Assisted Reproduction · Safety and Risks

Preterm delivery, low birthweight and small-for-gestational-age in liveborn singleton babies resulting from in-vitro fertilization

Doyle P, Beral V, Maconochie N

Published March 1992 Human Reproduction (Oxford, England), 7(3), 425-428
DOI 10.1093/oxfordjournals.humrep.a137663 PMID 1587953

Abstract

The Medical Research Council In-Vitro Fertilization (IVF) Register report on births resulting from assisted conception in Great Britain demonstrated a high incidence of preterm and low birthweight babies. This incidence remained high even when the analysis was restricted to singleton babies. The present paper investigates possible risk factors for prematurity, low birthweight and small-for-gestational-age (SGA) in singleton IVF births. Thirteen per cent of singleton IVF babies were preterm, 11% low birthweight and 17% small-for-gestational-age. Analysis by multiple regression indicated that hypertension during pregnancy was an independent risk for preterm delivery, low birthweight and SGA, bleeding during pregnancy for preterm delivery, and the number of embryos transferred and the type of infertility for low birthweight.

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Assisted Reproduction › Safety and Risks › Neonatal and Birth Outcomes · Pregnancy › Neonatal Outcomes › Birth Weight · Birth and Delivery › Birth Outcomes › Maternal Morbidity
Pat Doyle, Valerie Beral, Noreen Maconochie
Patricia Doyle, Patrick Doyle, P Doyle, V Beral, N Maconochie
PMID 1587953 1587953 DOI 10.1093/oxfordjournals.humrep.a137663 10.1093/oxfordjournals.humrep.a137663 Doyle et al. 1992, Doyle 1992