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Effects of menstrual disorders and dysmenorrhea on cardiovascular disease: a Mendelian randomization study
BACKGROUND: Observational studies have demonstrated associations between menstrual disorders, dysmenorrhea, and cardiovascular disease (CVD). However, it remains unclear whether these associations are...
Photobiomodulation therapy at 632 nm wavelength ameliorates intrauterine adhesion via activation of cAMP/PKA/CREB pathway
Intrauterine adhesion (IUA), a major cause of uterine infertility, is pathologically characterized by endometrial fibrosis. Current treatments for IUA have poor efficacy with high recurrence rate, and...
PCOS stratification for precision diagnostics and treatment
Globally, polycystic ovarian syndrome (PCOS) affects approximately 10% of fertile women, leading to great health and economic burden. PCOS is a heterogenous illness that can cause infertility, irregul...
Hormonal contraceptive use is associated with differences in women's inflammatory and psychological reactivity to an acute social stressor
Women using hormonal contraceptives (HCs) exhibit numerous signs of chronic inflammation, including elevated C-reactive protein levels and greater risk of developing mood and autoimmune disorders. How...
New insights about endometriosis-associated ovarian cancer: pathogenesis, risk factors, prediction and diagnosis and treatment
Previous studies have shown that the risk of malignant transformation of endometriosis in premenopausal women is approximately 1%, significantly impacting the overall well-being and quality of life of...
Assisted reproductive technology in Japan: A summary report for 2022 by the Ethics Committee of the Japan Society of Obstetrics and Gynecology
Annual summary report on assisted reproductive technology (ART) cycles performed in Japan during 2022, published by the Ethics Committee of the Japan Society of Obstetrics and Gynecology (JSOG). Repor...
CARTR Plus 2024 Annual Report (2023 Data) - Canadian Assisted Reproductive Technologies Register
CARTR Plus 2024 annual report covering Canadian ART activity for treatment cycles completed in 2023. Reports cycles performed, single-embryo transfer rates, clinical pregnancy and live-birth rates, AR...
Sensitization to textile dyes in Spain: Epidemiological situation (2019-2022)
AbstractBackgroundCurrent frequency and features for positivity to textile dye mix (TDM) in Spain are unknown.ObjectivesTo study the frequency, clinical features and simultaneous positivity between TD...
Effects of long and short ejaculatory abstinence on sperm parameters: a meta-analysis of randomized-controlled trials
PURPOSE: This study aimed to investigate the effects of ejaculatory abstinence on sperm parameters. METHODS: Thirteen studies published between 2013 and 2022 were included in this meta-analysis. 2,315...
Serum Zinc Levels in Women with Polycystic Ovarian Syndrome are Lower as Compared to Those without Polycystic Ovarian Syndrome: A Cohort Study
BACKGROUND: Zinc is an essential micronutrient, a vital stabiliser and a cofactor in many enzymes such as superoxide dismutase and phospholipase C and also acts as an antioxidant by protecting the sul...
Assisted reproductive technology in Japan: A summary report for 2021 by the Ethics Committee of the Japan Society of Obstetrics and Gynecology
Annual summary report on assisted reproductive technology (ART) cycles performed in Japan during 2021, published by the Ethics Committee of the Japan Society of Obstetrics and Gynecology (JSOG). Repor...
Effect of environmental factors on seminal microbiome and impact on sperm quality
OBJECTIVE: This review provides a comprehensive overview of the existing research on the seminal microbiome and its association with male infertility, while also highlighting areas that warrant furthe...
Recurrent Miscarriage and RRM with NeoFertility: RCOG Guidelines Review and Case Report
Presentation covering three topics: (1) Review of RCOG Green-top Guideline No. 17 on Recurrent Miscarriage (Regan et al., BJOG 2023), (2) Key concepts of Restorative Reproductive Medicine with NeoFert...
Bisphenols in daily clothes from conventional and recycled material: evaluation of dermal exposure to potentially toxic substances
AbstractGiven the increasing concern about chemical exposure from textiles, our study examines the risks of dermal exposure to bisphenol A (BPA), bisphenol S (BPS), bisphenol B (BPB) and bisphenol F (...
