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Endometriosis

McBean JH et al., 2019 Endocrine reviews

Pelvic endometriosis is a complex syndrome characterized by an estrogen-dependent chronic inflammatory process that affects primarily pelvic tissues, including the ovaries. It is caused when shed endo...

EndometriosisReproductive Endocrinology

Duration of Hormonal Contraception and Risk of Cervical Cancer

Kusmiyati Y et al., 2019 Open Access Kesmas: National Public Health Journal

The use of long hormonal contraceptives can disrupt the balance of estrogen in the body, resulting in abnormal cell changes. This study aimed to determine a correlation between the duration of hormona...

Contraception/Comparison > Hormonal Contraception > Cancer RiskGeneral OB/GYN > Cervical Health > Cervical Cancer Risk FactorsResearch Methodology > Study Design > Case-Control Studies

Fertility awareness based methods for pregnancy prevention

Urrutia RP et al., 2019 BMJ (Clinical Research Ed.)

### What you need to know Fertility awareness based methods of contraception are increasingly being used for pregnancy prevention.1 In the US, the proportion of contraceptive users who choose such met...

Fertility Awareness > Methods > EffectivenessFertility Awareness > Clinical Practice > Patient CounselingContraception/Comparison > Method Comparison > Fertility Awareness Methods

Could exotic mosquito-borne diseases emerge in Canada with climate change?

Ng V et al., 2019 Open Access Canada Communicable Disease Report = Releve Des Maladies Transmissibles Au Canada

Of the 3,500 species of mosquitoes worldwide, only a small portion carry and transmit the mosquito-borne diseases (MBDs) that cause approximately half a million deaths annually worldwide. The most com...

General OB/GYN

Relationship of maximum follicular size, age of woman, and reproductive implications in women attending fertility clinic in St. Margaret's Hospital, Lokoja, using Creighton Model FertilityCare™ System and NaProTECHNOLOGY

Achebe FU, 2019 The Nigerian Journal of General Practice

Background: Some authorities have found that, when the mean follicular diameter is >25 mm, the follicle is considered large, and these authorities are convinced that large follicles are biomarkers to ...

NaProTECHNOLOGY > Diagnostics > Follicular MonitoringInfertility > Diagnosis > Ovulation DefectsReproductive Endocrinology > Ovarian Function > Follicular Development

Short- and long-term effect of contraceptive methods on fecundity

Berglund Scherwitzl E et al., 2019 The European Journal of Contraception & Reproductive Health Care : the Official Journal of the European Society of Contraception

Objective: The aim of the study was to compare the effect of previously used contraceptive methods on women's shortand long-term fecundity. Use of hormonal contraception (HC) was compared with the use...

Contraception/ComparisonFertility Awareness

Adolescent combined hormonal contraceptives and surgical repair of anterior cruciate tears: a risky recommendation based on an unproven causal relationship

Jerilynn Prior et al., 2019 Phys Sportsmed

A recent cross-sectional national USA registry of surgery to repair anterior cruciate ligament tears found that fewer adolescent women who reported using combined hormonal contraceptives (CHC) had the...

Body Literacy > Education > Adolescent HealthContraception/Comparison > Side Effects > Musculoskeletal EffectsBone Health > Peak Bone Mass > Hormonal Contraception Impact

Isthmocele: an overview of diagnosis and treatment

Kremer TG et al., 2019 Open Access Revista Da Associacao Medica Brasileira (1992)

An isthmocele, a cesarean scar defect or uterine niche, is any indentation representing myometrial discontinuity or a triangular anechoic defect in the anterior uterine wall, with the base communicati...

Surgery > Uterine Surgery > Cesarean Scar Defect RepairDiagnostics > Imaging > Transvaginal UltrasoundGeneral OB/GYN > Cesarean Section Complications > Isthmocele

Caffeinated beverage intake and serum caffeine metabolites and risk of pregnancy loss

Purdue‐Smithe A et al., 2019 Open Access Current developments in nutrition

Objectives: The association between caffeine and pregnancy loss remains controversial due to limitations of prior studies such as relying on self-reported intake only, exposure measurement after clini...

Pregnancy > Pregnancy Loss > Modifiable Risk FactorsPregnancy > Preconception Health > Dietary ExposuresResearch Methodology > Study Design > Randomized Controlled Trial

Predictors of imminent non-vertebral fracture in elderly women with osteoporosis, low bone mass, or a history of fracture, based on data from the population-based Canadian Multicentre Osteoporosis Study (CaMos)

Jonathan D Adachi et al., 2019 Arch Osteoporos

Using data from the Canadian Multicentre Osteoporosis Study, several risk factors predictive of imminent (2-year) risk of low-trauma non-vertebral fracture among high-risk women were identified, inclu...

