Hypotensive action of progesterone in experimental and human hypertension

Armstrong JG

doi:10.3181/00379727-102-25282

Therapeutics · Hormonal Agents

Hypotensive action of progesterone in experimental and human hypertension

Armstrong JG

Published November 1959 Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 102(2), 452-455

DOI 10.3181/00379727-102-25282 PMID 13794314

Abstract

Summary(1) Progesterone administration to rats and dogs with experimental hypertension and to humans with primary arterial hypertension resulted in a decline in blood pressure levels. Blood pressures increased once more in all cases after progesterone was discontinued. (2) In humans, but not necessarily in rats and dogs, blood pressure reduction would appear to have resulted from natruresis.

Topics

Therapeutics Hormonal Agents Progesterone and Progestins

Therapeutics › Hormonal Agents › Progesterone and Progestins

PMID 13794314 13794314 DOI 10.3181/00379727-102-25282 10.3181/00379727-102-25282 Armstrong et al. 1959, Armstrong 1959

Keywords

Antihypertensive Agents, Hypertension, Hypotension, Progesterone/pharmacology, Antihypertensive Agents, Progesterone, ANTIHYPERTENSIVE AGENTS, PROGESTERONE/pharmacology

Hypotensive action of progesterone in experimental and human hypertension

Abstract

Topics

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