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A comparison of the ovulation method with the CUE ovulation predictor in determining the fertile period

Fehring RJ, 1996 Journal of the American Academy of Nurse Practitioners

The purpose of this study was to compare the CUE Ovulation Predictor with the ovulation method in determining the fertile period. Eleven regularly ovulating women measured their salivary and vaginal e...

Fertility Awareness > Methods > Electronic Fertility MonitorsFertility Awareness > Methods > Cervical Mucus MonitoringBody Literacy > Ovulation Detection > Device Comparison

Prevention and management of osteoporosis: consensus statements from the Scientific Advisory Board of the Osteoporosis Society of Canada. 5. Physical activity as therapy for osteoporosis

J C Prior et al., 1996 CMAJ

Objective: To examine exercise as a therapy for people with osteoporosis. Options: Immobilization, standing low-load and high-load physical activities. Outcomes: Risk of injury, quality of life, risk...

Bone Health > Osteoporosis > Exercise TherapyBone Health > Osteoporosis > Consensus GuidelinesPerimenopause/Menopause > Bone Health > Physical Activity Interventions

Treatment of skin aging with topical estrogens

Schmidt JB et al., 1996 International Journal of Dermatology

BACKGROUND: The coincidence of climacteric symptoms and the beginning of skin aging suggests that estrogen deficiency may be a common and important factor in the perimenopausal woman. Often hormones h...

General OB/GYN > Dermatology > Estrogen and Skin AgingPerimenopause/Menopause > Hormone Therapy > Topical EstrogenReproductive Endocrinology > Estrogen > Topical Applications

Prevention of preterm birth. Role of daily telephone contact

Boehm FH et al., 1996 The Journal of Reproductive Medicine

OBJECTIVE: To compare the effectiveness of routine management of patients at high risk for preterm delivery to the effectiveness of routine management in combination with daily telephone nursing conta...

Pregnancy > Preterm Birth > Prevention StrategiesPregnancy > High-Risk Management > Telephone Nursing SupportResearch Methodology > Intervention Studies > Nonrandomized Trials

The efficacy of 250 mg/day flutamide in the treatment of patients with hirsutism

Bayram F et al., 1996 Fertility and Sterility

OBJECTIVE: To investigate the effects of low dose flutamide (250 mg/d) on hirsutism score and hormone levels in women with hirsutism. DESIGN: Nonrandomized, prospective clinical trial. PATIENTS: For...

Reproductive Endocrinology > Androgens > Antiandrogen TherapyPCOS > Treatment > Hirsutism ManagementGeneral OB/GYN > Hirsutism > Pharmacological Treatment

The significance of transvaginal ultrasonographic evaluation of the cervix in women treated with emergency cerclage

Guzman ER et al., 1996 American Journal of Obstetrics and Gynecology

OBJECTIVE: Our purpose was to determine whether perioperative transvaginal ultrasonographic evaluation of the incompetent cervix treated with emergency cerclage is predictive of pregnancy outcome. ST...

Pregnancy > Cervical Incompetence > Emergency CerclageDiagnostics > Transvaginal Ultrasound > Cervical AssessmentPregnancy > Preterm Birth > Cerclage Outcomes

Transvaginal ultrasound and preterm prelabor: a nonrandomized intervention study

Zalar RW Jr, 1996 Obstetrics and Gynecology

OBJECTIVE: To characterize the continuum between normal and preterm labor to prevent spontaneous preterm birth and low birth weight. METHODS: Between August 1, 1992, and November 30, 1993, obstetric ...

Pregnancy > Preterm Birth > Screening and PreventionDiagnostics > Transvaginal Ultrasound > Cervical Length ScreeningPregnancy > Preterm Birth > Outpatient Tocolysis Management

ACOG technical bulletin. Chronic pelvic pain. Number 223--May 1996 (replaces no. 129, June 1989). American College of Obstetricians and Gynecologists

Committee on Technical Bulletins of the American College of Obstetricians and Gynecologists, 1996 International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

Although treating patients with chronic pelvic pain may pose a challenge, such patients can often be treated successfully. Effective modalities are available to lessen the impact of the pain and offer...

