational prospective study in...
Bone Health > Premenopausal > Exercise and Ovulation EffectsMenstrual Cycle > Luteal Phase > Bone Density ImpactReproductive Endocrinology > Ovulatory Function > Skeletal Health
OBJECTIVE: To determine whether adrenomedullin levels in amniotic fluid were associated with preterm labor.
METHODS: We measured immunoreactive adrenomedullin in amniotic fluid collected by amniocent...
Lewis MA et al., 1999Human Reproduction (Oxford, England)
Previous discussions have indicated that the small increases of risk of venous thromboembolism (VTE) associated with newer combined oral contraceptives (third generation, containing desogestrel and ge...
Contraception/Comparison > Oral Contraceptives > Venous Thromboembolism RiskContraception/Comparison > Safety > Third vs Second Generation PillsResearch Methodology > Case-Control Studies > Bias Adjustment
Todd J et al., 1999Human Reproduction (Oxford, England)
In October 1995 the Committee on Safety of Medicines advised UK doctors and pharmacists that oral contraceptives containing desogestrel and gestodene were associated with double the risk of venous thr...
Solomon CG, 1999Endocrinology and Metabolism Clinics of North America
Polycystic ovary syndrome is a common problem affecting approximately 5% of women of reproductive age when defined by clinical features of anovulation and hyperandrogenism. Metabolic derangements asso...
PCOS > Epidemiology > Prevalence and Disease AssociationsPCOS > Comorbidities > Metabolic and Cardiovascular RiskPCOS > Management > Lifestyle and Pharmacological Approaches
Warren MP et al., 1999International Journal of Fertility and Women's Medicine
Progesterone is the natural progestagen produced by the corpus luteum during the luteal phase. It is absorbed when administered orally, but is greater than 90% metabolized during the first hepatic pas...
Camus E et al., 1999Human Reproduction (Oxford, England)
This meta-analysis was intended to evaluate differences in pregnancy rates after in-vitro fertilization (IVF) in tubal fertility with and without hydrosalpinx. It examined nine published retrospective...
Infertility > Tubal Factor > Hydrosalpinx Impact on IVFInfertility > ART Outcomes > Pregnancy and Implantation RatesResearch Methodology > Meta-Analysis > Reproductive Outcomes
Wiseman DM et al., 1999The Journal of Reproductive Medicine
OBJECTIVE: To evaluate the safety and efficacy of an oxidized, regenerated, cellulose adhesion barrier (Interceed TC7) in the reduction of pelvic adhesions.
STUDY DESIGN: Clinical studies published o...
Surgery > Adhesion Prevention > Barrier MethodsSurgery > Pelvic Surgery > Laparotomy OutcomesResearch Methodology > Meta-Analysis > Surgical Interventions
OBJECTIVE: To review the physiology, pathology, and treatment of proximal tubal disease.
DATA IDENTIFICATION: Relevant reports on the pathophysiology of proximal tubal disease were reviewed. All stud...
Surgery > Tubal Surgery > Proximal Tubal ObstructionInfertility > Tubal Factor > Tubal CannulationResearch Methodology > Meta-Analysis > Surgical Outcomes
OBJECTIVE: To investigate a possible linkage between the use of fertility drugs for infertility and the risk of breast and ovarian cancers.
DESIGN: Long-term, historic-prospective study.
SETTING: Fe...
Infertility > Treatment Risks > Cancer Risk from Fertility DrugsGeneral OB/GYN > Oncology > Breast Cancer Risk FactorsResearch Methodology > Cohort Studies > Long-term Follow-up
Background: Epidemiological studies indicate a protective effect of postmenopausal oestrogen therapy on the risk of osteoporotic fractures. Whether premenopausal oestrogen exposure in the form of oral...
Contraception/Comparison > Health Outcomes > Bone EffectsBone Health > Fracture Risk > Oral Contraceptive AssociationResearch Methodology > Case-Control Studies > Population-Based
Nestler JE et al., 1999The New England Journal of Medicine
BACKGROUND: Women with the polycystic ovary syndrome have insulin resistance and hyperinsulinemia, possibly because of a deficiency of a D-chiro-inositol-containing phosphoglycan that mediates the act...
OBJECTIVE: To describe the anatomic and technical difficulties encountered with transvaginal ultrasound imaging of the cervix in a consecutive series of women at risk for preterm delivery.
METHODS: T...
Henkel A et al., 1999European Journal of Obstetrics, Gynecology, and Reproductive Biology
According to the literature this is the first patient with the primary diagnosis of an endometriosis (EMT) based on the cardinal symptom of an uremia in combination with a colorectal ileus. Operative ...
