Westerman R et al.2021
Open Access
Reproductive Biomedicine & Society Online
Metabolic risk factors such as obesity are considered major obstacles to female fertility. Chronic infertility imposes psychological and social burdens on women because infertility violates societal g...
Bergh E et al.2021Obstetrics and Gynecology Clinics of North America
The field of fetal medicine has evolved significantly over the past several decades. Our ability to identify and treat the unborn patient has been shaped by advancements in imaging technology, genetic...
ObjectiveS: tudies on the effect of long-term use of combined oral contraceptives (COCs) on cervical dysplasia and/or cancer risk have been inconsistent. Less is known about the effects of other forms...
# State of the fertility sector 2020/21
**Annual publication on HFEA licensed clinics**
Published: November 2021
[**Download the underlying dataset as .xlsx**](https://www.hfea.gov.uk/media/5czb4k2o/2...
UK Fertility RegulationIndustry StatisticsFertility Sector Oversight
OBJECTIVES: Mice are widely used as an animal model for studying human uterine receptivity for embryo implantation. Although transcriptional changes related to mouse uterine receptivity have been dete...
The physiology of testosterone as a normal female hormone in reproductive years and beyond is poorly taught and understood. This has led to unregulated and dangerous prescribing practices by physician...
Bouchard TP et al.2021Expert Review of Molecular Diagnostics
Background: A new fertility monitor is now available that provides quantitative measurement of urinary hormones, but clinical use requires validation against an established fertility monitor that prov...
Infrared light (760 nm-1 mm) constitutes approximately 40% of the solar radiation reaching the ground at sea level. Shortest wavelength near-infrared (NIR) photons (NIR or IR-A: 760-1,400 nm) can pene...
Thiamine or vitamin B1 is an essential, water-soluble vitamin required for mitochondrial energetics-the production of adenosine triphosphate (ATP). It is a critical and rate-limiting cofactor to multi...
Shirin S et al.2021
Open Access
Medicina (Kaunas, Lithuania)
Background and Objectives: Women with androgenic Polycystic Ovary Syndrome (PCOS) have increased endometrial cancer risk that cyclic progesterone will prevent; it may also reverse PCOS's neuroendocrin...
Pacu I et al.2021
Open Access
Experimental and Therapeutic Medicine
Couple infertility is a pathology with an absolute number of cases growing markedly over the last decade in connection mainly with the increased age of couples wishing to conceive. Platelet-rich plasm...
Kuroda K et al.2021
Open Access
Reproductive Medicine and Biology
Purpose: Does the OPtimization of Thyroid function, Thrombophilia, Immunity, and Uterine Milieu (OPTIMUM) treatment strategy, developed for treating repeated implantation failure (RIF), contribute to ...
OBJECTIVES: Functional hypothalamic amenorrhoea (FHA) is a common cause of amenorrhoea, but diagnosis can be challenging. The aim of this study was to investigate the clinical and biochemical features...
To investigate the sociological, environmental, and economic impact of hormonally active contraceptives, a series of comprehensive literature surveys were employed. Sociological effects are discussed ...
Petca A et al.2021
Open Access
Experimental and Therapeutic Medicine
α-Lipoic acid (ALA) is a natural molecule that is inconsistently synthesized by the human body and must be provided from exogenous sources, such as food and dietary supplements. Once absorbed, the oxi...
Favaro C et al.2021
Open Access
Journal of Women's Health (2002)
Background: Time to pregnancy (TTP) is a biomarker of fecundability and has been associated with behavioral and environmental characteristics; however, these associations have not been examined in a l...
Cumulus cells (CCs) originating from undifferentiated granulosa cells (GCs) differentiate in mural granulosa cells (MGCs) and CCs during antrum formation in the follicle by the distribution of locatio...
The 2019 Assisted Reproductive Technology (ART) Fertility Clinic and National Summary Report, prepared by the Centers for Disease Control and Prevention (CDC) under the Fertility Clinic Success Rate a...
Estradiol, an estrogen steroid hormone, serves as the dominant female hormone and its levels fluctuate during lifetime. In women, after the menopause, all estrogens and almost all androgens are locall...
Nijsten K et al.2021Acta obstetricia et gynecologica Scandinavica
INTRODUCTION: Hyperemesis gravidarum (HG) complicates 1% of pregnancies and has a major impact on maternal quality of life and well-being. We know very little about HG's long-term impact after an affe...
Chang WH et al.2021Science of The Total Environment
Phthalate esters (PAEs) are one of the most widely used plasticizers in polymer products and humans are increasingly exposed to them. The constant exposure to PAEs-contained products has raised some c...
Marcu I et al.2021
Open Access
Translational Andrology and Urology
Background: Glomerulations are not specific for interstitial cystitis/bladder pain syndrome (IC/BPS). Controversy exists about whether cystoscopic findings differ between patients with and without low...
In recent years, the term 'medical gaslighting' and accompanying accounts of self-identified women experiencing invalidation, dismissal and inadequate care have proliferated in the media. Gaslighting ...
Gender Bias in MedicineMedical GaslightingStructural Healthcare Barriers
Morssinkhof MWL et al.2021
Open Access
Psychoneuroendocrinology
Background: Worldwide, oral contraceptive (OC) use is a very common form of birth control, although it has been associated with symptoms of depression and insomnia. Insomnia is a risk factor for major...
