Hysteroscopic Septoplasty

Hysteroscopic Septoplasty is the operative hysteroscopic procedure used to incise or resect a uterine septum, converting a septate uterine cavity into a single normal cavity. It is the definitive surgical treatment for septate uterus.

The procedure is performed under general or spinal anesthesia using a hysteroscopic resectoscope or office hysteroscope with scissors or monopolar/bipolar energy. Postoperative estrogen supplementation is commonly given to support endometrial regeneration across the incision site, though this practice has not been validated by major guidelines.

Evidence from randomized trials, including the TRUST trial, has been inconclusive regarding reproductive benefit, and current recurrent pregnancy loss guidelines offer hysteroscopic septoplasty alongside expectant management as a clinical option rather than a proven intervention. In Restorative Reproductive Medicine, hysteroscopic septoplasty is a standard corrective procedure for recurrent pregnancy loss patients with a confirmed uterine septum identified on workup.

This content is for educational purposes only and does not constitute medical advice. Consult an RRM clinician or healthcare provider for guidance specific to your situation.