The irregular menses experienced by obese and/or hirsute women were studied by daily measurement of serum LH, FSH, estradiol (E2) and progesterone (P). During 8 cycles of 24 to 157 days, each episode of menstrual bleeding was preceded by hormonal evidence of follicular maturation and corpus luteum formation. The premenstrual fluctuations of LH and E2 were not different from those observed in normal cycles. Although the luteal phase was of more than 10 days' duration, progesterone secretion was subnormal during each cycle. Serum FSH was low throughout the time preceding the LH/FSH surge. These data suggest that inadequate corpus luteum progesterone secretion may be characteristic of the menstrual cycles in oligomenorrheic, obese infertile women.
PMID 4835128 4835128 DOI 10.1210/jcem-39-1-145 10.1210/jcem-39-1-145
Cite this article
Sherman, B. M., & Korenman, S. G. (1974). Measurement of serum LH, FSH, estradiol and progesterone in disorders of the human menstrual cycle: the inadequate luteal phase. *The Journal of clinical endocrinology and metabolism*, *39*(1), 145-149. https://doi.org/10.1210/jcem-39-1-145
Sherman BM, Korenman SG. Measurement of serum LH, FSH, estradiol and progesterone in disorders of the human menstrual cycle: the inadequate luteal phase. J Clin Endocrinol Metab. 1974;39(1):145-149. doi:10.1210/jcem-39-1-145
Sherman, Barry M., and Stanley G. Korenman. "Measurement of serum LH, FSH, estradiol and progesterone in disorders of the human menstrual cycle: the inadequate luteal phase." *The Journal of clinical endocrinology and metabolism*, vol. 39, no. 1, 1974, pp. 145-149.
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