Lifestyle and Environment · Environmental Exposures

Obesogens and Obesity: State-of-the-Science and Future Directions Summary from a Healthy Environment and Endocrine Disruptors Strategies Workshop

Heindel JJ, Alvarez JA, Atlas E, Cave MC, Chatzi VL, Collier D, Corkey B, Fischer D, Goran MI, Howard S, Kahan S, Kayhoe M, Koliwad S, Kotz CM, La Merrill M, Lobstein T, Lumeng C, Ludwig DS, Lustig RH, Myers P, Nadal A, Trasande L, Redman LM, Rodeheffer MS, Sargis RM, Stephens JM, Ziegler TR, Blumberg B

Published July 2023 The American journal of clinical nutrition
DOI 10.1016/j.ajcnut.2023.05.024 PMID 37230178 PMC PMC10731763

Abstract

On September 7 and 8, 2022, Healthy Environment and Endocrine Disruptors Strategies, an Environmental Health Sciences program, convened a scientific workshop of relevant stakeholders involved in obesity, toxicology, or obesogen research to review the state of the science regarding the role of obesogenic chemicals that might be contributing to the obesity pandemic. The workshop's objectives were to examine the evidence supporting the hypothesis that obesogens contribute to the etiology of human obesity; to discuss opportunities for improved understanding, acceptance, and dissemination of obesogens as contributors to the obesity pandemic; and to consider the need for future research and potential mitigation strategies. This report details the discussions, key areas of agreement, and future opportunities to prevent obesity. The attendees agreed that environmental obesogens are real, significant, and a contributor at some degree to weight gain at the individual level and to the global obesity and metabolic disease pandemic at a societal level; moreover, it is at least, in theory, remediable.

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Lifestyle and Environment › Environmental Exposures › Endocrine Disrupting Chemicals
Jerrold J Heindel, Jessica A Alvarez, Ella Atlas, Matthew C Cave, Vaia Lida Chatzi, David Collier, Barbara Corkey, Douglas Fischer, Michael I Goran, Sarah Howard, Scott Kahan, Matthias Kayhoe, Suneil Koliwad, Catherine M Kotz, Michele La Merrill, Tim Lobstein, Carey Lumeng, David S Ludwig, Robert H Lustig, Pete Myers, Leonardo Trasande, Matthew S Rodeheffer, Robert M Sargis, Jacqueline M Stephens, Thomas R Ziegler, Bruce Blumberg
J Heindel, Jess Alvarez, J Alvarez, E Atlas, Matt Cave, M Cave, V Chatzi, Dave Collier, D Collier, Barb Corkey, B Corkey, Doug Fischer, D Fischer, Mike Goran, M Goran, S Howard, S Kahan, M Kayhoe, S Koliwad, Cathy Kotz, Kate Kotz, C Kotz, M Merrill, Timothy Lobstein, T Lobstein, C Lumeng, Dave Ludwig, D Ludwig, Bob Lustig, Rob Lustig, Bobby Lustig, R Lustig, Peter Myers, P Myers, L Trasande, Matt Rodeheffer, M Rodeheffer, Bob Sargis, Rob Sargis, Bobby Sargis, R Sargis, J Stephens, Tom Ziegler, T Ziegler, B Blumberg
PMID 37230178 37230178 DOI 10.1016/j.ajcnut.2023.05.024 10.1016/j.ajcnut.2023.05.024 Heindel et al. 2023, Heindel 2023