STUDY QUESTION: What were the utilization, effectiveness and safety of practices in assisted reproductive technologies (ART) globally in 2014 and what global trends could be observed?
SUMMARY ANSWER:...
Annual report (Jahrbuch) of the Deutsches IVF-Register (DIR) for treatment year 2020. DIR is the German national IVF/ICSI registry, founded 1982 — the oldest continuously operating ART registry. Volun...
Annual summary report on assisted reproductive technology (ART) cycles performed in Japan during 2018, published by the Ethics Committee of the Japan Society of Obstetrics and Gynecology (JSOG).
Agence de la biomédecine2021Agence de la biomédecine
Rapport annuel d'AMP Vigilance 2020 publié par l'Agence de la biomédecine. Document de surveillance pour les activités d'Assistance Médicale à la Procréation en France couvrant les incidents et effets...
Background: In elite athletes, training individualization is widely recommended to optimize competitive performance. Previous studies have evidenced the impact of hormonal fluctuations on different pe...
Sims ST et al.2021BMJ open sport & exercise medicine
INTRODUCTION: As the number of female athletes competing rises globally, training methodologies should reflect sex differences across critical metrics of adaptation to training. Surrogate markers of t...
Li Y et al.2021Journal of clinical laboratory analysis
BACKGROUND: Spontaneous abortion occurs in 15% ~ 25% of clinical pregnancy. β-human chorionic gonadotropin (β-HCG) and progesterone (P) have been widely used in early pregnancy assessment, but their c...
The purpose of the study was TO analyze the fetoplacental complex hormone levels and changes in their dynamics in pregnant women with miscarriage and the impact of these features on the subsequent cou...
BACKGROUND: Most evidence for interpregnancy interval (IPI) and adverse birth outcomes come from studies that are prone to incomplete control for confounders that vary between women. Comparing pregnan...
Jiang Y et al.2021Oxidative medicine and cellular longevity
Oxidative stress has been recognized as one of the causal mediators of female infertility by affecting the oocyte quality and early embryo development. Improving oxidative stress is essential for repr...
Dorani F et al.2021Journal of psychiatric research
This is the first study to assess the prevalence of symptoms of premenstrual dysphoric disorder (PMDD), episodes of postpartum depression symptoms (PPD) after first childbirth, and climacteric mood sy...
Guo Y et al.2021Evidence-based complementary and alternative medicine : eCAM
Endometriosis (EM) is a common and benign estrogen-dependent gynecological disorder among women of reproductive age, and secondary dysmenorrhea is one of the more severe symptoms. However, the mechani...
The neuropeptide oxytocin acts as a hormone and a neuromodulator, influencing a multitude of human social behaviors, including reproduction. During childbirth and the postpartum period, it plays a key...
Areta JL et al.2021European journal of applied physiology
Energy availability (EA) is defined as the amount of dietary energy available to sustain physiological function after subtracting the energetic cost of exercise. Insufficient EA due to increased exerc...
Ludovichetti FS et al.2021Reproduction & fertility
Today periodontal health is considered as an integral part of systemic health itself and no longer as a single factor. The literature recognizes that the presence of periodontal disease can represent ...
Nanotechnology has enabled tremendous breakthroughs in the development of materials and, nowadays, is well established in various economic fields. Among the various nanomaterials, TiO2 nanoparticles (...
Pearson JT et al.2020Journal of Women's Health (2002)
Background: Digital fertility awareness-based methods of birth control are an attractive alternative to hormonal or invasive birth control for modern women. They are also popular among women who may b...
App-Based MethodsFertility Awareness MethodsProspective Cohort Study
Stafford IA et al.2020American Journal of Obstetrics & Gynecology MFM
Background: Incidence, risk factors, and perinatal morbidity and mortality rates related to amniotic fluid embolism remain a challenge to evaluate, given the presence of differing international diagno...
Buskmiller C et al.2020Fetal Diagnosis and Therapy
Objective: Function of the lower extremities after prenatal myelomeningocele (MMC) repair is best assessed with ambulatory function at 30-36 months of age, but parents often ask about function before ...
Shen H et al.2020
Open Access
The Journal of International Medical Research
Objective: To examine potential risk factors associated with the success rate following fallopian tube recanalization (FTR) in infertile women with obstruction of the proximal fallopian tube.
Methods...
Reproductive health is compromised during anorexia nervosa (AN). However, it is still unclear whether this medical complication is reversible after recovery from AN. The purpose of this paper was to c...
Larsen SV et al.2020
Open Access
Acta Psychiatrica Scandinavica
Objective: Sex steroid hormones potently shape brain functions, including those critical to maintain mental health such as serotonin signaling. Use of oral contraceptives (OCs) profoundly changes endo...
Despite the available research investigating uterine physiology during and immediately following pregnancy, including at the vascular and muscular levels, knowledge of the potential long-term timeline...
The 2018 Assisted Reproductive Technology (ART) Fertility Clinic Success Rates Report, prepared under the Fertility Clinic Success Rate and Certification Act of 1992 (Public Law 102-493), presents dat...
Bariani MV et al.2020Current opinion in endocrinology, diabetes, and obesity
PURPOSE OF REVIEW: Uterine leiomyoma (fibroids) is a gynecologic disorder impacting the majority of women in the United States. When symptomatic, these noncancerous tumors can cause severe morbidity i...
