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A randomised controlled trial of vaginal clindamycin for early pregnancy bacterial vaginosis

Kurkinen-Raty M et al., 2000 BJOG : an international journal of obstetrics and gynaecology

Objective: To assess maternal morbidity, and neonatal outcome and especially long term sequelae in infants born preterm due to maternal or fetal indications. Design: Analysis of retrospective cohort. ...

Pregnancy > Preterm Birth > Indicated vs Spontaneous Delivery OutcomesPregnancy > Neonatal Outcomes > Respiratory MorbidityGeneral OB/GYN > Cesarean Delivery > Preterm Indications

Obstetric outcome of pregnancies following ICSI, classified according to sperm origin and quality

Wennerholm UB et al., 2000 Human Reproduction (Oxford, England)

The aim of this study was to report the outcome of all clinical pregnancies obtained after intracytoplasmic sperm injection (ICSI) performed during a 5 year period at two fertility clinics, with speci...

Infertility > ART Outcomes > ICSI Pregnancy OutcomesPregnancy > Multiple Pregnancy > ART-Related ComplicationsAndrology > Sperm Quality > ICSI Outcomes by Sperm Source

Comparison between different routes of progesterone administration as luteal phase support in infertility treatments

Tavaniotou A et al., 2000 Human Reproduction Update

Different routes of natural progesterone supplementation have been tried as luteal phase support in infertility treatments. Orally administered progesterone is rapidly metabolized in the gastrointesti...

Reproductive Endocrinology > Progesterone Therapy > Luteal Phase SupportInfertility > ART Protocols > Progesterone Administration RoutesReproductive Endocrinology > Endometrial Development > Secretory Transformation

Nausea and vomiting during pregnancy: A prospective study of its frequency, intensity, and patterns of change

Lacroix R et al., 2000 American Journal of Obstetrics and Gynecology

OBJECTIVE: Our purpose was to provide a detailed description of patterns of nausea and vomiting of pregnancy. STUDY DESIGN: A prospective study was performed with 160 women who provided daily recordi...

Pregnancy > Nausea and Vomiting > Epidemiology and PatternsPregnancy > Maternal Symptoms > Symptom Assessment ToolsResearch Methodology > Prospective Studies > Symptom Tracking

Evaluation of four automated high-sensitivity C-reactive protein methods: implications for clinical and epidemiological applications

Roberts WL et al., 2000 Clinical Chemistry

BACKGROUND: C-reactive protein (CRP) can provide prognostic information about the risk of developing atherosclerotic complications in apparently healthy patients. This new clinical application require...

Diagnostics > Inflammatory Markers > High-Sensitivity CRP MethodsResearch Methodology > Laboratory Methods > Assay Comparison and Standardization

Indomethacin for preterm labor: a randomized comparison of vaginal and rectal-oral routes

Abramov Y et al., 2000 Obstetrics and Gynecology

OBJECTIVE: To compare the efficacy of intravaginal and intrarectal plus oral indomethacin for the treatment of preterm labor. METHODS: Between December 1996 and November 1998, 46 eligible gravidas ad...

Pregnancy > Preterm Birth > Tocolytic TherapyPregnancy > Preterm Labor > Drug Administration RoutesResearch Methodology > Randomized Controlled Trials > Tocolysis Comparison

Neonatal effects of nifedipine and ritodrine for preterm labor

Papatsonis DN et al., 2000 Obstetrics and Gynecology

OBJECTIVE: We compared nifedipine and ritodrine for treatment of preterm labor with respect to neonatal outcome. METHODS: We conducted an open randomized multicenter study of neonatal outcome in 185 ...

Pregnancy > Preterm Labor > Tocolytic TherapyPregnancy > Preterm Labor > Neonatal OutcomesResearch Methodology > Randomized Controlled Trials > Multicenter Studies

A fixed formula to define the fertile window of the menstrual cycle as the basis of a simple method of natural family planning

Sinai I et al., 2000 Contraception

A significant number of women worldwide use periodic abstinence as their method of family planning. Many of them use some type of calendar-based approach to determine when they should abstain from unp...