General OB/GYN > Pelvic Pain > Chronic Pelvic PainGeneral OB/GYN > Clinical Guidelines > ACOG RecommendationsDiagnostics > Gynecologic Evaluation > Pelvic Pain Assessment

Menstrual and reproductive factors and hip fractures in post menopausal women

Parazzini F et al., 1996 Maturitas

Objectives: We analyzed the relationship between menstrual and reproductive history and risk of hip fractures in post-menopausal women using data from an Italian case-control study. Methods: Cases we...

Perimenopause/Menopause > Bone Health > Hip Fracture RiskBone Health > Risk Factors > Reproductive HistoryResearch Methodology > Study Design > Case-Control Study

Effect of estriol on bone loss in postmenopausal Japanese women: a multicenter prospective open study

Minaguchi H et al., 1996 The Journal of Obstetrics and Gynaecology Research

OBJECTIVES: To assess the effects of oral estriol on the bone mineral density (BMD) and bone metabolism in postmenopausal women. METHODS: Seventy-five natural postmenopausal women with a BMD of more ...

Perimenopause/Menopause > Hormone Therapy > EstriolBone Health > Treatment > Estrogen TherapyPerimenopause/Menopause > Symptoms > Climacteric Management

Risk factors, falls, and fracture of the distal forearm in Manchester, UK

O'Neill TW et al., 1996 Journal of Epidemiology and Community Health

Objective: To determine the risk factors associated with fracture of the distal forearm, and to evaluate the influence of falls on these risks. Design: This was a case-control study. Setting: Manchest...

Bone HealthPerimenopause/Menopause

Pregnancy and the timing of intercourse

Hilgers TW, 1996 The New England Journal of Medicine

The optimal timing of sexual intercourse in relation to the day of ovulation in order for pregnancy to result is a topic of broad interest. Of obvious relevance to fecundability, on the one hand, a...

Fertility Awareness > Fertile Window > Intercourse TimingInfertility > Natural Approaches > Timed IntercourseNaProTECHNOLOGY > Fertility Optimization > Ovulation Timing

Hypothalamic corticotropin-releasing hormone suppression during the postpartum period: implications for the increase in psychiatric manifestations at this time

Magiakou MA et al., 1996 The Journal of Clinical Endocrinology and Metabolism

The third trimester of human pregnancy is characterized by a hyperactive hypothalamic-pituitary-adrenal axis, possibly driven by progressively increasing circulating levels of placental CRH and gradua...

Postpartum > Mental Health > Postpartum DepressionReproductive Endocrinology > HPA Axis > CRH SuppressionPregnancy > Neuroendocrinology > Hypothalamic-Pituitary-Adrenal Axis

The preterm prediction study: fetal fibronectin testing and spontaneous preterm birth. NICHD Maternal Fetal Medicine Units Network

Goldenberg RL et al., 1996 Obstetrics and Gynecology

OBJECTIVE: To evaluate the presence of fetal fibronectin in the cervix and vagina as a screening test for spontaneous preterm birth. METHODS: Two thousand nine hundred twenty-nine women at ten center...

Pregnancy > Preterm Birth > Screening BiomarkersDiagnostics > Prenatal Screening > Preterm Risk AssessmentPregnancy > Risk Stratification > Fetal Fibronectin

Effect of oral estradiol on Lp(a) and other lipoproteins in postmenopausal women. A randomized, double-blind, placebo-controlled, crossover study

Haines C et al., 1996 Archives of Internal Medicine

BACKGROUND: Lp(a) lipoprotein level is an independent risk factor for premature coronary artery disease and cerebrovascular accident. Concentrations of this lipoprotein tend to increase after menopaus...

