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The effect of 17 alpha-hydroxyprogesterone caproate/oestradiol valerate on the development and outcome of early pregnancies following in vitro fertilization and embryo transfer: a prospective and randomized controlled trial

Prietl G et al., 1992 Human Reproduction (Oxford, England)

A prospective and randomized study was performed to investigate the effect of supportive hormones on the development and outcome of early pregnancies following in vitro fertilization and embryo transf...

Infertility > IVF > Luteal Phase SupportPregnancy > Early Pregnancy > Miscarriage PreventionReproductive Endocrinology > Progesterone > Supplementation in Early Pregnancy

Natural family planning

Odeblad E, 1992 Jordemodern

Natural family planning (NFP) is based on the knowledge *largely nonexistent) of a women as to whether she is in her fertile period or not. In contrast to the calendar method, the Billings method cons...

Fertility Awareness > Billings Ovulation Method > Biological BasisMenstrual Cycle > Cervical Mucus > Hormonal RegulationBody Literacy > Fertility Signs > Mucus Observation

Pulsatile LH secretion in women with premenstrual syndrome (PMS): evidence for normal neuroregulation of the menstrual cycle

Reame NE et al., 1992 Psychoneuroendocrinology

The premenstrual syndrome (PMS) has been proposed to result from excessive exposure to and/or withdrawal of brain opioid activity during the luteal phase. Because hypothalamic opioids are believed to ...

Reproductive Endocrinology > Gonadotropins > LH PulsatilityMenstrual Cycle > Luteal Phase > Premenstrual Syndrome PathophysiologyReproductive Endocrinology > Neuroendocrinology > Opioid Modulation

Serum levels of androgens are higher in women with premenstrual irritability and dysphoria than in controls

Eriksson E et al., 1992 Psychoneuroendocrinology

Serum levels of progesterone, total testosterone, free testosterone, androstenedione (A2), dehydroepiandrosterone (DHEA), dehydroepiandrosterone sulphate (DHEAS), 17-OH-progesterone (17-OHP), and sex ...

Menstrual Cycle > Premenstrual Syndrome > Hormonal PathophysiologyReproductive Endocrinology > Androgens > Female Androgen ExcessDiagnostics > Hormone Levels > Androgen Assessment in PMS

A review of premature birth and subclinical infection

Gibbs RS et al., 1992 American Journal of Obstetrics and Gynecology

Premature birth causes high rates of neonatal morbidity and mortality. There are multiple causes of preterm birth. This article reviews the evidence linking subclinical infection and premature birth. ...

Pregnancy > Preterm Birth > Infection-Related MechanismsPregnancy > Complications > ChorioamnionitisGeneral OB/GYN > Infectious Disease > Genital Tract Infections in Pregnancy

Pain symptoms associated with endometriosis

Fedele L et al., 1992 Obstetrics and Gynecology

We evaluated the prevalence and severity of dysmenorrhea, pelvic pain, and deep dyspareunia and their relation to disease stage and site in 124 infertile women with endometriosis and 67 infertile wome...

Endometriosis > Symptoms > Pain AssessmentEndometriosis > Classification > Disease Staging and Pain CorrelationGeneral OB/GYN > Pelvic Pain > Endometriosis-Related

Association between infertility and spontaneous abortion

Coulam CB, 1992 American Journal of Reproductive Immunology (New York, N.Y. : 1989)

Women experiencing recurrent spontaneous abortion have a higher frequency of infertility than that expected in the general population. To further define the relationships between infertility and spont...

Infertility > Unexplained Infertility > Association with Pregnancy LossPregnancy > Recurrent Pregnancy Loss > Risk FactorsInfertility > Secondary Infertility > Obstetrical Outcomes

Comparison of the peritoneal cells elicited by oxidized regenerated cellulose (Interceed) and expanded polytetrafluoroethylene (Gore-Tex Surgical Membrane) in a murine model

Haney AF et al., 1992 American Journal of Obstetrics and Gynecology

OBJECTIVE: The peritoneal fluid cell responses to the available barriers used to prevent postoperative adhesions, oxidized regenerated cellulose (interceed) and expanded polytetrafluoroethylene (Gore-...

