Antonio Malvasi, Giuseppe Trojano, Cecilia Angelucci
Domenico Baldini, Giorgio Maria Baldini, Doriana Di Nanni , Antonio Simone Laganà, Dario Lot , Andrea Tinelli
Author affiliations (7)
Obstetrics and Gynecology Unit, Department of Biomedical Sciences and Human Oncology, University of Bari “Aldo Moro”, Piazza Giulio Cesare 11, 70124 Bari, Italy
Isthmocele is a gynecological condition characterized by a disruption in the uterine scar, often associated with prior cesarean sections. This anatomical anomaly can be attributed to inadequate or insufficient healing of the uterine wall following a cesarean incision. It appears that isthmocele may impact a woman's quality of life as well as her reproductive capacity. The incidence of isthmocele can range from 20% to 70% in women who have undergone a cesarean section. This review aims to sum up the current knowledge about the effect of isthmocele on fertility and the possible therapeutic strategies to achieve pregnancy. However, currently, there is not sufficiently robust evidence to indicate the need for surgical correction in all asymptomatic patients seeking fertility. In cases where surgical correction of isthmocele is deemed necessary, it is advisable to evaluate residual myometrial thickness (RMT). For patients with RMT >2.5-3 mm, hysteroscopy appears to be the technique of choice. In cases where the residual tissue is lower, recourse to laparotomic, laparoscopic, or vaginal approaches is warranted.
PMID 38673465 38673465 DOI 10.3390/jcm13082192 10.3390/jcm13082192
Cite this article
Baldini, G. M., Lot, D., Malvasi, A., Di Nanni, D., Laganà, A. S., Angelucci, C., Tinelli, A., Baldini, D., & Trojano, G. (2024). Isthmocele and Infertility. Journal of clinical medicine, 13(8), 2192. https://doi.org/10.3390/jcm13082192
Baldini GM, Lot D, Malvasi A, Di Nanni D, Laganà AS, Angelucci C, et al. Isthmocele and Infertility. J Clin Med. 2024;13(8):2192. doi:10.3390/jcm13082192
Baldini, G. M., et al. "Isthmocele and Infertility." Journal of clinical medicine, vol. 13, no. 8, 2024, pp. 2192.
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