Perimenopause/Menopause > Cardiovascular Health > Lipid ManagementPerimenopause/Menopause > Hormone Therapy > Estradiol EffectsPerimenopause/Menopause > Disease Prevention > Cardiovascular

Transdermal oestrogen for treatment of severe postnatal depression

Gregoire AJ et al., 1996 Lancet (London, England)

BACKGROUND: Postnatal depression can have long-term adverse consequences for the mother, for the marital relationship, and for the infant's psychological development. Such depressions can be severe an...

Postpartum > Mental Health > Postpartum Depression TreatmentReproductive Endocrinology > Hormone Therapy > Estrogen as AntidepressantResearch Methodology > Study Design > Randomized Double-Blind Placebo-Controlled Trial

Delay in the diagnosis of endometriosis: a survey of women from the USA and the UK

Hadfield R et al., 1996 Human Reproduction (Oxford, England)

We investigated the length of time between the onset of pain symptoms and the surgical diagnosis of endometriosis in women from the UK and the USA. A total of 218 women with surgically confirmed disea...

Endometriosis > Diagnosis > Diagnostic DelayEndometriosis > Epidemiology > Patient Experience SurveysResearch Methodology > Study Design > Cross-Sectional Survey

Donor insemination: a comparison of lesbian couples, heterosexual couples and single women

Wendland CL et al., 1996 Fertility and Sterility

OBJECTIVE: To compare single women, lesbian couples, and heterosexual couples receiving therapeutic donor insemination (TDI). DESIGN: Chart review followed by anonymous mail questionnaires to donor i...

General OB/GYN > Assisted Reproduction > Donor InseminationEthics/Philosophy > Reproductive Ethics > Donor Conception DisclosureInfertility > Treatment > Therapeutic Donor Insemination

Clomiphene citrate with intrauterine insemination: is it effective therapy in women above the age of 35 years?

Agarwal SK et al., 1996 Fertility and Sterility

OBJECTIVES: To evaluate the influence of female age on clomiphene citrate (CC) with IUI therapy and to compare the efficacy of this therapy between patients with ovulatory and anovulatory infertility....

Infertility > Ovulation Induction > Clomiphene CitrateInfertility > Intrauterine Insemination > Age-Related OutcomesInfertility > Prognostic Factors > Maternal Age

Scientific bases for NFP beyond question

Kippley JF, 1996 CCL Family Foundations

The Couple to Couple League (CCL) is pleased that an article and an editorial in the December 1995 issue of the well-respected New England Journal of Medicine confirm that natural family planning (NFP...

Fertility Awareness > Methods > Cervical Mucus MonitoringFertility Awareness > Efficacy > Scientific BasisMenstrual Cycle > Ovulation > Fertile Window Identification

Ovulatory premenopausal women lose cancellous spinal bone: a five year prospective study

J C Prior et al., 1996 Bone

Healthy premenopausal women with regular cycles are believed to be increasing or maintaining bone density. However, few studies have prospectively documented spinal cancellous bone, the bone that chan...

Bone Health > Premenopausal Bone Loss > Ovulatory DisturbancesMenstrual Cycle > Luteal Phase > Subclinical DefectsReproductive Endocrinology > Progesterone > Bone Metabolism

A prospective controlled study of luteal and endometrial abnormalities in an infertile population

Batista MC et al., 1996 Fertility and Sterility

OBJECTIVE: To investigate whether luteal and endometrial abnormalities occur more frequently in an infertile population and thus contribute to infertility. DESIGN: Prospective controlled clinical stu...

Infertility > Endometrial Factors > Luteal Phase DefectDiagnostics > Endometrial Biopsy > Histologic DatingReproductive Endocrinology > Corpus Luteum > Progesterone Secretion

Relationship between symptom severity and steroid variation in women with premenstrual syndrome: study on serum pregnenolone, pregnenolone sulfate, 5 alpha-pregnane-3,20-dione and 3 alpha-hydroxy-5 alpha-pregnan-20-one

Wang M et al., 1996 The Journal of Clinical Endocrinology and Metabolism

The relationship between symptoms of premenstrual syndrome (PMS) and serum levels of pregnenolone (Pe), pregnenolone sulfate (PS), 5 alpha-pregnane-3,20-dione (5 alpha-DHP), 3 alpha-hydroxy-5 alpha- p...

