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Pacific Medicine and Surgery, 18(2), e103930, 2026

The clinical use of clomiphene citrate

Rukh Afzal M , Mah Rukh Afzal , Mohamed Alassar

Author affiliations (9)
  • Allama Iqbal Medical College ROR
  • Bahçeşehir University ROR
  • Civil Hospital Karachi ROR
  • Philadelphia College of Osteopathic Medicine ROR
  • Zagazig University ROR
  • Omdurman Islamic University ROR
  • Cairo University ROR
  • Augusta University ROR
  • Johns Hopkins University ROR
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Abstract not indexed. Read at source

Topics

PCOSSurgeryInfertility
laparoscopic ovarian drilling PCOS, transvaginal ovarian drilling outcomes, LOD TVOD comparison, ovarian drilling ovulation induction, PCOS second-line surgical treatment, ovarian drilling mono-ovulatory cycles, clomiphene-resistant PCOS drilling, minimally invasive ovarian surgery PCOS, ovarian drilling pregnancy outcomes, PCOS anovulation surgical management

Cite this article

Rivo, E., & Rock, J. (1965). The clinical use of clomiphene citrate. Pacific Medicine and Surgery, 73(6), 413-420.

Keywords

Adult, Clomiphene/therapeutic Use, Female, Humans, Menstruation Disturbances/drug Therapy, Ovulation/drug Effects, Pregnancy, Stilbenes/therapeutic Use, Stilbenes, Clomiphene

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Infertility is a world-wide problem, defined as failure to achieve pregnancy after 12 months of regular unprotected sexual intercourse. There are multiple causes for infertility involving both male and female factors. Fallopian tube occlusion is a common reason for female infertility. The initial attempts to treat proximal obstruction involved the use of a whalebone bougie positioned in the uterine cornua to dilate the proximal tube by Smith as early as 1849. Fluoroscopic fallopian tube recanalization for the treatment of infertility was first described in 1985. Since that time, there have been over 100 papers describing various methods for recanalization of occluded fallopian tubes. Fallopian tube recanalization is a minimally invasive procedure which is performed on an outpatient basis. It should be a first line therapy for patients with proximal occlusion of fallopian tubes.

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