Predictors of time to live birth in the iNEST study

Infertility is a common problem, with multiple underlying causes. • Natural Procreative Technology (NPT) is a systematic approach to optimize normal reproductive function so pregnancy can occur in vivo. The international NaProTechnology Evaluation and Surveillance of Treatment (iNEST) study aims to determine 1) characteristics of couples seeking NPT treatment 2) live birth rates over time for patients who are treated with NPT or other treatments for infertility or history of miscarriage Longitudinal Cohort • Couples presenting with goal of child • Main outcome: cumulative live births • 2006-2016 Follow-up • Up to 3 years The cumulative proportion with live birth was related to woman’s age, parity, time trying, prior IVF or AI, and surgery Woman’s age, parity, time trying, and prior treatment all had impact on cumulative probability of live birth in the expected direction. • Woman’s surgery (mainly laparoscopy) had impact in an unexpected direction (lower probability of live birth with surgery).