Studies on pituitary and ovarian function as assessed by the urinary output of total gonadotrophic activity, the three classical oestrogens, pregnanediol and, in some cases, testosterone and epitestosterone, were conducted in eight patients suffering from premenstrual tension. Major abnormalities in endocrine function were not a feature of the condition. Ovulation, as judged by pregnanediol assays, was absent in seven out of the fifteen cycles investigated. Contrary to traditional belief, the symptoms of premenstrual tension could exist in the presence of cycles with anovulatory hormonal patterns.
PMID 4677133 4677133 DOI 10.1111/j.1365-2265.1972.tb00400.x 10.1111/j.1365-2265.1972.tb00400.x
Cite this article
Adamopoulos, D. A., Loraine, J. A., Lunn, S. F., Coppen, A. J., & Daly, R. J. (1972). Endocrine profiles in premenstrual tension. *Clinical endocrinology*, *1*(3), 283-292. https://doi.org/10.1111/j.1365-2265.1972.tb00400.x
Adamopoulos DA, Loraine JA, Lunn SF, Coppen AJ, Daly RJ. Endocrine profiles in premenstrual tension. Clin Endocrinol (Oxf). 1972;1(3):283-292. doi:10.1111/j.1365-2265.1972.tb00400.x
Adamopoulos, D. A., et al. "Endocrine profiles in premenstrual tension." *Clinical endocrinology*, vol. 1, no. 3, 1972, pp. 283-292.
OBJECTIVES: Functional hypothalamic amenorrhoea (FHA) is a common cause of amenorrhoea, but diagnosis can be challenging. The aim of this study was to investigate the clinical and biochemical features...
Goshtasebi A et al., 2019
Open Access
Clinical Endocrinology
Objective: Many women use combined hormonal contraceptives (CHC) during adolescence during which they are accruing peak areal bone mineral density (BMD) that relates to lifetime fracture risk. To buil...
Bone Health > Contraception Impact > Adolescent Peak BMD AccrualContraception/Comparison > Combined Hormonal > Bone Health EffectsResearch Methodology > Meta-Analysis > Prospective Controlled Studies
CONTEXT: Weight loss remains one of the most important arms in obese patients with polycystic ovary syndrome (PCOS). Further studies are needed to identify the best treatment.
OBJECTIVE: To evaluate ...
OBJECTIVE: To our knowledge, data on comparison of myo-inositol and metformin on clinical, metabolic and genetic parameters in subjects with polycystic ovary syndrome (PCOS) are limited. This study wa...