Fertility Awareness > Methods > Standard Days MethodFertility Awareness > Efficacy > Theoretical EffectivenessMenstrual Cycle > Fertile Window > Identification Methods

Efficacy and safety of oral estriol for managing postmenopausal symptoms

Takahashi K et al., 2000 Maturitas

OBJECTIVE: to assess the therapeutic efficacy and safety of oral estriol for the treatment of climacteric symptoms in postmenopausal women. METHODS: 68 postmenopausal women with climacteric symptoms ...

Perimenopause/Menopause > Hormone Therapy > EstriolPerimenopause/Menopause > Symptoms > Hot FlushesPerimenopause/Menopause > Safety > Endometrial Effects

Ectopic pregnancy

Tenore JL, 2000 American Family Physician

Ectopic pregnancy occurs at a rate of 19.7 cases per 1,000 pregnancies in North America and is a leading cause of maternal mortality in the first trimester. Greater awareness of risk factors and impro...

General OB/GYN > Ectopic Pregnancy > DiagnosisGeneral OB/GYN > Ectopic Pregnancy > ManagementDiagnostics > Biomarkers > hCG and Progesterone

Reproductive features in women developing ovarian granulosa cell tumour at a fertile age

Unkila-Kallio L et al., 2000 Human Reproduction (Oxford, England)

Ovarian granulosa cell tumour (GCT) is a rare malignancy, which has been linked to both infertility and infertility treatment with ovulation inducers. The reproductive features were analysed of 146 wo...

Infertility > Complications > Ovarian TumorsGeneral OB/GYN > Ovarian Pathology > Granulosa Cell TumorsInfertility > Ovulation Induction > Long-term Risks

Augmented trochanteric bone mineral density after modified physical education classes: a randomized school-based exercise intervention study in prepubescent and early pubescent children

H A McKay et al., 2000 The Journal of Pediatrics

Background: Of the few exercise intervention studies focusing on pediatric populations, none have confined the intervention to the scheduled physical education curriculum. Objective: To examine the e...

Bone Health > Pediatric > Exercise InterventionsBone Health > Bone Mineral Density > Physical Activity EffectsResearch Methodology > Randomized Controlled Trials > School-Based Interventions

Postfertilization effects of oral contraceptives and their relationship to informed consent

Larimore WL et al., 2000 Archives of family medicine

The primary mechanism of oral contraceptives is to inhibit ovulation, but this mechanism is not always operative. When breakthrough ovulation occurs, then secondary mechanisms operate to prevent clini...

Contraception/Comparison > Oral Contraceptives > Mechanism of ActionEthics/Philosophy > Informed Consent > Contraceptive CounselingContraception/Comparison > Oral Contraceptives > Postfertilization Effects

Ureteral displacement associated with pelvic peritoneal defects and endometriosis

Nackley AC et al., 2000 The Journal of the American Association of Gynecologic Laparoscopists

Ten women had endometriosis and pelvic peritoneal defects of the posterior leaf of the broad ligament, with the consistent finding of medial displacement of the ureter toward the uterosacral ligament....

Endometriosis > Surgical Management > UreterolysisEndometriosis > Anatomy > Peritoneal DefectsSurgery > Complications > Ureteral Injury Prevention

Use of ethinyl estradiol to reverse the antiestrogenic effects of clomiphene citrate in patients undergoing intrauterine insemination: a comparative, randomized study

Gerli S et al., 2000 Fertility and Sterility

OBJECTIVE: To compare the effectiveness of clomiphene citrate used alone and in combination with ethinyl E2 for the induction of ovulation in patients undergoing IUI. DESIGN: Randomized, double-blind...

Infertility > Ovulation Induction > Clomiphene CitrateInfertility > Treatment > Intrauterine InseminationReproductive Endocrinology > Endometrial Development > Estrogen Supplementation

Cervical Cerclage: Green-top Guideline No. 75

Hilgers TW, 2000 BJOG : an international journal of obstetrics and gynaecology

This is the second edition of this guideline; the first edition was published in 2011 under the same name. It supplements NICE guideline NG25 Preterm labour and birth. Cerclage remains one of the stan...

Pregnancy > Preterm Birth > Cervical CerclageSurgery > Gynecologic Procedures > Cervical CerclageGeneral OB/GYN > Clinical Guidelines > Preterm Birth Prevention

Successful induction of ovulation using highly purified follicle-stimulating hormone in a woman with Kallmann's syndrome

Battaglia C et al., 2000 Fertility and sterility

OBJECTIVE: To describe a woman with Kallmann's syndrome who was treated successfully with highly purified FSH to achieve ovulation induction and pregnancy. DESIGN: Case report. SETTING: University h...

