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The Prevalence of Polycystic Ovary Syndrome: A Brief Systematic Review

Deswal R et al., 2021 Open Access Journal of Human Reproductive Sciences

Background: Polycystic ovary syndrome (PCOS), the major endocrinopathy among reproductive-aged women, is not yet perceived as an important health problem in the world. It affects 4%-20% of women of re...

PCOSReproductive Endocrinology

The Menstrual Disturbances in Endocrine Disorders: A Narrative Review

Saei Ghare Naz M et al., 2021 Open Access International Journal of Endocrinology and Metabolism

Context: Menstrual cycle is considered the fifth vital sign among women. This study aimed to summarize the menstrual disturbances in different endocrine disorders. Evidence Acquisition: In this narrat...

Reproductive EndocrinologyMenstrual CycleDiagnostics

"Biophysical effects, safety and efficacy of raspberry leaf use in pregnancy: a systematic integrative review"

Bowman R et al., 2021 Open Access BMC Complementary Medicine and Therapies

Background: Childbearing women have been using various herbs to assist with pregnancy, labour and birth for centuries. One of the most common is raspberry leaf. The evidence base for the use of raspbe...

Pregnancy > Complementary Therapies > Herbal MedicineGeneral OB/GYN > Labour and Birth > Natural InterventionsResearch Methodology > Systematic Reviews > Integrative Review

Natural Cycles app: contraceptive outcomes and demographic analysis of UK users

Pearson JT et al., 2021 The European Journal of Contraception & Reproductive Health Care : the Official Journal of the European Society of Contraception

Purpose: Digital fertility awareness-based contraception offers an alternative choice for women who do not wish to use hormonal or invasive methods. The aim of this study was to investigate the key de...

Fertility Awareness > Digital Tools > Natural Cycles AppContraception/Comparison > Fertility Awareness Methods > Effectiveness StudiesFertility Awareness > Contraceptive Use > Prospective Cohort Studies

A Clinical Approach to Catamenial Epilepsy: A Review

Frank S et al., 2021 The Permanente Journal

Importance: Catamenial epilepsy (CE) is exacerbated by hormonal fluctuations during the menstrual cycle. Approximately 1.7 million women have epilepsy in the United States. CE affects more than 40% of...

Reproductive EndocrinologyMenstrual Cycle

Photobiomodulation: The Clinical Applications of Low-Level Light Therapy

Glass GE, 2021 Aesthetic Surgery Journal

Background: Low-level light therapy (LLLT) is a recent addition to the pantheon of light-based therapeutic interventions. The absorption of red/near-infrared light energy, a process termed "photobiomo...

Diagnostics > Therapeutic Technologies > PhotobiomodulationResearch Methodology > Clinical Evidence Review > Light-Based Therapy

Effects of three contraceptive methods on depression and sexual function: An ancillary study of the ECHO randomized trial

Singata-Madliki M et al., 2021 Open Access International Journal of Gynaecology and Obstetrics: the Official Organ of the International Federation of Gynaecology and Obstetrics

Objective: To compare the effects of depot medroxyprogesterone acetate (DMPA-IM), levonorgestrel (LNG) implant, and copper intrauterine device (IUD) on mood and sexual function. Methods: At the Effec...

Contraception/ComparisonReproductive Endocrinology

Simulated effects of early menopausal bone mineral density preservation on long-term fracture risk: a feasibility study

E O Billington et al., 2021 Osteoporos Int

Prevention of early menopausal bone loss may reduce the future burden of osteoporosis. In this modelling exercise, an osteoporosis prevention strategy involving 5-year infusions of zoledronic acid, be...

Bone Health > Osteoporosis Prevention > Menopausal Bone LossPerimenopause/Menopause > Bone Health > Fracture Risk ReductionBone Health > Pharmacological Interventions > Bisphosphonates

Post-caesarean Niche (Isthmocele) in Uterine Scar: An Update

Kulshrestha V et al., 2021 Journal of Obstetrics and Gynaecology of India

Uterine niche is one of the emerging complications of caesarean section. With rising caesarean rates, the caesarean-related iatrogenic complications are also on the rise. These include placenta accret...

SurgeryGeneral OB/GYN

Multiple Births in Fertility Treatment 2019

Human Fertilisation and Embryology Authority, 2021

# Multiple births in fertility treatment 2019 UK multiple birth statistics for IVF and DI fertility treatment Published: February 2022 [Download the underlying dataset as Excel Worksheet](https://www....

Infertility > ART Outcomes > Multiple BirthsInfertility > IVF > Embryo Transfer PolicyResearch Methodology > Population Statistics > Fertility Treatment Outcomes

Impact of COVID-19 on Fertility Treatment 2020

Human Fertilisation and Embryology Authority, 2021

# Impact of COVID-19 on fertility treatment 2020 UK statistics for IVF and DI treatment, storage and donation Published: May 2022 [Download the underlying dataset as Excel Worksheet](https://www.hfea....

