Chapter 33: Osteoporosis and Role of CrMS

Hilgers TW

Bone Health Osteoporosis

Chapter 33: Osteoporosis and Role of CrMS

Hilgers TW

The Medical and Surgical Practice of NaProTECHNOLOGY, 407-412, 2004

RRM Academy Synopsis

Low luteal estradiol linked to low bone density before menopause

Women with lower luteal estradiol had lower spine and femoral neck bone density in a pilot study of patients evaluated for infertility. Lower CrMS chart scores also went with lower hip bone density in these women.

Key Findings

Among patients evaluated for infertility, lower luteal-phase estradiol matched significantly lower spine and femoral neck bone density. Lower androstenedione matched lower spine density; lower DHEAS, lower femoral neck and total hip density.
In this group of patients, post-Peak progesterone, FSH, LH, total testosterone and free testosterone showed no statistically significant link with bone density. Post-Peak progesterone levels were normal.
Lower mucus cycle scores (17 women, against 23) matched significantly lower hip bone density. Lower menstrual scores (16 women, against 28) matched lower femoral neck and total hip density.
In a small group of postmenopausal patients given triestrogen and progesterone, spine and femoral neck bone density rose significantly from before treatment to after.

RRM Context

A 1990 review cited in the chapter named progesterone a bone hormone. It called the normal cycle a bone-building cycle. The chapter also cites studies linking low bone density to Depo-Provera shots and to past birth control pill use. Both are suppressive medications that can stop ovulation. The pilot ties CrMS mucus and period scores, markers of a normal cycle, to hip bone density. The findings support larger studies of normal cycles and bone health.

Our editorial summary of this paper, not the article's abstract.

Abstract

This chapter reviews the definition, risk factors, diagnosis by dual-energy x-ray absorptiometry (DXA) and drug treatment of osteoporosis. The chapter cites studies reporting decreased bone mineral density (BMD) with the use of Depo-Provera and lower BMD in premenopausal women who had used oral contraceptives. Hilgers reports a Pope Paul VI Institute study of women with infertility in which a decreased post-Peak estradiol sum, lower androstenedione and DHEA levels, and lower CrMS mucus cycle and menstrual scores were associated with lower bone density, while post-Peak progesterone levels were normal. The chapter describes these findings as preliminary and pilot in orientation, reports improved spine and femoral neck density in a small group of postmenopausal women given triestrogen and progesterone, and states that more research is needed.

Topics

Bone Health › Osteoporosis › Diagnosis and Treatment · Reproductive Endocrinology › Ovarian Hormones › Estrogen · Menstrual Cycle › Cycle Disorders › Ovulatory Disturbances

Thomas W Hilgers

Tom Hilgers, T Hilgers

Hilgers et al. 2004, Hilgers 2004

Chapter 33: Osteoporosis and Role of CrMS

Low luteal estradiol linked to low bone density before menopause

Key Findings

RRM Context

Abstract

Topics

By this author

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