To estimate the prevalence of diagnosed endometriosis (DE) in women in the United States and assess the associated symptomatic burden.
Methods
An online, cross-sectional survey of women aged 18-49 years was conducted from August 6, 2012, through November 14, 2012. Survey data (weighted by age, race, education, income, geographical distribution, and propensity score) were used to estimate the prevalence and symptomatic burden of DE in women in the United States. Weighted logistic regressions were used to assess differences in symptom burden between women with and without endometriosis.
Results
The prevalence of DE was estimated at 6.1% (2,922 of 48,020 women surveyed); 52.7% of women were 18-29 years of age when they were diagnosed with endometriosis. Most (86.2%) women experienced symptoms before diagnosis. More women with (vs. without) DE had menstrual pelvic pain/cramping (52.7 vs. 45.2%), non-menstrual pelvic pain/cramping (36.7 vs. 14.3%), infertility (11.6 vs. 3.4%), and dyspareunia (29.5 vs. 13.4%). Women with endometriosis were also more likely to report severe symptoms (OR (95% CI) 2.7 (2.3-3.1) for menstrual pelvic pain/cramping, 2.2 (1.7-2.9) for non-menstrual pelvic pain/cramping, and 2.4 (1.8-3.2) for dyspareunia).
Conclusion
The prevalence of DE among US women is notable, and affected women experience a substantial symptom burden.
endometriosis prevalence United States cross-sectional survey, diagnosed endometriosis symptomatic burden US women, endometriosis epidemiology pelvic pain dyspareunia infertility, endometriosis prevalence 6 percent women reproductive age, menstrual pelvic pain cramping endometriosis severity, endometriosis age at diagnosis symptom onset, non-menstrual pelvic pain endometriosis population survey, Fuldeore Soliman endometriosis national estimates, endometriosis symptom burden weighted logistic regression, endometriosis dyspareunia infertility odds ratio
DOI 10.1159/000452660 10.1159/000452660
Cite this article
Fuldeore, M. J., & Soliman, A. M. (2017). Prevalence and Symptomatic Burden of Diagnosed Endometriosis in the United States: National Estimates from a Cross-Sectional Survey of 59,411 Women. Gynecologic and obstetric investigation, 82(5), 453-461. https://doi.org/10.1159/000452660
Fuldeore MJ, Soliman AM. Prevalence and Symptomatic Burden of Diagnosed Endometriosis in the United States: National Estimates from a Cross-Sectional Survey of 59,411 Women. Gynecol Obstet Invest. 2017;82(5):453-461. doi:10.1159/000452660
Fuldeore, Mahesh J., and Ahmed M. Soliman. "Prevalence and Symptomatic Burden of Diagnosed Endometriosis in the United States: National Estimates from a Cross-Sectional Survey of 59,411 Women." Gynecologic and obstetric investigation, vol. 82, no. 5, 2017, pp. 453-461.
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