Surgery > Adhesion Prevention > Barrier Materials ComparisonSurgery > Adhesion Prevention > Inflammatory ResponseResearch Methodology > Animal Models > Peritoneal Adhesion Studies

Prophylaxis of pelvic sidewall adhesions with Gore-Tex surgical membrane: a multicenter clinical investigation. The Surgical Membrane Study Group

Surgical Membrane Study Group, 1992 Fertility and Sterility

Eight patients with extensive adhesions and 10 undergoing myomectomy had Gore-Tex surgical membranes placed to prevent adhesion formation/reformation. At the time of second-look laparoscopy, the membr...

Surgery > Adhesion Prevention > Barrier MethodsSurgery > Myomectomy > Postoperative OutcomesInfertility > Surgical Treatment > Adhesion Management

Inhibin and activin in reproductive biology

Dye RB et al., 1992 Obstetrical & Gynecological Survey

It has become apparent in recent years that regulation of the ovulatory cycle cannot be accomplished solely through the mediation of the two pituitary gonadotropins, follicle-stimulating hormone (FSH)...

Reproductive Endocrinology > Hormonal Regulation > Inhibin and ActivinMenstrual Cycle > Physiology > Neuroendocrine ControlReproductive Endocrinology > Ovarian Function > Paracrine Signaling

Preterm delivery, low birthweight and small-for-gestational-age in liveborn singleton babies resulting from in-vitro fertilization

Doyle P et al., 1992 Human Reproduction (Oxford, England)

The Medical Research Council In-Vitro Fertilization (IVF) Register report on births resulting from assisted conception in Great Britain demonstrated a high incidence of preterm and low birthweight bab...

Pregnancy > Complications > Preterm DeliveryInfertility > Assisted Reproduction > IVF OutcomesPregnancy > Fetal Growth > Small for Gestational Age

Women with polycystic ovary syndrome wedge resected in 1956 to 1965: a long-term follow-up focusing on natural history and circulating hormones

Dahlgren E et al., 1992 Fertility and Sterility

OBJECTIVE: To determine if the hormonal imbalance in women with polycystic ovary syndrome (PCOS) continues into and after menopause and to analyze factors constituting an increased risk for developing...

PCOS > Long-term Outcomes > Metabolic ComplicationsPCOS > Surgical Treatment > Ovarian Wedge ResectionPerimenopause/Menopause > Metabolic Health > PCOS and Menopause

Diagnosis of cervical change in pregnancy by means of transvaginal ultrasonography

Joffe GM et al., 1992 American Journal of Obstetrics and Gynecology

There are no absolute objective diagnostic criteria for cervical incompetence. Abdominal and endovaginal ultrasonographic assessment of endocervical length, both of which have been associated with tec...

Pregnancy > Complications > Cervical IncompetenceDiagnostics > Ultrasound > Transvaginal Cervical AssessmentPregnancy > Preterm Birth > Cervical Length Screening

Low-dosage micronized 17 beta-estradiol prevents bone loss in postmenopausal women

Ettinger B et al., 1992 American Journal of Obstetrics and Gynecology

With the use of a double-blind, randomized, dose-ranging design, we tested during an 18-month period the degree of protection against postmenopausal bone loss afforded by micronized 17 beta-estradiol ...

Perimenopause/Menopause > Hormone Therapy > EstradiolBone Health > Osteoporosis Prevention > Estrogen TherapyBone Health > Bone Density > Calcium and Estrogen Interaction

Gonadotropin and ovarian hormone dynamics in luteal phase defects

Alexander SE et al., 1992 American Journal of Obstetrics and Gynecology

Blood samples were obtained during early follicular, periovulatory, and luteal phases in four women with out-of-phase endometrial biopsy specimens and four normal controls. In the study cycle, follicu...

Reproductive Endocrinology > Luteal Phase > Luteal Phase DefectReproductive Endocrinology > Hormonal Regulation > Gonadotropin DynamicsDiagnostics > Endometrial Biopsy > Luteal Phase Assessment

Predictive value of C-reactive protein in serum of maternal and cord blood in cases with premature rupture of membranes

Awara AM et al., 1992 Egyptian Medical Journal

Physicians compared clinical history, examination, and laboratory data on 10 pregnant women at various gestational ages with intact membranes till labor began (controls) with data on 25 pregnant women...