Bone Health > Fracture Risk > Prediction ModelsPerimenopause/Menopause > Osteoporosis > Fracture EpidemiologyResearch Methodology > Prospective Cohort Studies > Population-Based

A Randomized Trial of Progesterone in Women with Bleeding in Early Pregnancy

Coomarasamy A et al., 2019 New England Journal of Medicine

Background: Bleeding in early pregnancy is strongly associated with pregnancy loss. Progesterone is essential for the maintenance of pregnancy. Several small trials have suggested that progesterone th...

Pregnancy > Threatened Miscarriage > Progesterone TherapyPregnancy > Early Pregnancy Loss > Randomized Controlled TrialReproductive Endocrinology > Progesterone > Clinical Trials

Longitudinal assessment of health-related quality of life in osteoporosis: data from the population-based Canadian Multicentre Osteoporosis Study

W M Hopman et al., 2019 Osteoporos Int

Little is known about the association between health-related quality of life (HRQOL) and osteoporosis in the absence of fracture, and how HRQOL may change over time. This study provides evidence of su...

Bone Health > Osteoporosis > Quality of LifePerimenopause/Menopause > Osteoporosis > Patient-Reported OutcomesResearch Methodology > Prospective Cohort Studies > Longitudinal Assessment

Sperm DNA fragmentation and recurrent pregnancy loss: a systematic review and meta-analysis

McQueen DB et al., 2019 Fertility and Sterility

Objective: To investigate the rate of sperm DNA fragmentation in male partners of women with recurrent pregnancy loss and fertile control women. Design: Systematic review and meta-analysis. Setting: N...

Andrology > Sperm Quality > DNA FragmentationInfertility > Recurrent Pregnancy Loss > Male FactorResearch Methodology > Systematic Reviews > Meta-Analysis

Parity and lactation are not associated with incident fragility fractures or radiographic vertebral fractures over 16 years of follow-up: Canadian Multicentre Osteoporosis Study (CaMos)

Cooke-Hubley S et al., 2019 Archives of Osteoporosis

Parity and lactation showed no associations with incident clinical fragility fractures or radiographic vertebral compression fractures in the 16-year CaMos prospective study. Parity was associated wit...

Bone Health > Fracture Risk > Reproductive HistoryPostpartum > Lactation > Bone Health OutcomesReproductive Endocrinology > Pregnancy and Lactation > Bone Metabolism

Can Menopause Prediction Be Improved With Multiple AMH Measurements? Results From the Prospective Doetinchem Cohort Study

de Kat AC et al., 2019 The Journal of Clinical Endocrinology and Metabolism

Context: Anti-Müllerian hormone (AMH) levels are used worldwide as a screening tool for the duration of the female reproductive lifespan. Although AMH levels are associated with age at menopause, indi...

Perimenopause/Menopause > Menopause Prediction > AMH BiomarkerDiagnostics > Ovarian Reserve Testing > Anti-Müllerian HormoneResearch Methodology > Longitudinal Studies > Biomarker Modeling

SUN-537 Progesterone Therapy and Serum Sclerostin Levels in Healthy Menopausal Women: A 3-month Randomized, Placebo Controlled Clinical Trial

Yang Y et al., 2019 Open Access Journal of the Endocrine Society

Sclerostin is an osteocyte-produced glycoprotein that inhibits the WNT/β-catenin pathway essential for bone formation. Sclerostin was postulated to relate to normal bone metabolism in 2001; we still h...

Bone Health > Bone Formation Markers > SclerostinPerimenopause/Menopause > Hormone Therapy > ProgesteroneReproductive Endocrinology > Progesterone > Bone Metabolism

MON-LB042 Health-Related Quality of Life in Women with Polycystic Ovary Syndrome/Anovulatory Androgen Excess versus Local Population-Based Control Women (from the British Columbia Canadian Multicentre Osteoporosis Study [BC CaMos])

Liang B et al., 2019 Open Access Journal of the Endocrine Society

Polycystic Ovary Syndrome (PCOS) affects 5-20% of reproductive-aged women and is associated with lower Health-Related Quality of Life (HRQoL)1,2,3. HRQoL in PCOS, however, is often determined in small...

PCOS > Quality of Life > SF-36 AssessmentPCOS > Mental Health > Emotional Well-BeingResearch Methodology > Cross-Sectional Studies > Population-Based Comparisons

Systemic administration of low-dose naltrexone increases bone mass due to blockade of opioid growth factor receptor signaling in mice osteoblasts

Tanaka K et al., 2019 Life Sciences

AIMS: Opioid receptor blockers such as naloxone and naltrexone have been suggested to have a bone mass-increasing effect. However, the mechanisms at play have not been clarified. We examined the effec...

Bone Health > Bone Formation > Opioid Receptor ModulationReproductive Endocrinology > Pharmacology > Low-Dose NaltrexoneResearch Methodology > Animal Studies > Bone Metabolism

The role of the midwife in the therapy of infertility in Poland in the opinion of patients

Neneman M et al., 2019 Open Access Nursing and Public Health

Background. Infertility is a disease of the reproductive system manifesting with the inability to get pregnant within a minimum of 12 months. In diagnosing infertility and the therapeutic process, pha...