Infertility > Ovulation Induction > Kallmann SyndromeReproductive Endocrinology > Hypogonadotropic Hypogonadism > FSH TherapyNaProTECHNOLOGY > Medical Treatments > Gonadotropin Therapy

The prognostic role of salpingoscopy in laparoscopic tubal surgery

Marana R et al., 1999 Human Reproduction (Oxford, England)

The present study was designed to evaluate the prognostic value of salpingoscopy in patients undergoing tubal laparoscopic surgery for infertility due to periadnexal adhesion or distal tubal occlusion...

Surgery > Tubal Surgery > SalpingoscopyInfertility > Tubal Factor > Surgical Treatment OutcomesDiagnostics > Endoscopy > Salpingoscopic Assessment

Clinical efficacy of an automated high-sensitivity C-reactive protein assay

Rifai N et al., 1999 Clinical Chemistry

BACKGROUND: Prospective studies have shown that C-reactive protein (CRP) can be used to predict risk of future cardiovascular events. High-sensitivity methods for CRP (hs-CRP) measurement are needed f...

Diagnostics > Biomarkers > C-Reactive ProteinResearch Methodology > Assay Validation > Clinical Efficacy Comparison

Diagnostic laparoscopy in infertile women with normal hysterosalpingograms

al-Badawi IA et al., 1999 The Journal of Reproductive Medicine

OBJECTIVE: To assess the value of laparoscopy in infertile women with normal hysterosalpingograms, with and without risk factors suggesting pelvic disease. STUDY DESIGN: We retrospectively reviewed 1...

Infertility > Diagnostics > LaparoscopyEndometriosis > Diagnosis > Laparoscopic FindingsDiagnostics > Imaging > Hysterosalpingography Limitations

Induced abortion and subsequent pregnancy duration

Zhou W et al., 1999 Obstetrics and Gynecology

OBJECTIVE: To examine whether induced abortion influences subsequent pregnancy duration. METHODS: Women who had their first pregnancies during 1980, 1981, and 1982 were identified in three Danish nat...

Pregnancy > Preterm Birth > Risk FactorsPregnancy > Outcomes > Effects of Prior AbortionGeneral OB/GYN > Reproductive History > Abortion Consequences

Live-birth rates and multiple-birth risk using in vitro fertilization

Schieve LA et al., 1999 JAMA

CONTEXT: To maximize birth rates, physicians who perform in vitro fertilization (IVF) often transfer multiple embryos, but this increases the multiple-birth risk. Live-birth and multiple-birth rates m...

Infertility > ART Outcomes > IVF Live Birth RatesInfertility > ART Outcomes > Multiple Birth RiskContraception/Comparison > ART Risks > Multiple Pregnancy

The cost of infertility evaluation and therapy: findings of a self-insured university healthcare plan

Stovall DW et al., 1999 Fertility and Sterility

OBJECTIVE: To assess the total costs of infertility coverage, determine the proportion of healthcare costs related to infertility, compare infertility costs to those of other diseases, and calculate a...

Infertility > Health Economics > Cost of TreatmentInfertility > ART Outcomes > Insurance Coverage AnalysisResearch Methodology > Health Economics > Cost Analysis

Prevalence of polycystic ovary syndrome in women seeking treatment from community electrologists. Alabama Professional Electrology Association Study Group

Farah L et al., 1999 The Journal of Reproductive Medicine

OBJECTIVE: To determine the prevalence of the polycystic ovary syndrome (PCOS) among women seeking electrology, clients presenting to nine electrology centers completed a questionnaire. STUDY DESIGN:...

PCOS > Epidemiology > Prevalence StudiesPCOS > Diagnosis > Screening and DetectionReproductive Endocrinology > Hyperandrogenism > Community Screening

The effect of reproductive history on future pregnancy outcomes

Whitley E et al., 1999 Human Reproduction (Oxford, England)

The aim of this study was to examine the separate and joint effects of previous pregnancy history, year of pregnancy outcome, maternal age, height, smoking and fertility on risk of fetal death. Data w...