Pregnancy > Complications > Premature Rupture of MembranesDiagnostics > Biomarkers > C-Reactive Protein in PregnancyPregnancy > Infections > Chorioamnionitis Prediction

Endoscopic carbon dioxide laser ovarian wedge resection in resistant polycystic ovarian disease

Ostrzenski A, 1992 International journal of fertility

Clomiphene citrate therapy has been found to improve the infertility rate in women suffering from polycystic ovarian disease (PCOD). However, there still exists a group of women with PCOD who fail to ...

Surgery > Laparoscopic Procedures > Ovarian Wedge ResectionPCOS > Surgical Treatment > Laser Ovarian DrillingInfertility > Ovulation Induction Failure > Surgical Alternatives

Increased rate of preterm deliveries in untreated women with luteal phase deficiencies. Preliminary report

Check JH et al., 1992 Gynecologic and Obstetric Investigation

Some randomized studies have suggested a significant beneficial effect of 17-hydroxyprogesterone caproate in the prevention of preterm labor [1, 2], The therapy in both studies was initiated at approx...

NaProTECHNOLOGY > Progesterone Support > Preterm Delivery PreventionPregnancy > Preterm Birth > Progesterone DeficiencyReproductive Endocrinology > Luteal Phase > Luteal Phase Defect Treatment

Effect of cyclofenil on hormonal dynamics, follicular development and cervical mucus in normal and oligomenorrhoeic women

Yong EL et al., 1992 Human Reproduction (Oxford, England)

Cyclofenil is a triphenylethylene derivative, similar in structure to clomiphene citrate, which is used to induce ovulation in anovulatory women. The effects of cyclofenil on a group of 10 normal cycl...

Infertility > Ovulation Induction > CyclofenilReproductive Endocrinology > Hormonal Regulation > Gonadotropin PulsatilityGeneral OB/GYN > Oligomenorrhea > Treatment Efficacy

Randomized controlled trials of home uterine activity monitoring: a review and critique

Grimes DA et al., 1992 Obstetrics and Gynecology

Home uterine activity monitoring has been proposed as an effective technique for reducing the incidence of preterm birth by early recognition of incipient labor. Five randomized controlled trials eval...

Pregnancy > Preterm Birth > Home MonitoringResearch Methodology > Critical Appraisal > Randomized Controlled TrialsPregnancy > Preterm Birth > Prevention Strategies

The effect of ethinyl estradiol on endometrial thickness and uterine volume during ovulation induction by clomiphene citrate

Yagel S et al., 1992 Fertility and Sterility

OBJECTIVE: To assess the deleterious effect of clomiphene citrate (CC) on the development of the endometrium and its improvement by the addition of ethinyl estradiol (E2). PARTICIPATING PATIENTS: In...

Infertility > Ovulation Induction > Clomiphene CitrateInfertility > Ovulation Induction > Endometrial EffectsDiagnostics > Ultrasound > Endometrial Assessment

Visualization Techniques in Infertility

Hilgers TW, 1992 Scientific Visualization
NaProTECHNOLOGY > Diagnostics > Visualization TechniquesInfertility > Diagnosis > Imaging MethodsDiagnostics > Imaging > Reproductive Tract

Natural family planning

Davis MS, 1992 NAACOG's Clinical Issues in Perinatal and Women's Health Nursing

Natural family planning includes the calendar (rhythm), basal body temperature, ovulation (mucus), and sympto-thermal methods. Reliability of such methods often is underestimated, but effectiveness of...

Fertility Awareness > Methods > OverviewFertility Awareness > Effectiveness > Method ComparisonBody Literacy > Fertility Signs > Multiple Indicators

Clinical importance of endometrial histology and progesterone level assessment in luteal-phase defect

Kusuhara K, 1992 Hormone Research

In order to clarify the relationship between endometrial histology and progesterone (P4), plasma P4 and estradiol levels in the luteal phase were measured in 126 cases of unexplained infertility. Endo...

