Academia Mental Health and Well-Being, 2025
Abstract
Background
Polycystic ovary syndrome (PCOS) is a common, chronic gynaecological condition impacting women of reproductive age. Women with PCOS have hormonal, ovulatory, and metabolic dysfunction resulting in multiple symptoms. The correlation between hormonal disbalance and mental health outcomes in PCOS across Black Asian Minority Ethnic populations was investigated in this systematic review and meta-analysis. The review included 30 studies and data from nearly 4,000 women with PCOS. Major depressive disorder affected 17% of patients with PCOS, with a range from 0% to 67%. Black, Asian, and other underserved populations were found to have higher prevalence of mental health disorders exacerbated by PCOS.