Reproductive Endocrinology > Steroid Hormones > Progesterone MetabolitesMenstrual Cycle > Premenstrual Syndrome > Hormonal CorrelatesGeneral OB/GYN > Premenstrual Disorders > Neuroactive Steroids

Endometrial progesterone receptors and markers of uterine receptivity in the window of implantation

Lessey BA et al., 1996 Fertility and Sterility

OBJECTIVE: To compare the expression of endometrial P receptors (PR) levels with markers of endometrial receptivity during the window of implantation. DESIGN: Prospective, controlled study to examine...

Infertility > Endometrial Factors > Implantation ReceptivityReproductive Endocrinology > Progesterone > Receptor ExpressionInfertility > Luteal Phase Defect > Endometrial Markers

The length of the cervix and the risk of spontaneous premature delivery. National Institute of Child Health and Human Development Maternal Fetal Medicine Unit Network

Iams JD et al., 1996 The New England Journal of Medicine

BACKGROUND: The role of the cervix in the pathogenesis of premature delivery is controversial. In a prospective, multicenter study of pregnant women, we used vaginal ultrasonography to measure the len...

Pregnancy > Preterm Birth > Cervical Length ScreeningDiagnostics > Ultrasound > Transvaginal Cervical MeasurementPregnancy > Risk Assessment > Preterm Delivery Prediction

The corpus luteum insufficiency: a multifactorial disease

Hinney B et al., 1996 The Journal of Clinical Endocrinology and Metabolism

The pulsatile release pattern of LH during the entire menstrual cycle is well defined; however, the response of corpora lutea to these LH pulses in patients suffering from corpus luteum insufficiencie...

Reproductive Endocrinology > Corpus Luteum > Insufficiency ClassificationInfertility > Luteal Phase Defect > PathophysiologyReproductive Endocrinology > LH Secretion > Pulsatile Patterns

Maternal blood C-reactive protein, white blood cell count, and temperature in preterm labor: a comparison with amniotic fluid white blood cell count

Yoon BH et al., 1996 Obstetrics and Gynecology

OBJECTIVE: To compare the diagnostic and prognostic performance of maternal blood C-reactive protein, white blood cell count (WBC), and temperature with that of amniotic fluid (AF) WBC in preterm labo...

Pregnancy > Preterm Birth > Intrauterine Infection MarkersDiagnostics > Biomarkers > Chorioamnionitis DetectionPregnancy > Complications > Chorioamnionitis

Field trial of billings ovulation method of natural family planning

Bhargava H et al., 1996 Contraception

There are couples with unmet family planning needs and couples who do not use any modern method, yet they desire to space or avoid pregnancies. Many of them look for safe and effective options like th...

Fertility Awareness > Methods > Billings Ovulation MethodFertility Awareness > Efficacy > Use-Effectiveness StudiesBody Literacy > Cervical Mucus > Fertility Monitoring

Follistatins neutralize activin bioactivity by inhibition of activin binding to its type II receptors

de Winter JP et al., 1996 Molecular and Cellular Endocrinology

Follistatin is an activin-binding protein, which inhibits activin bioactivity in several biological systems. In the present study it is demonstrated that preincubation of iodinated activin A with foll...

Reproductive Endocrinology > Activin-Follistatin System > Receptor Binding MechanismsReproductive Endocrinology > Molecular Signaling > Growth Factor RegulationResearch Methodology > In Vitro Studies > Cell Transfection Assays

Polycystic ovary syndrome: pathophysiology and outcome with in vitro fertilization

Buyalos RP et al., 1996 Fertility and Sterility

OBJECTIVE: To assess the efficacy of IVP-ET in infertile women with the polycystic ovary syndrome (PCOS) and to provide a comprehensive review of contemporary therapeutic options and their complicatio...