Infertility > Diagnosis > Luteal Phase DefectReproductive Endocrinology > Progesterone > Endometrial ResponseDiagnostics > Endometrial Biopsy > Luteal Phase Assessment

Effects of Ringer's lactate, Interceed(TC7) and Gore-Tex Surgical Membrane on postsurgical adhesion formation

Pagidas K et al., 1992 Fertility and Sterility

OBJECTIVE: To evaluate the effects of Ringer's lactate instillation, Interceed(TC7) (Johnson and Johnson Medical, Inc., New Brunswick NJ), and Gore-Tex Surgical Membrane (W. L. Gore and Associates, In...

Surgery > Adhesion Prevention > Barrier MaterialsSurgery > Adhesion Prevention > Ringer's LactateResearch Methodology > Animal Models > Adhesion Studies

Murine peritoneal injury and de novo adhesion formation caused by oxidized-regenerated cellulose (Interceed [TC7]) but not expanded polytetrafluoroethylene (Gore-Tex Surgical Membrane)

Haney AF et al., 1992 Fertility and Sterility

STUDY OBJECTIVE: To evaluate the impact of the materials contained in the available adhesion prevention barriers on the peritoneum. STUDY DESIGN, SETTING, PATIENTS: A murine paradigm was used, placi...

Surgery > Adhesion Prevention > Barrier MaterialsSurgery > Adhesion Prevention > Peritoneal BiologyResearch Methodology > Animal Models > Peritoneal Injury

Comparison of various therapies for the luteinized unruptured follicle syndrome

Check JH et al., 1992 International Journal of Fertility

A study was initiated to evaluate the prevalence of the luteinized unruptured follicle (LUF) syndrome in a group of 355 women with infertility. The diagnosis was established by carefully observing dai...

Infertility > Ovulatory Dysfunction > Luteinized Unruptured FollicleInfertility > Ovulation Induction > Gonadotropin TherapyDiagnostics > Ultrasound > Follicular Monitoring

Salpingitis isthmica nodosa in infertility and ectopic pregnancy

Saraçoglu FO et al., 1992 Gynecologic and Obstetric Investigation

Excised tubal segments from 94 infertile women with tubal obstruction, with a mean infertility duration of 5.3 years, and 40 women with ectopic tubal pregnancy were studied histopathologically to eval...

Infertility > Tubal Factor > Salpingitis Isthmica NodosaGeneral OB/GYN > Ectopic Pregnancy > Tubal PathologyDiagnostics > Histopathology > Tubal Disease

Reproduction in the older gravida. A literature review

Newcomb WW et al., 1991 The Journal of Reproductive Medicine

Infertility, spontaneous abortions and trisomic anomalies increase with maternal age, as do ectopic pregnancy, low birth weight, macrosomia, abruptio placentae and labor dysfunction. However, those ph...

Pregnancy > Maternal Health > Advanced Maternal AgePregnancy > Complications > Hypertension and DiabetesInfertility > Risk Factors > Maternal Age

Increased estradiol concentration of unknown origin

Vasiliades J et al., 1991 Clinical Chemistry

We report an interesting case of above-normal serum estradiol concentration of unknown origin. A 30-year-old white woman was seen for infertility problems. Hormonal evaluation revealed the following r...

Infertility > Diagnostics > Hormonal EvaluationReproductive Endocrinology > Estrogen > Elevated EstradiolNaProTECHNOLOGY > Hormone Assessment > Estradiol Monitoring

Evaluation of adhesion formation after laparoscopic treatment of polycystic ovarian disease

Kişnişçi H et al., 1991 Fertility and Sterility

The incidence and fertility effects of postoperative adhesion formation after laparoscopic ovarian electrocautery or laser photocoagulation of polycystic ovaries has not been adequately analyzed. Shor...

Surgery > Laparoscopic > Ovarian DrillingPCOS > Surgical Treatment > Adhesion FormationInfertility > Surgical Treatment > Postoperative Outcomes

Absorption of micronized progesterone from a nonliquefying vaginal cream

Kimzey LM et al., 1991 Fertility and Sterility

An improved delivery method to achieve sustained physiological P levels would be useful. Based on this single-dose pharmacokinetic study, micronized P prepared in a nonliquefying vaginal cream holds p...