Infertility > Outcomes > Fetal Loss RiskPregnancy > Complications > Recurrent Pregnancy LossGeneral OB/GYN > Reproductive History > Predictors of Outcome

Tocolytics for preterm labor: a systematic review

Gyetvai K et al., 1999 Obstetrics and Gynecology

OBJECTIVE: To examine the effectiveness of any tocolytic compared with a placebo or no tocolytic for preterm labor. DATA SOURCES: We checked MEDLINE (1966-1998) and the Cochrane Controlled Trials Reg...

Pregnancy > Preterm Birth > Tocolytic TherapyResearch Methodology > Systematic Review > Meta-AnalysisPregnancy > Complications > Preterm Labor Management

Correlation between endometriosis and pelvic pain

Porpora MG et al., 1999 The Journal of the American Association of Gynecologic Laparoscopists

STUDY OBJECTIVE: To evaluate the relationship between prevalence and severity of chronic pelvic pain (CPP) and stage, site, and type of endometriosis. DESIGN: Prospective, observational study (Canadi...

Endometriosis > Symptoms > Pelvic Pain CorrelationEndometriosis > Classification > Deep Infiltrating EndometriosisEndometriosis > Diagnosis > Laparoscopic Assessment

Physicians' knowledge and practices regarding natural family planning

Stanford JB et al., 1999 Obstetrics and Gynecology

OBJECTIVE: To assess physicians' knowledge and practices of modern methods of natural family planning. METHODS: A questionnaire was mailed to 840 physicians selected randomly from Missouri state lice...

Fertility Awareness > Provider Education > Physician KnowledgeBody Literacy > Education > Healthcare Provider AwarenessFertility Awareness > Methods > Natural Family Planning Effectiveness

Physiciansʼ Knowledge and Practices Regarding Natural Family Planning

Stanford JB et al., 1999 Obstetrics & Gynecology

In Brief Objective To assess physicians' knowledge and practices of modern methods of natural family planning. Methods A questionnaire was mailed to 840 physicians selected randomly from Missouri stat...

Body Literacy > Education > Physician Knowledge and PracticesFertility Awareness > Provider Education > Counseling GapsFertility Awareness > Methods > NFP Effectiveness Perception

What is the best strategy for presenting ART results? A controversial comment

Driscoll GL et al., 1999 Journal of Assisted Reproduction and Genetics

Doctors love conventions. They have them in exotic places and they frequently use them to defend what would otherwise be inexplicable calculations. Thus 38 weeks of true gestation is, of course, 40 we...

InfertilityResearch MethodologyEthics/Philosophy

Endometriosis ascites: a case report

Samora-Mata J et al., 1999 JSLS : Journal of the Society of Laparoendoscopic Surgeons

This is a case presentation of an usual nature, a 43-year-old Hispanic female, multigravida presenting with physical findings of massive ascites. In most instances, the presence of massive ascites is ...

Endometriosis > Clinical Presentation > Rare ComplicationsEndometriosis > Diagnostics > Differential DiagnosisGeneral OB/GYN > Case Reports > Unusual Presentations

Antibiotic use in pregnancy and drug-resistant infant sepsis

Mercer BM et al., 1999 American Journal of Obstetrics and Gynecology

OBJECTIVE: We sought to evaluate the effect of antepartum and intrapartum antibiotic use on antimicrobial-resistant neonatal sepsis. STUDY DESIGN: We analyzed perinatal outcomes for 8474 pregnancies ...

Pregnancy > Complications > Neonatal SepsisPregnancy > Pharmacology > Antibiotic UseResearch Methodology > Observational Studies > Retrospective Cohort

Phantom endometriosis of the sciatic nerve

Fedele L et al., 1999 Fertility and Sterility

OBJECTIVE: To assess the efficacy and diagnostic value of GnRH agonist (GnRH-a) therapy in cases of hidden sciatic nerve endometriosis. DESIGN: Case report. SETTING: Academic tertiary referral cente...

Endometriosis > Clinical Presentation > Sciatic Nerve InvolvementEndometriosis > Medical Treatment > GnRH AgonistsDiagnostics > Imaging Limitations > Endometriosis Detection

Prediction of preterm delivery with transvaginal ultrasonography of the cervix in patients with high-risk pregnancies: does cerclage prevent prematurity?

Berghella V et al., 1999 American Journal of Obstetrics and Gynecology

OBJECTIVES: We sought to determine the predictive accuracy for preterm delivery of transvaginal ultrasonography of the cervix between 14 and 24 weeks' gestation in high-risk patients and to determine ...

