American journal of reproductive immunology (New York, N.Y. : 1989), 84(3), e13255, 2020
Abstract
Chronic endometritis (CE) is an unusual inflammatory condition characterized by endometrial plasmacyte infiltration. It has a high prevalence in women with reproductive failure. Because of its characteristic localization patterns and molecular functions, syndecan-1 has been identified as a biomarker of plasmacyte, and syndecan-1 immunohistochemistry (IHC) becomes the most dependable diagnostic method for CE. In this review, we discuss the association between CE and reproductive failure, the clinicopathological characterization of CE, the function and expression of syndecan-1, the progress of syndecan-1 IHC in the diagnosis of CE, and the prediction of reproductive outcome.
Cite this article
Xu, Y., Mei, J., Diao, L., Li, Y., & Ding, L. (2020). Chronic endometritis and reproductive failure: Role of syndecan-1.. *American journal of reproductive immunology (New York, N.Y. : 1989)*, *84*(3), e13255. https://doi.org/10.1111/aji.13255
Xu Y, Mei J, Diao L, Li Y, Ding L. Chronic endometritis and reproductive failure: Role of syndecan-1.. American journal of reproductive immunology (New York, N.Y. : 1989). 2020;84(3):e13255. doi:10.1111/aji.13255
Keywords
chronic endometritis, plasmacyte, reproductive failure, syndecan-1