Rapport annuel d'AMP Vigilance 2023
Rapport annuel d'AMP Vigilance 2023 de l'Agence de la biomédecine. ENGLISH SUMMARY: 2023 ART vigilance report from the French Agence de la biomédecine. AMP Vigilance is the mandatory adverse-event sur...
mHealth technologies for pregnancy prevention: A challenge for patient-centred contraceptive counselling in Dutch general practice
BACKGROUND: A general practitioner (GP) standardly provides contraceptive counselling and care in the Netherlands. Recent years have seen the rise of mobile health technologies that aim to prevent pre...
EuMAR stakeholder engagement: an analysis of medically assisted reproduction (MAR) data collection practices in EU countries†
Fraction of cancers attributable to and prevented by reproductive factors and exogenous hormones use in Italy
OBJECTIVE: Endogenous and exogenous hormonal factors have been associated with female breast, genital, and colorectal cancer risk. The aim of the present study is to conduct an evidence-based evaluati...
A systematic review of genome-wide analyses of methylation changes associated with assisted reproductive technologies in various tissues
IMPORTANCE: Because analytic technologies improve, increasing amounts of data on methylation differences between assisted reproductive technology (ART) and unassisted conceptions are available. Howeve...
Exposure assessment and risks associated with wearing silver nanoparticle-coated textiles
Background Silver (Ag) nanoparticles (NPs) are used increasingly in consumer and healthcare fabrics due to their antimicrobial properties. Abrasive leaching experiments have shown that AgNPs can be re...
DIR Jahrbuch 2023 (Deutsches IVF-Register Annual Report 2023)
DIR Jahrbuch 2023 des Deutschen IVF-Registers. ENGLISH SUMMARY: 2023 Annual Report of the German IVF Registry (Deutsches IVF-Register, DIR). Reports German ART cycle counts, treatment indications, emb...
Benefits of Resistance Training During Pregnancy for Maternal and Fetal Health: A Brief Overview
Research demonstrates resistance training is not only safe but also beneficial for pregnant women. However, exercise recommendations for pregnant women still minimize the importance of resistance exer...
Outcomes of fetal lower urinary tract obstruction based on timing of oligohydramnios onset
Objective: Fetal Lower Urinary Tract Obstruction (LUTO) is associated with oligohydramnios and significant fetal morbidity, resulting in poor lung development and perinatal death. However, oligohydram...
The Impact of Irregular Menstruation on Health: A Review of the Literature
Women are considered to have an irregular menstrual cycle if their cycle length is less than 21 days or more than 35 days, accompanied by less or very severe blood flow. The prevalence of menstrual cy...
Fertility after expanded polytetrafluoroethylene use after endometrioma cystectomy: a pilot study
Introduction: Pregnancy rates after the placement of expanded polytetrafluoroethylene (ePTFE, trade name Gore-Tex®) for adhesion prevention following cystectomy of endometriomas ≥3 cm and excision of ...
"There's no time limit on grief:" Women's perspectives on a novel reproductive grief screening tool
Objective: Women who have experienced reproductive loss (i.e., miscarriage, stillbirth, abortion) evaluated the usefulness of a novel screening tool, Reproductive Grief Screen (RGS), to identify patie...
Unveiling the Microfiber Release Footprint: Guiding Control Strategies in the Textile Production Industry
Microplastic fibers from textiles have been known to significantly contribute to marine microplastic pollution. However, little is known about the microfiber formation and discharge during textile pro...
Progestogen Hypersensitivity
Progestogen hypersensitivity (PH) is a heterogeneous disease characterized by diverse cutaneous manifestations, bronchospasm, and/or anaphylaxis. Possible triggers include ovarian progesterone and exo...
Pregnancy Outcomes after Uterus-sparing Operative Treatment for Adenomyosis: A Systematic Review and Meta-analysis
ART in Europe, 2019: results generated from European registries by ESHRE
**STUDY QUESTION:** What are the data and trends on ART and IUI cycle numbers and their outcomes, and on fertility preservation (FP) interventions, reported in 2019 as compared to previous years? **S...
Raman Microspectroscopy evidence of microplastics in human semen
The presence of microplastics (MPs) in human fluids and organs is a great concern, since, as highlighted by recent studies on animal models, they could cause alterations of several physiological funct...
Maternal Iron and Vitamin D Status during the Second Trimester Is Associated with Third Trimester Depression Symptoms among Pregnant Participants in the APrON Cohort
Background: The maternal status of multiple micronutrients during pregnancy and postpartum and their potential associations with maternal health outcomes are largely undescribed. Objectives: This stu...