Reproductive Endocrinology > Progesterone > Vaginal AdministrationRRM Methods > Progesterone Support > Delivery MethodsResearch Methodology > Pharmacokinetics > Hormone Delivery

Ultrasound surveillance of the cervix in twin gestations: management of cervical incompetency

Michaels WH et al., 1991 Obstetrics and Gynecology

Fifty-one consecutive twin pregnancies studied prospectively were compared with 153 consecutive control twin gestations that were concurrently delivered, but chosen retrospectively. Study patients wer...

Pregnancy > Complications > Cervical IncompetencePregnancy > Multiple Gestation > Twin Pregnancy ManagementDiagnostics > Ultrasound > Cervical Length Assessment

Histology of proximal tubal obstruction in cases of unsuccessful tubal canalization

Letterie GS et al., 1991 Fertility and Sterility

OBJECTIVE: To determine possible etiologies of unsuccessful fluoroscopically guided tubal canalization, we studied the histology of tubal segments in cases of failed canalization for proximal tubal ob...

Surgery > Tubal Surgery > Proximal Tubal ObstructionInfertility > Tubal Factor > HistopathologyDiagnostics > Imaging > Fluoroscopic Tubal Canalization

Polycystic ovaries and the risk of breast cancer

Gammon MD et al., 1991 American Journal of Epidemiology

Data from a case-control study that was conducted between 1980 and 1982 were analyzed to investigate the possible association between polycystic ovaries and the risk of breast cancer. The multicenter,...

PCOS > Comorbidities > Cancer RiskGeneral OB/GYN > Breast Health > Cancer Risk FactorsResearch Methodology > Epidemiology > Case-Control Study

Multicenter randomized clinical trial of home uterine activity monitoring for detection of preterm labor

Mou SM et al., 1991 American Journal of Obstetrics and Gynecology

Home uterine activity monitoring has been described as an effective means of detecting uterine contractions, but controversy exists whether it is home uterine activity monitoring or increased nursing ...

Pregnancy > Preterm Labor > Home MonitoringPregnancy > Complications > Preterm Birth PreventionResearch Methodology > Clinical Trials > Randomized Multicenter

Subfertility and the risk of low birth weight

Williams MA et al., 1991 Fertility and Sterility

OBJECTIVE: We evaluated the association between subfertility and low birth weight infants. DESIGN: Women in this analysis participated in a cross-sectional investigation of maternal risk factors for ...

Infertility > Outcomes > Pregnancy ComplicationsPregnancy > Fetal Development > Low Birth WeightResearch Methodology > Epidemiology > Cross-Sectional Study

Pathophysiology of polycystic ovarian disease: new insights

Insler V et al., 1991 Human Reproduction (Oxford, England)

The incidence of polycystic ovarian disease (PCOD) varies from 0.6 to 92%, depending on the parameters analysed, PCOD has been reported to appear in association with Cushing's Syndrome, adrenal hyperp...

PCOS > Pathophysiology > Multifactorial MechanismsReproductive Endocrinology > Insulin Resistance > PCOSPCOS > Comorbidities > Long-term Health Risks

Effect of opiate receptor blockade on the insulin response to oral glucose load in polycystic ovarian disease

Lanzone A et al., 1991 Human Reproduction (Oxford, England)

In order to test the hypothesis that endogenous opiates are at least partially responsible for hyperinsulinaemia in patients with polycystic ovarian disease (PCOD), the effect of naloxone (an opiate r...

PCOS > Metabolic Dysfunction > HyperinsulinemiaPCOS > Pathophysiology > Opioid System InvolvementReproductive Endocrinology > Neuroendocrinology > Opioid Receptors

Fallopian tube catheterization and recanalization under ultrasonic observation: a simplified technique to evaluate tubal patency and open proximally obstructed tubes

Lisse K et al., 1991 Fertility and Sterility

OBJECTIVE: To test a sonoscopic technique developed for transvaginal catheterization and recanalization of the fallopian tube. DESIGN: In a feasibility study, catheterization was performed with the u...

