Light exposure of the ovum and preimplantation embryo during ART procedures

Lars D M Ottosen; Johnny Hindkjaer; Jakob Ingerslev

doi:10.1007/s10815-006-9081-x

Lifestyle and Environment · Environmental Exposures

Light exposure of the ovum and preimplantation embryo during ART procedures

Ottosen LD, Hindkjaer J, Ingerslev J

Journal of assisted reproduction and genetics, 24(2-3), 99-103, 2007

DOI 10.1007/s10815-006-9081-x PMID 17216346 PMC PMC3454986

Abstract

Exposure to visible light (400-700 nm wavelengths) is an unnatural stress factor to preimplantation embryos cultured in vitro. This study investigated the spectral composition and intensity of light during IVF procedures, and calculated radiation doses reaching the embryo during handling and manipulation. The study shows that normal IVF procedure may result in stressing radiation doses, unless filters are applied. This is at present not sufficiently recognised. No Danish IVF clinics use filters to protect embryos against visible light. 95% of the radiation was from microscopes. Ambient light, in contrast, was not a significant contributor to light stress and the use of dark laboratories is not justified.

Topics

Lifestyle and Environment › Environmental Exposures › Radiation and Electromagnetic Exposure · Assisted Reproduction › Safety and Risks › Procedural Safety

Lars D M Ottosen, Johnny Hindkjaer, Jakob Ingerslev

L Ottosen, J Hindkjaer, J Ingerslev

PMID 17216346 17216346 DOI 10.1007/s10815-006-9081-x 10.1007/s10815-006-9081-x Ottosen et al. 2007, Ottosen 2007

Light exposure of the ovum and preimplantation embryo during ART procedures

Abstract

Topics

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