Vaginal micronised progesterone for the prevention of hypertensive disorders of pregnancy: A systematic review and meta-analysis
Background: Treatment with vaginal progesterone reduces the risk of miscarriage and preterm birth in selected high-risk women. The hypothesis that vaginal progesterone can reduce the risk of hypertens...
State of the Fertility Sector 2022/2023
# State of the fertility sector 2022/23 Annual publication on HFEA licensed centres (1st April 2022 – 31st March 2023) Published: 12th September 2023 [Download the underlying dataset as .xlsx](https:/...
Per- and polyfluoroalkyl substances (PFAS) in consumer products: Current knowledge and research gaps
Occurrence and potential release of heavy metals in female underwear manufactured in China: Implication for women's health
Underwear is a potential source of women's exposure to heavy metals owing to its direct contact with the skin, especially the skin of the vagina and vulva, which has a strong absorptive capacity. Howe...
Prenatal Exposure to PFAS, Associations with Preterm Birth and Modification by Maternal Estrogen Levels: The Maoming Birth Study
BACKGROUND: Estrogens play a critical role in parturition, and poly- and perfluoroalkyl substances (PFAS), which have estrogenic effects, have been associated with preterm birth. However, the impact o...
Intraovarian Platelet-rich Plasma Administration Induced Spontaneous Ovulation in an Anovulatory Woman With PCOS
The use of platelet-rich plasma (PRP) has become popular as an adjunct to fertility treatment for women with infertility, particularly those with low ovarian reserve and premature ovarian insufficienc...
Endocrine disrupting chemicals and male fertility: from physiological to molecular effects
The deleterious effects of chemical or non-chemical endocrine disruptors (EDs) on male fertility potential is well documented but still not fully elucidated. For example, the detection of industrial c...
Repair of Isthmocele Following Embolization of Uterine Arteriovenous Malformation
Objective: To present a case of concurrent uterine arteriovenous malformation (AVM) and isthmocele, treated with ethylene vinyl alcohol copolymer (EVAC) embolization of the AVM followed by robotic ist...
Evidence-based guideline: unexplained infertility
Guideline Group on Unexplained Infertility; Romualdi D(1), Ata B(2)(3), Bhattacharya S(4), Bosch E(5), Costello M(6)(7), Gersak K(8), Homburg R(9), Mincheva M(10), Norman RJ(7)(11), Piltonen T(12), ...
Recommendations for reducing the risk of viral transmission during fertility treatment with the use of autologous gametes: a committee opinion
Sexually transmitted infections are of major concern to reproductive specialists. Heading the list are human immunodeficiency virus types 1 and 2 and hepatitis B and C viruses. These pathogens, which ...
Melatonin improves oxidative state and lactate metabolism in rodent Sertoli cells
Antioxidant actions of melatonin and its impact on testicular function and fertility have already been described. Considering that Sertoli cells contribute to provide structural support and nutrition ...
Molar Pregnancy with Co-Existing Viable Fetus Delivered Preterm at 24 Weeks Gestation: A Case Report
Maternal b-HCG levels fell to undetectable levels one month after birth without treatment. She was doing well and a follow-up six months later revealed no evidence of retained tissue or recurrence.
Assessment of urinary aromatic amines in Brazilian pregnant women and association with DNA damage: Influence of genetic diversity, lifestyle, and environmental and socioeconomic factors
Aromatic amines (AAs) are polar organic chemicals with a wide environmental distribution originating from various sources, such as tobacco smoke, diesel exhaust, and dermal absorption from textile pro...
Fetoscopic laser photocoagulation for complex heterokaryotypic monochorionic twin management
Data sharing not applicable - no new data generated
Case Reports from Women Using a Quantitative Hormone Monitor to Track the Perimenopause Transition
The fertility tracking of menstrual cycles during perimenopause with a quantitative hormone monitor is a novel undertaking. Women in regular menstrual cycles have been tracking their fertility using d...
Placental histology for targeted risk assessment of recurrent spontaneous preterm birth
Background: Spontaneous preterm birth significantly increases the risk for a recurrent preterm birth. Only a few identifiable clinical risk factors can be referenced in counseling for recurrent preter...
Effects of Low Vitamin C Intake on Fertility Parameters and Pregnancy Outcomes in Guinea Pigs
Identifying how specific nutrients can impact fertility, pregnancy, and neonatal outcomes will yield important insights into the biological mechanisms linking diet and reproductive health. Our study i...