Depression and MoodSleep and InsomniaLongitudinal Cohort Study
Martínez Leo EE et al.2021Nutrition (Burbank, Los Angeles County, Calif.)
In recent years, consumption of ultra-processed food around the world has been increasing. The nutritional profile of an ultra-processed diet is associated with the development of cellular alterations...
Ultra-Processed Diet EffectsOxidative Stress and Immune Tolerance
People living with HIV are ageing, and a growing number of women living with HIV are entering menopause. Women living with HIV commonly have bothersome vasomotor symptoms and onset of menopause at ear...
Hormone Therapy in HIVHIV-Associated Bone LossVasomotor Symptoms Management
Introduction: Women living with HIV (WLWH) experience accelerated ageing and an increased risk of age-associated diseases earlier in life, compared with women without HIV. This is likely due to a comb...
Peebles K et al.2021Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
BACKGROUND: Limited evidence suggests that the nonhormonal contraceptive copper intrauterine device (Cu-IUD) may increase bacterial vaginosis (BV) risk, possibly due to increased volume and duration o...
OBJECTIVE: To study childbirth and the risk of miscarriage and infertility among women who have received a diagnosis of type 2 diabetes before the start of their reproductive journey.
DESIGN: Registe...
Alonso Pacheco L et al.2021Archives of Gynecology and Obstetrics
PURPOSE: To investigate and propose a new simple tridimensional (3D) ultrasonographic method to diagnose a T-shaped uterus (Class U1a).
METHODS: A multicenter non-experimental case-control diagnostic...
3D Ultrasound Uterine AnomaliesT-Shaped Uterus DiagnosisCase-Control Diagnostic Accuracy
Bliuc D et al.2021Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research
Cognitive decline and osteoporosis often coexist and some evidence suggests a causal link. However, there are no data on the longitudinal relationship between cognitive decline, bone loss and fracture...
Cognitive Decline and Bone LossProspective Cohort StudiesLongitudinal Population-Based Study
OBJECTIVE: This study investigated the effects of Tartrazine and Erythrosine (T+E) on the reproductive hormones and expression of some pro-inflammatory cytokines and testicular genes in testis of male...
Anderl C et al.2021
Open Access
Journal of Child Psychology and Psychiatry, and Allied Disciplines
Background: Because of the widespread use of oral contraceptives (OCs) and the devastating effects of depression both on an individual and a societal level, it is crucial to understand the nature of t...
Stanford JB et al.2021
Open Access
BMC Pregnancy and Childbirth
Background: Restorative reproductive medicine (RRM) seeks to identify and correct underlying causes and factors contributing to infertility and reproductive dysfunction. Many components of RRM are hig...
Hormonal contraception exposes women to synthetic progesterone receptor (PR) agonists, progestins, and transiently increases breast cancer risk. How progesterone and progestins affect the breast epith...
Turner JV2021The journal of obstetrics and gynaecology research
AIM: Simplified contraceptive method-efficacy and/or typical-use effectiveness rates are commonly used for direct comparison of the various contraceptive methods. Use of such effectiveness rates in th...
OBJECTIVE: Evaluation of vitamin D supplementation on ovarian reserve in women with diminished ovarian reserve and vitamin D deficiency.
METHODS: The study is a before-and-after intervention study th...
Alvarez-Mon MA et al.2021
Open Access
Frontiers in Public Health
Background: Media outlets influence social attitudes toward health habits. The analysis of tweets has become a tool for health researchers.
Objective: The objective of this study was to investigate t...
Buskmiller C et al.2021Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology
Objective: Preoperative short cervical length (CL) remains a major risk factor for preterm birth after laser surgery for twin-twin transfusion syndrome (TTTS), but the optimal intervention to prolong ...
Shieh A et al.2021The Journal of clinical endocrinology and metabolism
CONTEXT: Bone mineral density (BMD) decreases rapidly during menopause transition (MT), and continues to decline in postmenopause.
OBJECTIVE: This work aims to examine whether faster BMD loss during ...
Tenório MCDS et al.2021Antioxidants (Basel, Switzerland)
N-acetylcysteine (NAC) is a medicine widely used to treat paracetamol overdose and as a mucolytic compound. It has a well-established safety profile, and its toxicity is uncommon and dependent on the ...
Zhu TY et al.2021Journal of medical Internet research
BACKGROUND: As a daily point measurement, basal body temperature (BBT) might not be able to capture the temperature shift in the menstrual cycle because a single temperature measurement is present on ...
Ramasamy R et al.2021Environmental Science and Pollution Research
Microfiber pollution is one of the recent threats to sustainability. Due to the increased use of synthetic textiles, microplastic fiber release to the environment has increased exponentially. This rev...
This paper looks at the ethics of assisted reproductive technology (ART) from the perspective of the Catholic Church. The three criteria of evaluation of the ethics of ART are the right to life and ph...
Catholic BioethicsEthical Alternative to ARTNaProTECHNOLOGY
# Fertility treatment 2019: trends and figures
UK statistics for IVF and DI treatment, storage, and donation
Published: May 2021
Fertility trends is our annual statistical release. The key findings ar...
IVF Success RatesPopulation StatisticsNational Registry Data
CONTEXT: Phthalate exposure is associated with altered reproductive function, but little is known about associations of phthalate exposure with risk of hot flashes.
OBJECTIVE: To investigate associat...