PCOS > Treatment > In Vitro Fertilization OutcomesInfertility > Assisted Reproduction > IVF in PCOSPCOS > Complications > Ovarian Hyperstimulation Syndrome

Correlation between cytokine levels of amniotic fluid and histological chorioamnionitis in preterm delivery

Negishi H et al., 1996 Journal of Perinatal Medicine

The aim of this study was to investigate the correlation between the cytokine levels in the amniotic fluid (AF) and the histological stage of chorioamnionitis (CAM) in premature labor. AF of 6 cases (...

Pregnancy > Preterm Labor > Chorioamnionitis BiomarkersDiagnostics > Biomarkers > Amniotic Fluid CytokinesPregnancy > Complications > Intraamniotic Infection

Low and conventional dose transdermal oestradiol are equally effective at preventing bone loss in spine and femur at all post-menopausal ages

Evans SF et al., 1996 Clinical Endocrinology

OBJECTIVES: We wished to appraise the effectiveness of hormone replacement therapy (HRT) in early (< 67 years) and late (> 67 years) post-menopausal women referred to a metabolic outpatient clinic for...

Perimenopause/Menopause > Hormone Replacement Therapy > Transdermal EstradiolBone Health > Osteoporosis Prevention > HRT Dose ComparisonPerimenopause/Menopause > Bone Health > BMD Outcomes

Effect of different progestagens in low oestrogen oral contraceptives on venous thromboembolic disease. World Health Organization Collaborative Study of Cardiovascular Disease and Steroid Hormone Contraception

No Authors Listed, 1995 Lancet (London, England)

A multinational hospital-based case-control study of the risk of venous thromboembolic disease associated with combined oral contraceptives (OCs) done in 1989-93 prompted a separate inquiry comparing ...

Contraception/Comparison > Oral Contraceptives > Progestagen Type and VTE RiskContraception/Comparison > Adverse Effects > Venous ThromboembolismResearch Methodology > Epidemiology > Case-Control Studies

Enhancement by factor V Leiden mutation of risk of deep-vein thrombosis associated with oral contraceptives containing a third-generation progestagen

Bloemenkamp KW et al., 1995 Lancet (London, England)

Recent concern about the safety of combined oral contraceptives (OCs) with third-generation progestagens prompted an examination of data from a population-based case-control study (Leiden Thrombophili...

Contraception/Comparison > Adverse Effects > Venous ThromboembolismContraception/Comparison > Oral Contraceptives > Genetic Risk FactorsDiagnostics > Thrombophilia > Factor V Leiden and Contraception

Venous thromboembolic disease and combined oral contraceptives: results of international multicentre case-control study. World Health Organization Collaborative Study of Cardiovascular Disease and Steroid Hormone Contraception

No Authors Listed, 1995 Lancet (London, England)

The composition and use of oral contraceptives (OCs) have changed since their cardiovascular side-effects were established 20 years ago. This report describes the risk of idiopathic venous thromboembo...

Contraception/Comparison > Adverse Effects > Venous ThromboembolismContraception/Comparison > Oral Contraceptives > International Risk AssessmentResearch Methodology > Epidemiology > Multinational Case-Control Studies

Risk of idiopathic cardiovascular death and nonfatal venous thromboembolism in women using oral contraceptives with differing progestagen components

Jick H et al., 1995 Lancet (London, England)

Concern about the risks of cardiovascular illness in women using combined oral contraceptives (OC) containing the progestagens desogestrel and gestodene prompted two studies of data from the UK Genera...

Contraception/Comparison > Adverse Effects > Venous ThromboembolismContraception/Comparison > Oral Contraceptives > Progestagen Type and Cardiovascular RiskResearch Methodology > Epidemiology > Cohort and Nested Case-Control Studies

Prophylactic estrogen in recurrent postpartum affective disorder

Sichel DA et al., 1995 Biological Psychiatry

Seven women with histories of puerperal psychosis and four with histories of puerperal major depression were consecutively treated with high-dose oral estrogen immediately following delivery. None of ...