Rondanelli M et al.2020Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)
BACKGROUND: Boron is a trace element that plays an important role in numerous biological functions, including calcium metabolism, growth and maintenance of bone tissue. However, there are still no pre...
Samartzis EP et al.2020Annals of translational medicine
Endometriosis is a benign gynecologic condition affecting up to one woman out of ten of reproductive age. It is defined by the presence of endometrial-like tissue in localizations outside of the uteri...
Vitale SG et al.2020International Journal of Food Sciences and Nutrition
This study aims to evaluate the effects of myo-inositol supplementation on gestational diabetes mellitus (GDM) rates and body water distribution in overweight non-obese women. 223 overweight non-obese...
Konicki AJ et al.2020Journal of Christian Nursing : a Quarterly Publication of Nurses Christian Fellowship
Infertility affects one in 16 married women in the United States where 12.7% of these seek treatment. The stress of infertility and treatment is known to impact marital satisfaction, which can be furt...
Stanford JB et al.2020Reproductive Biomedicine Online
While we agree with many of the points stated by Dyer et al. in their recent commentary inRBMO(Dyer et al., 2020), we believe their conclusions are focused too narrowly. Limiting the indicator of acce...
Kiani AK et al.2020Acta Bio-medica : Atenei Parmensis
BACKGROUND AND AIM: Infertility affects ~20% of the couples in the world. Assisted reproductive technologies (ARTs) are currently the most common treatment option for infertility. Nevertheless, ARTs m...
# State of the fertility sector 2019/2020
**Annual publication on our regulatory work**
Published: November 2020
[**Download the underlying data set as.xlsx (47KB)**](https://www.hfea.gov.uk/media/328...
OBJECTIVE: To investigate the current evidence that correlates impaired male fertility with the risk of developing male-related malignancies.
DESIGN: Systematic review and meta-analysis of population...
Horodenchuk Z et al.2020Kwartalnik Naukowy Fides et Ratio
Objective: To assess the outcomes of treatment the couples with infertility or recurrent miscarriage with restorative reproductive approach and to identify predictors of success.
Methods: It was a re...
We herein summarise the evidence concerning the impact of sperm DNA fragmentation in various clinical infertility scenarios and the advances on sperm DNA fragmentation tests. The collected evidence wa...
Mosorin ME et al.2020European Journal of Endocrinology
Objective: The use of combined hormonal contraceptives (CHCs) worsens glucose tolerance, but the risk for glucose metabolism disorders remains controversial.
Design: The study is a prospective longitu...
Background: Hormonal contraceptive drugs are being used by adult and adolescent women all over the world. Convergent evidence from animal research indicates that contraceptive substances can alter bot...
Background: Oral contraceptive use has been previously associated with an increased risk of suicidal behavior in some, but not all, samples. The use of large, representative, longitudinally-assessed s...
Kaneshiro B et al.2020Hawai'i Journal of Health & Social Welfare
Long acting reversible contraceptives (LARC), including intrauterine devices (IUDs) and contraceptive implants, can support an individual in meeting their reproductive goals by allowing them to preven...
Rabijewski M et al.2020
Open Access
Ginekologia Polska
Dehydroepiandrosterone (DHEA) concentration decreases with age, therefore, DHEA has been considered a hormone that reduces the symptoms associated with aging, so the usefulness of DHEA in premenopausa...
Dahlke JD et al.2020
Open Access
Obstetrics and Gynecology
In this Commentary, we explain the case for a standardized cesarean delivery surgical technique. There are three strong arguments for a standardized approach to cesarean delivery, the most common majo...
OBJECTIVE: To consolidate evidence from systematic reviews and meta-analyses investigating the association between reproductive factors in women of reproductive age and their subsequent risk of cardio...
Skorseth P et al.2020Orthopaedic journal of sports medicine
BACKGROUND: Investigations of the female athlete triad (Triad) in high school athletes have found that 36% had low energy availability, 54% had menstrual abnormalities, and 16% had low bone mineral de...
Cetin E et al.2020Current opinion in obstetrics & gynecology
PURPOSE OF REVIEW: Uterine fibroids are the most common benign neoplasms of the female reproductive tract and one of the major public health concerns. Although most women with uterine fibroids are asy...
McNulty KL et al.2020Sports medicine (Auckland, N.Z.)
BACKGROUND: Concentrations of endogenous sex hormones fluctuate across the menstrual cycle (MC), which could have implications for exercise performance in women. At present, data are conflicting, with...
Per- and polyfluoroalkyl substances (PFASs) are used in specialty/functional textiles to impart oil, water, and stain repellency. Little is known, however, with regard to the occurrence of PFASs in te...
AbstractObjectiveTo evaluate whether irregular or long menstrual cycles throughout the life course are associated with all cause and cause specific premature mortality (age <70 years).
Design: Prospe...
DeVilbiss EA et al.2020Paediatric and Perinatal Epidemiology
Background: Attaining pregnancy is conditional upon a series of complex processes, including adequately timed intercourse, ovulation, fertilisation, and implantation. Anovulation is a first-line treat...