Infertility > ART Access > COVID-19 ImpactInfertility > IVF > Treatment Trends and StatisticsResearch Methodology > Population Statistics > Pandemic Effects on Fertility Services

Naprotechnologia – szansa na potomstwo czy oszustwo?

Kandzia T, 2021 Sympozjum

NaProTECHNOLOGY – a chance for offspring or fraud? In the media space in Poland, you can meet the concept of Naprotechnology as an alternative to the in vitro procedure. Often, many myths and untruths...

NaProTECHNOLOGY > Overview > Effectiveness and EthicsInfertility > Restorative Reproductive Medicine > NaProTECHNOLOGYRRM Methods > Creighton Model > Diagnostic Applications

"Phase II 6-month Cyclic Progesterone/Spironolactone pilot Therapy Trial in Polycystic Ovary Syndrome : pre-post, single-arm feasibility study"

Prior JC et al., 2021 Open Collections

Androgenic Polycystic Ovary Syndrome (PCOS) creates physical/emotional burdens in 4-20% of premenopausal women living with PCOS (WLWP) including: few menstruations per year, subfertility, hirsutism/ac...

PCOS > Treatment > Progesterone TherapyPCOS > Treatment > Anti-Androgen TherapyResearch Methodology > Study Design > Feasibility and Pilot Studies

Contraceptive Effectiveness of an FDA-Cleared Birth Control App: Results from the Natural Cycles U.S. Cohort

Pearson JT et al., 2020 Journal of Women's Health (2002)

Background: Digital fertility awareness-based methods of birth control are an attractive alternative to hormonal or invasive birth control for modern women. They are also popular among women who may b...

Fertility Awareness > Digital Tools > App-Based MethodsContraception/Comparison > Effectiveness Studies > Fertility Awareness MethodsResearch Methodology > Study Design > Prospective Cohort Study

Postoperative Ultrasound as a Predictor of Newborn Function and Ambulation after Open Fetal Myelomeningocele Repair

Buskmiller C et al., 2020 Fetal Diagnosis and Therapy

Objective: Function of the lower extremities after prenatal myelomeningocele (MMC) repair is best assessed with ambulatory function at 30-36 months of age, but parents often ask about function before ...

Pregnancy > Fetal Surgery > Myelomeningocele RepairPregnancy > Prenatal Diagnosis > Ultrasound AssessmentGeneral OB/GYN > Neonatal Outcomes > Neurodevelopmental Follow-up

Pregnancy-induced long-term uterine vascular remodeling in the rat

Camilleri C et al., 2020 Reproductive Biology

Despite the available research investigating uterine physiology during and immediately following pregnancy, including at the vascular and muscular levels, knowledge of the potential long-term timeline...

Pregnancy > Maternal Physiology > Uterine Vascular AdaptationPostpartum > Uterine Recovery > Vascular RemodelingResearch Methodology > Animal Models > Reproductive Physiology

Myo-inositol supplementation to prevent gestational diabetes in overweight non-obese women: bioelectrical impedance analysis, metabolic aspects, obstetric and neonatal outcomes - a randomized and open-label, placebo-controlled clinical trial

Vitale SG et al., 2020 International Journal of Food Sciences and Nutrition

This study aims to evaluate the effects of myo-inositol supplementation on gestational diabetes mellitus (GDM) rates and body water distribution in overweight non-obese women. 223 overweight non-obese...

Pregnancy > Gestational Diabetes > Prevention StrategiesPregnancy > Nutritional Supplementation > Myo-InositolPregnancy > Complications > Pregnancy-Induced Hypertension

Marital Satisfaction of Infertile Couples Using Natural Procreative Technology (NaProTECHNOLOGY)

Konicki AJ et al., 2020 Journal of Christian Nursing : a Quarterly Publication of Nurses Christian Fellowship

Infertility affects one in 16 married women in the United States where 12.7% of these seek treatment. The stress of infertility and treatment is known to impact marital satisfaction, which can be furt...

NaProTECHNOLOGY > Patient Outcomes > Psychosocial WellbeingInfertility > Psychosocial Aspects > Marital SatisfactionEthics/Philosophy > Religious Perspectives > Reproductive Technology

Is ART utilization the best indicator of access to fertility care?

Stanford JB et al., 2020 Reproductive Biomedicine Online

While we agree with many of the points stated by Dyer et al. in their recent commentary inRBMO(Dyer et al., 2020), we believe their conclusions are focused too narrowly. Limiting the indicator of acce...