Surgery > Tubal Surgery > Tubal RecanalizationInfertility > Tubal Factor > Proximal Tubal ObstructionDiagnostics > Imaging > Ultrasound Tubal Assessment

Error in histologic dating of secretory endometrium: variance component analysis

Gibson M et al., 1991 Fertility and Sterility

OBJECTIVE: To characterize the extent and sources of imprecision in histologic dating of the endometrial biopsy. DESIGN: Duplicate endometrial biopsies from 25 women were dated by five evaluators on ...

Menstrual Cycle > Luteal Phase > Luteal Phase Defect DiagnosisDiagnostics > Histology > Endometrial Biopsy AccuracyResearch Methodology > Measurement Error > Observer Variability

High-resolution endovaginal ultrasonography of the endometrium: a noninvasive test for endometrial adequacy

Grunfeld L et al., 1991 Obstetrics and Gynecology

Endovaginal sonography of the endometrium demonstrates characteristic findings throughout the menstrual cycle. To correlate these findings with histologic criteria for normal endometrial development, ...

Diagnostics > Imaging > Endometrial UltrasoundReproductive Endocrinology > Endometrial Development > Secretory Phase AssessmentMenstrual Cycle > Luteal Phase > Endometrial Adequacy

The use of micronized progesterone in the treatment of menace of preterm delivery

Noblot G et al., 1991 European Journal of Obstetrics, Gynecology, and Reproductive Biology

The results of a study concerning the treatment of acute menace of preterm labor are given: beta-mimetics were administered intravenously in all cases (44) and micronized progesterone or placebo was a...

Pregnancy > Preterm Labor > Progesterone TreatmentPregnancy > Tocolysis > Adjunctive Progesterone TherapyReproductive Endocrinology > Progesterone > Micronized Progesterone Administration

Progesterone administration by nasal spray

Cicinelli E et al., 1991 Fertility and Sterility

The bioavailability and the clinical usefulness of the P administered by nasal spray were investigated. Ten healthy menopausal women received an IN spray administration (4 doses of an oleic P solution...

Reproductive Endocrinology > Progesterone > Alternative Delivery MethodsPerimenopause/Menopause > Hormone Therapy > Progesterone AdministrationReproductive Endocrinology > Pharmacokinetics > Progesterone Bioavailability

Women with endometriosis show a defect in natural killer activity resulting in a decreased cytotoxicity to autologous endometrium

Oosterlynck DJ et al., 1991 Fertility and Sterility

OBJECTIVE: The role of natural killer (NK) cells in the decreased cellular immunity of women with endometriosis was investigated. DESIGN, SETTING, PATIENTS: Thirty-four women were investigated prosp...

Endometriosis > Pathophysiology > Immune DysfunctionEndometriosis > Immunology > Natural Killer Cell ActivityInfertility > Endometriosis-Related > Immune Mechanisms

Focal pelvic tenderness, pelvic pain and dysmenorrhea in endometriosis

Ripps BA et al., 1991 The Journal of Reproductive Medicine

A study was conducted to determine if the increased recognition of various forms of endometriosis might have increased the ability to correlate focal tenderness with lesions. The prospective study of ...

Endometriosis > Diagnosis > Physical Examination FindingsEndometriosis > Deep Infiltrating > Clinical CorrelationGeneral OB/GYN > Pelvic Pain > Endometriosis Assessment

Home monitoring of uterine contractility. Summary of a workshop sponsored by the National Institute of Child Health and Human Development and the Bureau of Maternal and Child Health and Resources Development, Bethesda, Maryland, March 29 and 30, 1989

Rhoads GG et al., 1991 American Journal of Obstetrics and Gynecology

At an interdisciplinary workshop on home monitoring of uterine activity, participants reviewed the basis of this technology and its use in the identification of women at high risk of preterm delivery ...

Pregnancy > Preterm Labor > Home Monitoring TechnologyDiagnostics > Monitoring > Uterine Activity AssessmentPregnancy > Preterm Birth Prevention > Screening Methods