Postpartum > Mental Health > Postpartum Psychosis PreventionPostpartum > Hormonal Interventions > Estrogen ProphylaxisReproductive Endocrinology > Estrogen > Neuroendocrine Effects

Timing of sexual intercourse in relation to ovulation. Effects on the probability of conception, survival of the pregnancy, and sex of the baby

Wilcox AJ et al., 1995 The New England Journal of Medicine

BACKGROUND: The timing of sexual intercourse in relation to ovulation strongly influences the chance of conception, although the actual number of fertile days in a woman's menstrual cycle is uncertain...

Fertility Awareness > Fertile Window > Timing of IntercourseInfertility > Natural Conception > Conception ProbabilityMenstrual Cycle > Ovulation Detection > Urinary Hormone Metabolites

Preterm labor: emerging role of genital tract infections

Andrews WW et al., 1995 Infectious Agents and Disease

Preterm birth complicates 8-10% of all pregnancies in the United States and is the leading cause of infant morbidity and mortality. Neonatal morbidity and mortality is concentrated among very low-birt...

Pregnancy > Preterm Birth > Infection EtiologyPregnancy > Preterm Labor > Tocolytic TherapyGeneral OB/GYN > Genital Tract Infections > Preterm Birth Risk

Evidence of a distinct derangement of opioid tone in hyperinsulinemic patients with polycystic ovarian syndrome: relationship with insulin and luteinizing hormone secretion

Lanzone A et al., 1995 The Journal of Clinical Endocrinology and Metabolism

Recent data indicate that an altered opioid tone could be involved in the LH hypersecretion and metabolic alterations seen in polycystic ovary syndrome (PCOS). The aim of the present study was to inve...

PCOS > Pathophysiology > Opioid Tone DerangementPCOS > Insulin Resistance > Hyperinsulinemia and LH SecretionReproductive Endocrinology > Neuroendocrine Regulation > Opioid System

Natural family planning. An alternative

Soler F et al., 1995 Revista De Enfermeria (Barcelona, Spain)

The scientific foundations and most notable features of modern natural family planning (NFP) methods are described. NFP techniques require observation of the signs and symptoms occurring during the fe...

Fertility Awareness > Methods > Symptothermal MethodFertility Awareness > Methods > Billings Ovulation MethodContraception/Comparison > Effectiveness > NFP vs Contraceptive Methods

Outcome of pregnancies in women with treated or untreated hyperprolactinemia

Rossi AM et al., 1995 European Journal of Obstetrics, Gynecology, and Reproductive Biology

The outcome of 103 pregnancies in 64 women with constant hyperprolactinemia was evaluated. Seventy-eight pregnancies had been induced with bromocriptine and 25 occurred without any treatment. In all, ...

Reproductive Endocrinology > Hyperprolactinemia > Pregnancy OutcomesInfertility > Ovulation Induction > Bromocriptine TreatmentPregnancy > Complications > Ectopic Pregnancy

Prevention of de-novo adhesion formation after laparoscopic myomectomy: a randomized trial to evaluate the effectiveness of an oxidized regenerated cellulose absorbable barrier

Mais V et al., 1995 Human Reproduction (Oxford, England)

To evaluate the effectiveness of the oxidized regenerated cellulose absorbable barrier (Interceed, TC7) in the prevention of de-novo adhesion formation after laparoscopic myomectomy, a prospective and...

Surgery > Laparoscopic Myomectomy > Adhesion PreventionSurgery > Adhesion Barriers > Oxidized Regenerated CelluloseInfertility > Surgical Treatment > Fibroid Removal Outcomes

Naltrexone treatment restores menstrual cycles in patients with weight loss-related amenorrhea

Genazzani AD et al., 1995 Fertility and Sterility

Objective: To evaluate whether the efficacy of naltrexone administration in patients with hypothalamic amenorrhea correlates to the response to an acute naloxone test. Design: Thirty patients with hyp...

Menstrual Cycle > Amenorrhea > Hypothalamic Amenorrhea TreatmentReproductive Endocrinology > Neuroendocrine Regulation > Opioid Antagonist TherapyRRM Methods > Pharmacological Interventions > Naltrexone for Amenorrhea