Analysis of Laparoscopic and Transvaginal Ovarian Drilling on Polycystic Ovarian Syndrome: A Narrative Review of Outcomes

  • Philadelphia College of Osteopathic Medicine ROR
  • Johns Hopkins University ROR
  • Augusta University ROR
  • Allama Iqbal Medical College ROR
  • Bahçeşehir University ROR
  • Civil Hospital Karachi ROR
  • Zagazig University ROR
  • Omdurman Islamic University ROR
  • Cairo University ROR

Cureus, 18(2), e103930

DOI 10.7759/cureus.103930 PMID 41873282 Source

Abstract

The primary objective of polycystic ovarian syndrome (PCOS) treatment is to achieve mono-ovulatory cycles, thereby enabling pregnancy and childbirth. Laparoscopic ovarian drilling (LOD) and transvaginal ovarian drilling (TVOD) are widely used second-line treatments for ovulation induction in PCOS patients who do not respond to clomiphene citrate (CC). LOD involves the application of heat or laser energy to create small perforations in the ovary, whereas TVOD involves ultrasound-guided ovarian puncture. Both LOD and TVOD have been shown to be effective in promoting ovulation and enhancing fertility outcomes in PCOS patients. TVOD offers several potential advantages over LOD, including a lower risk of surgical complications, reduced cost, and the ability to be performed in an outpatient setting. Both LOD and TVOD are effective treatment options for PCOS-related infertility. The choice between the two procedures should be based on individual patient characteristics, including body mass index (BMI), hormonal profiles, and previous responses to treatment. Further research is needed to optimize these techniques and clarify their clinical applications. Patients with clomiphene-resistant PCOS should be carefully assessed for both LOD and TVOD. LOD may be more suitable for patients with elevated luteinizing hormone (LH) levels and shorter durations of infertility. In contrast, TVOD may be preferred for patients who would benefit from a less invasive approach with a lower risk of adhesion formation.

Topics

laparoscopic ovarian drilling PCOS, transvaginal ovarian drilling outcomes, LOD TVOD comparison, ovarian drilling ovulation induction, PCOS second-line surgical treatment, ovarian drilling mono-ovulatory cycles, clomiphene-resistant PCOS drilling, minimally invasive ovarian surgery PCOS, ovarian drilling pregnancy outcomes, PCOS anovulation surgical management
PMID 41873282 41873282 DOI 10.7759/cureus.103930 10.7759/cureus.103930

Cite this article

Rivo, E., & Rock, J. (1965). The clinical use of clomiphene citrate. *Pacific Medicine and Surgery*, *73*(6), 413-420.

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