Pregnancy > Preterm Delivery > Prediction and ScreeningPregnancy > Interventions > Cervical CerclageDiagnostics > Ultrasonography > Cervical Length Measurement

A critical woman-centred review of Is Menstruation Obsolete? By Coutinho and Segal

Hitchcock CL et al., 1999

Is Menstruation Obsolete? argues that regular monthly bleeding is not the “natural” state of women, and that it actually places them at risk of several medical conditions of varying severity. The auth...

Contraception/Comparison > FABM vs Hormonal > Side EffectsBody Literacy > Patient Empowerment > Informed Decision-MakingEthics/Philosophy > RRM Philosophy > Paradigm

Effect of prenatal care on infant mortality rates according to birth-death certificate files

Poma PA, 1999 Journal of the National Medical Association

Infant mortality has decreased nationwide; however, our national rates still log behind those of other industrialized countries, especially the rates for minority groups. This study evaluates the effe...

Pregnancy > Prenatal Care > Infant MortalityPregnancy > Outcomes > Health DisparitiesResearch Methodology > Epidemiology > Linked Birth-Death Records

Is adolescent pregnancy associated with adverse perinatal outcome?

Orvos H et al., 1999 Journal of Perinatal Medicine

BACKGROUND: The number of teenage pregnancies has increased throughout the world and these pregnancies are reported in association with a higher rate of maternal and fetal complications. AIM OF THE S...

Perimenopause/Menopause > Hormone Therapy > Cardiovascular EffectsPerimenopause/Menopause > Medical Treatment > Estrogen ReplacementReproductive Endocrinology > Estrogen > Vascular Pharmacology

Cardiovascular pharmacology of hormone replacement therapy

Rosano GM et al., 1999 Drugs & Aging

The incidence of cardiovascular disease in women is negligible before natural or surgically-induced menopause, and increases after menopause. Epidemiological data suggest that estrogen replacement the...

Pregnancy > Complications > Adolescent PregnancyPregnancy > Outcomes > Perinatal Morbidity and MortalityGeneral OB/GYN > Prenatal Care > High-Risk Populations

Pregnancy probabilities during use of the Creighton Model Fertility Care System

Howard MP et al., 1999 Archives of Family Medicine

OBJECTIVE: To evaluate pregnancy probabilities during use of the Creighton Model Fertility Care System (CrMS). DESIGN: Couples who began use of the CrMS were entered into this observational cohort st...

NaProTECHNOLOGY > Creighton Model > Effectiveness StudiesFertility Awareness > Method Effectiveness > Pregnancy ProbabilitiesResearch Methodology > Observational Studies > Life Table Analysis

Women's satisfaction with birth control: a population survey of physical and psychological effects of oral contraceptives, intrauterine devices, condoms, natural family planning, and sterilization among 1466 women

Oddens BJ, 1999 Contraception

User satisfaction and the physical and psychological effects of five commonly used contraceptive methods were investigated in a population survey among 1466 West German women. The focus was on effects...

Contraception/Comparison > User Experience > Satisfaction SurveysContraception/Comparison > Side Effects > Physical and PsychologicalFertility Awareness > User Experience > Comparison with Other Methods

The influence of donated gametes on the incidence of hypertensive disorders of pregnancy

Salha O et al., 1999 Human Reproduction (Oxford, England)

Pregnancies achieved from oocyte, sperm or embryo donation are unique, since they have resulted from donor gametes that are immunologically foreign to the mother. Thus, studying the obstetric outcome ...

Pregnancy > Complications > Hypertensive DisordersInfertility > Assisted Reproduction > Donor Gamete OutcomesPregnancy > Pathophysiology > Immunological Factors in Preeclampsia

Are all contraceptive failures unintended pregnancies? Evidence from the 1995 National Survey of Family Growth

Trussell J et al., 1999 Family planning perspectives

Context: The incidence of unintended pregnancy has long been used as a primary indicator of the state of reproductive health. However, the definition--and therefore the measurement--of this indicator ...

Contraception/Comparison > Contraceptive Failure > Measurement and ClassificationResearch Methodology > Survey Studies > National Survey of Family GrowthGeneral OB/GYN > Reproductive Health > Pregnancy Intendedness