Endometriosis > Complications > Organ InvolvementEndometriosis > Treatment > Hormonal SuppressionSurgery > Endometriosis Surgery > Deep Infiltrating Disease
OBJECTIVE: To evaluate the efficacy of oral micronized progesterone compared with IM progesterone in oil for luteal support in patients undergoing IVF who are treated with a GnRH agonist.
DESIGN: Ran...
OBJECTIVE: To investigate whether the timing of administration of clomiphene citrate (CC) affects hormone levels, follicular recruitment, reproductive end organs, and pregnancy rates.
DESIGN: Prospec...
Leese HJ et al., 1999Human Reproduction (Oxford, England)
A variety of embryo-based technologies used in farm animal reproduction, including embryo culture, nuclear transfer, embryo-somatic cell co-culture and asynchronous embryo transfer can lead to the pro...
OBJECTIVE: To characterize how the menstrual cycle pattern relates to fertility regardless of potential biases caused by inappropriate coital timing during the menstrual cycle or early embryonal loss....
OBJECTIVE: To determine whether IVF or a standard infertility treatment algorithm results in better outcome and/or lower cost when used as first-line therapy for couples with infertility.
DESIGN: Pro...
Papiernik E et al., 1999Journal of Perinatal Medicine
This article reviews the arguments for the use of multifetal pregnancy reduction (MFPR) for the prevention of preterm deliveries in triplet and higher order multiple pregnancies and evaluates its effe...
Zhang F et al., 1999Chemical Research in Toxicology
The risk factors for women developing breast and endometrial cancers are all associated with a lifetime of estrogen exposure. Estrogen replacement therapy in particular has been correlated with a slig...
Koivunen R et al., 1999Acta Obstetricia Et Gynecologica Scandinavica
BACKGROUND: To study the prevalence of polycystic ovaries (PCO) in women of reproductive age.
METHODS: A total of 189 healthy volunteers aged 20-45 years were examined. The subjects were divided into...
Althuisius SM et al., 1999American Journal of Obstetrics and Gynecology
OBJECTIVE: Our goal was to study the effect of therapeutic McDonald cerclage on cervical length with the use of transvaginal ultrasonography.
STUDY DESIGN: Cervical length was measured serially in si...
OBJECTIVE: To determine the prevalence of polycystic ovary syndrome (PCOS) among hyperandrogenic women who report normal menses.
DESIGN: Prospective observational study.
SETTING: Academic practice i...
Erzen M et al., 1999European Journal of Gynaecological Oncology
PURPOSE: To investigate the occurrence of ovarian cancer (OC) arising in ovarian endometriosis (OE) diagnosed in our laboratory, and the relation of the disease to patient age.
METHODS: Histopatholog...
Thurmond AS et al., 1999Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine
A previously undescribed cause of abnormal uterine bleeding is presented. Nine of 310 women evaluated by sonohysterography for abnormal bleeding demonstrated an 8 to 17 mm gap in the anterior lower ut...
There is a growing threat to the practice of oocyte donation in the United States and all of us should take careful notice. This threat is posed by the escalating fees paid to young women for providin...
OBJECTIVE: To investigate the involvement of opioid tone, obesity, and hyperinsulinemia in GH secretion in women with polycystic ovary syndrome (PCOS).
DESIGN: Controlled clinical study.
SETTING: Ca...
OBJECTIVE: To identify the levels of grief and depression and the coping mechanisms of women with infertility problems who participated in in vitro fertilization (IVF) or ovulation-induction medicatio...
Infertility > Psychological Impact > Grief and DepressionInfertility > Patient Support > Counseling InterventionsGeneral OB/GYN > Mental Health > Coping Strategies
Hull MG et al., 1999Endocrinology and Metabolism Clinics of North America
This article has provided outcome-based evidence using easily understood graphic representation of cumulative pregnancy rates whenever possible for the methods used to investigate and treat female inf...
The possibility that ovulation induction increases the risk of ovarian cancer remains unproven. However, recent studies suggest that both infertility and endometriosis may be independent risk factors....
Infertility > Risks of Treatment > Ovarian CancerGeneral OB/GYN > Oncology > Ovarian Cancer Risk FactorsEndometriosis > Complications > Cancer Risk
OBJECTIVE: To evaluate and compare the safety and efficacy of leuprolide versus placebo in managing chronic pelvic pain in women with clinically suspected endometriosis.
METHODS: Women 18-45 years of...
Bloemenkamp KW et al., 1999Archives of Internal Medicine
Background: The magnitude of the relative risk of venous thrombosis caused by low-dose oral contraceptive use is still debated because previous studies might have been affected by diagnostic suspicion...
Thorogood M et al., 1999British Journal of Obstetrics and Gynaecology
Objective: To examine the risk of multiple sclerosis in users of combined oral contraceptives.
Design: Cohort study conducted between 1968 and 1996 using diagnostic data supplied by general practition...