Infertility > Treatment Access > Non-ART ApproachesInfertility > Policy > Registry DevelopmentRRM Methods > Advocacy > Alternative Fertility Treatment Frameworks

State of the Fertility Sector 2019/2020

Human Fertilisation and Embryology Authority, 2020

# State of the fertility sector 2019/2020 **Annual publication on our regulatory work** Published: November 2020 [**Download the underlying data set as.xlsx (47KB)**](https://www.hfea.gov.uk/media/328...

General OB/GYN > Fertility Regulation > UK Regulatory FrameworkGeneral OB/GYN > Healthcare Policy > Fertility Sector Oversight

Current use of combined hormonal contraception is associated with glucose metabolism disorders in perimenopausal women

Mosorin ME et al., 2020 European Journal of Endocrinology

Objective: The use of combined hormonal contraceptives (CHCs) worsens glucose tolerance, but the risk for glucose metabolism disorders remains controversial. Design: The study is a prospective longitu...

Perimenopause/Menopause > Hormonal Contraception > Metabolic RisksContraception/Comparison > Side Effects > Glucose Metabolism DisordersReproductive Endocrinology > Metabolic Health > Diabetes Risk

Oral contraceptive use and risk of suicidal behavior among young women

Edwards AC et al., 2020 Psychological Medicine

Background: Oral contraceptive use has been previously associated with an increased risk of suicidal behavior in some, but not all, samples. The use of large, representative, longitudinally-assessed s...

Contraception/ComparisonEthics/Philosophy

Supplementation of dehydroepiandrosterone (DHEA) in pre- and postmenopausal women - position statement of expert panel of Polish Menopause and Andropause Society

Rabijewski M et al., 2020 Open Access Ginekologia Polska

Dehydroepiandrosterone (DHEA) concentration decreases with age, therefore, DHEA has been considered a hormone that reduces the symptoms associated with aging, so the usefulness of DHEA in premenopausa...

Perimenopause/Menopause > Hormone Therapy > DHEA SupplementationBone Health > Osteoporosis > Hormonal TreatmentReproductive Endocrinology > Adrenal Hormones > Dehydroepiandrosterone

Differences in fracture prevalence and in bone mineral density between Chinese and White Canadians: the Canadian Multicentre Osteoporosis Study (CaMos)

S N Morin et al., 2020 Arch Osteoporos

Fracture determinants differ between Canadians of Chinese and White descent, the former constituting the second largest visible minority group in Canada. The results of this study support the importan...

Bone Health > Osteoporosis > Ethnic Differences in Bone DensityReproductive Endocrinology > Bone Metabolism > Population-Based StudiesResearch Methodology > Cohort Studies > Multicentre Observational

Do fertility tracking applications offer women useful information about their fertile window?

Ali R et al., 2020 Open Access Reproductive Biomedicine Online

RESEARCH Question: To characterize mobile fertility tracking applications (apps) to determine the use of such apps for women trying to conceive by identifying the fertile window. Design: An explorator...

Fertility Awareness > Technology > Mobile ApplicationsFertility Awareness > Methods > Fertile Window IdentificationInfertility > Conception Optimization > Digital Tools

Antioxidants for female subfertility

Showell MG et al., 2020 The Cochrane Database of Systematic Reviews

EDITORIAL NOTE: M.G. Showell, R. Mackenzie‐Proctor, V. Jordan, and R.J. Hart, “Antioxidants for Female Subfertility,” Cochrane Database of Systematic Reviews, no. 8 (2020): CD007807, https://doi.org/1...

InfertilityReproductive Endocrinology

Peri-implantation intercourse does not lower fecundability

Hansen JL et al., 2020 Human Reproduction (Oxford, England)

STUDY QUESTION: Does sexual intercourse in the implantation time window (5-9 days after ovulation) reduce fecundability? SUMMARY ANSWER: After adjustment for intercourse in the fecund window and clus...

Fertility AwarenessInfertility

Vertebral Fractures: Which Radiological Criteria Are Better Associated With the Clinical Course of Osteoporosis?

Brian C Lentle et al., 2021 Can Assoc Radiol J

Study purposeMorphometric methods categorize potential osteoporotic vertebral fractures (OVF) on the basis of loss of vertebral height. A particular example is the widely used semiquantitative morphom...

Bone Health > Fractures > Vertebral Fracture AssessmentDiagnostics > Radiology > Vertebral Fracture ClassificationResearch Methodology > Longitudinal Studies > Fracture Epidemiology

A program to estimate insulin resistance based on data from the oral glucose tolerance test

Contreras PH et al., 2020 Open Access Revista Medica De Chile

Background An instrument to help clinicians to evaluate the oral glucose tolerance test (OGTT) at-a-glance is lacking.

Diagnostics > Metabolic Assessment > Insulin Resistance EstimationReproductive Endocrinology > Metabolic Disorders > Glucose Tolerance TestingResearch Methodology > Clinical Tools > Diagnostic Software