NaProTECHNOLOGY > Clinical Practice > Midwifery RoleInfertility > Patient Perspectives > Opinions on CareNaProTECHNOLOGY > Diagnosis and Treatment > Reproductive Health Disorders

Perfect- and typical-use effectiveness of the Dot fertility app over 13 cycles: results from a prospective contraceptive effectiveness trial

Jennings V et al., 2019 The European Journal of Contraception & Reproductive Health Care : the Official Journal of the European Society of Contraception

Objective: Dynamic Optimal Timing (Dot) is a smartphone application (app) that estimates the menstrual cycle fertile window based on the user's menstrual period start dates. Dot uses machine learning ...

Fertility Awareness > Digital Tools > Smartphone ApplicationsContraception/Comparison > Effectiveness Studies > Typical and Perfect UseFertility Awareness > Methods > Fertile Window Estimation

The role of lymphocytes in fetal development and recurrent pregnancy loss

Modzelewski J et al., 2019 Open Access Ginekologia Polska

Fetal survival and development is supported by the maternal immune system. Questions regarding those mechanisms have risen from development of transplantation medicine and observation of graft rejecti...

Pregnancy > Recurrent Pregnancy Loss > Immunological CausesReproductive Endocrinology > Immunology > Lymphocyte Function in PregnancyPregnancy > Recurrent Pregnancy Loss > Therapeutic Approaches

Uterine scar rupture - Prediction, prevention, diagnosis, and management

Tanos V et al., 2019 Best Practice & Research. Clinical Obstetrics & Gynaecology

The increasing rate of elective and indicated caesarean sections worldwide has led to new pathologies and management challenges. The number of patients undergoing trial of labor after caesarean sectio...

Surgery > Uterine Surgery > Cesarean Scar ManagementGeneral OB/GYN > Labor and Delivery > Trial of Labor After CesareanSurgery > Minimally Invasive > Isthmocele Repair

The Radiology of Osteoporotic Vertebral Fractures Revisited

Brian Lentle et al., 2019 J Bone Miner Res

Until recently there has been little evidence available to validate any method by which to make an accurate diagnosis of an osteoporotic vertebral fractures (OVFs) from plain radiographs. In part this...

Bone Health > Diagnostics > Vertebral Fracture AssessmentBone Health > Osteoporosis > Radiographic DiagnosisDiagnostics > Imaging > Vertebral Morphometry vs Morphology

Naltrexone: A History and Future Directions

Srivastava AB et al., 2019 Cerebrum : the Dana Forum on Brain Science

Trying to kick drug addiction without medicines is said to be like relying on willpower to overcome diabetes or asthma. Enter naltrexone, which has been around since 1984 and reduces the cravings for ...

Reproductive EndocrinologyGeneral OB/GYN

Incident Fragility Fractures Have a Long-Term Negative Impact on Health-Related Quality of Life of Older People: The Canadian Multicentre Osteoporosis Study

Sayem Borhan et al., 2019 J Bone Miner Res

Although the short-term impact of incident fragility fractures on health-related quality of life (HRQL) of older people has been confirmed, we lack long-term evidence. We explored the impact of incide...

Bone Health > Fractures > Quality of Life ImpactBone Health > Osteoporosis > Prospective Cohort StudiesPerimenopause/Menopause > Bone Health > Fracture Outcomes

A Quantitative Self-Assessment of Seminarians' Response to a Curriculum Addition on Marriage, Sexuality, FertilityCare, and Naprotechnology: The Kenrick-Glennon Experience (2006-2015)

Daly KD et al., 2019 The Linacre Quarterly

A special course on Marriage, the Family and Human Sexuality was established at Kenrick-Glennon Seminary in St. Louis so as to assist the seminarians in their better understanding of the Church's teac...

NaProTECHNOLOGY > Education > Seminary and Clergy FormationFertility Awareness > Education > NFP Curriculum OutcomesEthics/Philosophy > Catholic Teaching > Humanae Vitae Implementation

Frailty and Risk of Fractures in Patients With Type 2 Diabetes

Guowei Li et al., 2019 Diabetes Care

Objective: We aimed to explore whether frailty was associated with fracture risk and whether frailty could modify the propensity of type 2 diabetes toward increased risk of fractures.Research design a...

Bone Health > Fractures > Risk Factors in DiabetesBone Health > Osteoporosis > Frailty and Fracture RiskResearch Methodology > Prospective Cohort > Fracture Prediction

ACOG Practice Bulletin No. 206: Use of Hormonal Contraception in Women With Coexisting Medical Conditions

ACOG, 2019 Obstetrics and Gynecology

Although numerous studies have addressed the safety and effectiveness of hormonal contraceptive use in healthy women, data regarding women with underlying medical conditions or other special circumsta...

Contraception/Comparison > Guidelines > Medical Eligibility CriteriaContraception/Comparison > Safety > Coexisting Medical ConditionsGeneral OB/GYN > Clinical Guidelines > ACOG Practice Bulletins