Don't ignore perimenopause

Jerilynn C Prior; Christine L Hitchcock; Sonia Shirin; Georgina Hale; Azita Goshtasebi

doi:10.1503/cmaj.148952-l

Perimenopause and Menopause Hormone Therapy

Don't ignore perimenopause

Prior JC, Hitchcock CL, Shirin S, Hale G, Goshtasebi A

Published July 31, 2023 CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 195(29), E987

DOI 10.1503/cmaj.148952-l PMID 37524397 PMC PMC10395791

Abstract

We agree with Lega and colleagues that menopausal hormone therapy (MHT) has been shown in randomized controlled trials (RCTs) to be effective and safe for treating problematic vasomotor symptoms related to menopause. We also agree that treating menopausal vasomotor symptoms is important to decrease later life risks for heart disease and osteoporotic fracture. For women or people born with ovaries who do not wish to, or cannot, take estrogen-based therapy for vasomotor symptoms, oral micronized progesterone has been shown to be both effective and safe in menopause in an RCT, but this practical information was not provided in Lega and colleagues’ review.

Topics

Perimenopause and Menopause › Hormone Therapy › Benefits and Risks · Therapeutics › Hormonal Agents › Estrogen Preparations

Jerilynn C Prior, Christine L Hitchcock, Sonia Shirin, Georgina Hale, Azita Goshtasebi

J Prior, Chris Hitchcock, C Hitchcock, S Shirin, G Hale, A Goshtasebi

PMID 37524397 37524397 DOI 10.1503/cmaj.148952-l 10.1503/cmaj.148952-l Prior et al. 2023, Prior 2023

Don't ignore perimenopause

Abstract

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